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The map label for this gene is flhA [H]

Identifier: 34496480

GI number: 34496480

Start: 1069240

End: 1071324

Strand: Reverse

Name: flhA [H]

Synonym: CV_1025

Alternate gene names: 34496480

Gene position: 1071324-1069240 (Counterclockwise)

Preceding gene: 34496481

Following gene: 34496479

Centisome position: 22.55

GC content: 64.89

Gene sequence:

>2085_bases
ATGGACTCCATCCTCCAGATATTGCGCACCATGAAGATCACCCAGCTCGCCGGGCCGCTGCTGATCATCCTCATTTTGAT
GATGATGATCCTGCCGCTGCCGCCGGTGCTGCTGGACATCTTCTTCACCTTCAACATCGCGGTGTCGGTGATCGTGCTGC
TGGTCGGCATCAATGTGCGCAAACCGCTGGACTTCTCGTCCTTTCCGTCGGTGCTGCTGATCACCACCATGCTGCGGCTG
TCGCTGAACGTCGCCTCCAGCCGGGTGGTGCTGCTGGAAGGCCATACCGGGCCGGACGCCGCCGGCAAGGTGATCGAATC
GTTCTCCCACTTTCTGGTGGGCGGCAACGTCGCCATCGGCATCGTGGTGTTCATCATCATCACCATCATCAACTTCGTGG
TGATCACCAAGGGCGCCGGCCGGATCGCCGAAGTGTCGGCGCGCTTCACCCTGGACGCGATGCCCGGCAAGCAGATGGCG
ATCGACGCCGACCTCAACGCCGGCCTGATCGGCGAGGACGAGGCCCGCAAGCGCCGCTCCACCATCGCCGAGGAAGCCAA
CTTCTTCGGCGCGATGGACGGTGCCTCCAAATACGTGCGCGGCGACGCGATGGCCGGCATCCTGATCATCCTGATCAACG
TGATAGGCGGCCTGATCGTCGGCGTGGTCCAGCACGACCTGCCAGTGGGACAGGCGGCGGAAACCTACACCCTGCTGAGC
ATAGGCGACGGCCTGGTCGCGCAGATCCCGGCGCTGATCATCTCCACCGCCGCCGGCATCGTGGTGACCCGCGTCGGCAC
CGACCAGGACATGTCGGAGCAGTTCCTGGGCCAGCTGTTCACCAAGCCGCAGGTGCTGTACATCACCTCGGCGGTGATCG
GCATGATAGGCCTGATCCCCAACATGCCGCATTTCGCCTTCCTGCTGATCGCCGGCTCGCTGCTGGCGCTGGCGCGCGGC
ATGGAGCGCCGCAACCGCCTGCGCCGGGAGAAGGAGCTGCAGGCCGCCGTCCAGCCCGCGGCGGCGCCCGAGCAGCAGGC
GGCCGAGGTCGGCTGGCACGACGTGCAGCACGTCGACCAGTTGGGGATGGAAGTCGGCTACCGTCTGATCCCGCTGGTGG
ACCGCACCCAGGACGGCGAGTTGCTGCGCCGCATCCGCGGCATCCGCAAGAAGATCGCCCAGGATCTGGGCTTCCTGGTG
CCGCCGGTCCATATCCGCGACAATCTGGAAATCAAGCCCAATGCCTACCGCATCCTGCTCAAGGGCGTGGAGCTGGGCAA
GGGCGAAGCCTTCATCGGCCAGTTCCTGGCCATCAATCCGGGCATGGTCAGCAAGGAGATCGCCGGCGCCGCCACCACCG
ATCCCGCCTTCGGCCTGCCGGCGGTGTGGATAGACGCCGGCAAGCGCGAAGAGGCGCAAAGCCTGGGCTATACCGTGGTC
GACGCCAGCACCGTGGTCGCCACCCACATCTCCAACCTGCTGCAGACCCACTCCGCCGAGCTGCTGGGACGCGAGGAAGT
GCAGGCGCTGATCGACCACCAGGCCAAGGAATCGCCGAAGCTGATCGAGGACCTGGTGCCCAAGGTGGTGCCGGTGAGCA
TATTGCAGAAAGTGCTGCAGCAGCTGCTGTCGGAAGGCATACACATCCGCGACTTCCGCACCATCGTCGAAACGCTGGCA
GACCATGTGCCTCAAAACCAGGACATCGACGAGCTGACCAGCGCGGTGCGCACCGCGCTGTCGCGCGTGATCGTCCAGCA
GCTGTTCCCCGGCGAGGCGGAACTGCCGCTGATGACGCTGGAGCCGGCGCTGGAGAACGTGCTGATGCAGGCGGTGCAGT
CCAAGGCCGGGGGCGGGCTGGAGCCCGGGCTGGCGGAAAATCTGCTGTCCAGCGCCGCCCAGCAGACGGAACAAGTGGAG
ATCCAGGGATACAATCCGGTGCTGCTCACGGCGCCGGGGCTGCGGCCGCTGCTGGCGCGTTTCCTGCGCCGGGCATTGCC
GCAGTTGCGCGTGATTTCGCATAATGAGATTCCGGACAATAAATCCATTCGTATAATTGCGGTAATCGGCGGCAGCAAGG
GCTAA

Upstream 100 bases:

>100_bases
GGCCCCGGTGTATCCGGACCAATTGGACGTGCCCGACGAGCTTGACCCGTACAGCAAACGTCCGCAAGATTCGGCGCCAG
AAGAAAGCCGATAAGCCAGC

Downstream 100 bases:

>100_bases
GGGCTAATCGACAATGGTGGTGAAAAAGTTCTTCGGGAAAACCACTCGAGACGCACTCCGGCAAGTTCGCGAAGAACTGG
GTGCGGACGCCCTCATTTTG

Product: flagellar biosynthesis protein flhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MDSILQILRTMKITQLAGPLLIILILMMMILPLPPVLLDIFFTFNIAVSVIVLLVGINVRKPLDFSSFPSVLLITTMLRL
SLNVASSRVVLLEGHTGPDAAGKVIESFSHFLVGGNVAIGIVVFIIITIINFVVITKGAGRIAEVSARFTLDAMPGKQMA
IDADLNAGLIGEDEARKRRSTIAEEANFFGAMDGASKYVRGDAMAGILIILINVIGGLIVGVVQHDLPVGQAAETYTLLS
IGDGLVAQIPALIISTAAGIVVTRVGTDQDMSEQFLGQLFTKPQVLYITSAVIGMIGLIPNMPHFAFLLIAGSLLALARG
MERRNRLRREKELQAAVQPAAAPEQQAAEVGWHDVQHVDQLGMEVGYRLIPLVDRTQDGELLRRIRGIRKKIAQDLGFLV
PPVHIRDNLEIKPNAYRILLKGVELGKGEAFIGQFLAINPGMVSKEIAGAATTDPAFGLPAVWIDAGKREEAQSLGYTVV
DASTVVATHISNLLQTHSAELLGREEVQALIDHQAKESPKLIEDLVPKVVPVSILQKVLQQLLSEGIHIRDFRTIVETLA
DHVPQNQDIDELTSAVRTALSRVIVQQLFPGEAELPLMTLEPALENVLMQAVQSKAGGGLEPGLAENLLSSAAQQTEQVE
IQGYNPVLLTAPGLRPLLARFLRRALPQLRVISHNEIPDNKSIRIIAVIGGSKG

Sequences:

>Translated_694_residues
MDSILQILRTMKITQLAGPLLIILILMMMILPLPPVLLDIFFTFNIAVSVIVLLVGINVRKPLDFSSFPSVLLITTMLRL
SLNVASSRVVLLEGHTGPDAAGKVIESFSHFLVGGNVAIGIVVFIIITIINFVVITKGAGRIAEVSARFTLDAMPGKQMA
IDADLNAGLIGEDEARKRRSTIAEEANFFGAMDGASKYVRGDAMAGILIILINVIGGLIVGVVQHDLPVGQAAETYTLLS
IGDGLVAQIPALIISTAAGIVVTRVGTDQDMSEQFLGQLFTKPQVLYITSAVIGMIGLIPNMPHFAFLLIAGSLLALARG
MERRNRLRREKELQAAVQPAAAPEQQAAEVGWHDVQHVDQLGMEVGYRLIPLVDRTQDGELLRRIRGIRKKIAQDLGFLV
PPVHIRDNLEIKPNAYRILLKGVELGKGEAFIGQFLAINPGMVSKEIAGAATTDPAFGLPAVWIDAGKREEAQSLGYTVV
DASTVVATHISNLLQTHSAELLGREEVQALIDHQAKESPKLIEDLVPKVVPVSILQKVLQQLLSEGIHIRDFRTIVETLA
DHVPQNQDIDELTSAVRTALSRVIVQQLFPGEAELPLMTLEPALENVLMQAVQSKAGGGLEPGLAENLLSSAAQQTEQVE
IQGYNPVLLTAPGLRPLLARFLRRALPQLRVISHNEIPDNKSIRIIAVIGGSKG
>Mature_694_residues
MDSILQILRTMKITQLAGPLLIILILMMMILPLPPVLLDIFFTFNIAVSVIVLLVGINVRKPLDFSSFPSVLLITTMLRL
SLNVASSRVVLLEGHTGPDAAGKVIESFSHFLVGGNVAIGIVVFIIITIINFVVITKGAGRIAEVSARFTLDAMPGKQMA
IDADLNAGLIGEDEARKRRSTIAEEANFFGAMDGASKYVRGDAMAGILIILINVIGGLIVGVVQHDLPVGQAAETYTLLS
IGDGLVAQIPALIISTAAGIVVTRVGTDQDMSEQFLGQLFTKPQVLYITSAVIGMIGLIPNMPHFAFLLIAGSLLALARG
MERRNRLRREKELQAAVQPAAAPEQQAAEVGWHDVQHVDQLGMEVGYRLIPLVDRTQDGELLRRIRGIRKKIAQDLGFLV
PPVHIRDNLEIKPNAYRILLKGVELGKGEAFIGQFLAINPGMVSKEIAGAATTDPAFGLPAVWIDAGKREEAQSLGYTVV
DASTVVATHISNLLQTHSAELLGREEVQALIDHQAKESPKLIEDLVPKVVPVSILQKVLQQLLSEGIHIRDFRTIVETLA
DHVPQNQDIDELTSAVRTALSRVIVQQLFPGEAELPLMTLEPALENVLMQAVQSKAGGGLEPGLAENLLSSAAQQTEQVE
IQGYNPVLLTAPGLRPLLARFLRRALPQLRVISHNEIPDNKSIRIIAVIGGSKG

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=694, Percent_Identity=59.6541786743516, Blast_Score=808, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74906; Mature: 74906

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSILQILRTMKITQLAGPLLIILILMMMILPLPPVLLDIFFTFNIAVSVIVLLVGINVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KPLDFSSFPSVLLITTMLRLSLNVASSRVVLLEGHTGPDAAGKVIESFSHFLVGGNVAIG
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHH
IVVFIIITIINFVVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIGEDEARKRRS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHHHHHHHH
TIAEEANFFGAMDGASKYVRGDAMAGILIILINVIGGLIVGVVQHDLPVGQAAETYTLLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
IGDGLVAQIPALIISTAAGIVVTRVGTDQDMSEQFLGQLFTKPQVLYITSAVIGMIGLIP
CCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
NMPHFAFLLIAGSLLALARGMERRNRLRREKELQAAVQPAAAPEQQAAEVGWHDVQHVDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHH
LGMEVGYRLIPLVDRTQDGELLRRIRGIRKKIAQDLGFLVPPVHIRDNLEIKPNAYRILL
HHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEECCCHHEEEE
KGVELGKGEAFIGQFLAINPGMVSKEIAGAATTDPAFGLPAVWIDAGKREEAQSLGYTVV
ECCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCEEEE
DASTVVATHISNLLQTHSAELLGREEVQALIDHQAKESPKLIEDLVPKVVPVSILQKVLQ
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QLLSEGIHIRDFRTIVETLADHVPQNQDIDELTSAVRTALSRVIVQQLFPGEAELPLMTL
HHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEH
EPALENVLMQAVQSKAGGGLEPGLAENLLSSAAQQTEQVEIQGYNPVLLTAPGLRPLLAR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEECCCHHHHHHH
FLRRALPQLRVISHNEIPDNKSIRIIAVIGGSKG
HHHHHHHHHEECCCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MDSILQILRTMKITQLAGPLLIILILMMMILPLPPVLLDIFFTFNIAVSVIVLLVGINVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KPLDFSSFPSVLLITTMLRLSLNVASSRVVLLEGHTGPDAAGKVIESFSHFLVGGNVAIG
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHH
IVVFIIITIINFVVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIGEDEARKRRS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHHHHHHHH
TIAEEANFFGAMDGASKYVRGDAMAGILIILINVIGGLIVGVVQHDLPVGQAAETYTLLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
IGDGLVAQIPALIISTAAGIVVTRVGTDQDMSEQFLGQLFTKPQVLYITSAVIGMIGLIP
CCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
NMPHFAFLLIAGSLLALARGMERRNRLRREKELQAAVQPAAAPEQQAAEVGWHDVQHVDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHH
LGMEVGYRLIPLVDRTQDGELLRRIRGIRKKIAQDLGFLVPPVHIRDNLEIKPNAYRILL
HHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEECCCHHEEEE
KGVELGKGEAFIGQFLAINPGMVSKEIAGAATTDPAFGLPAVWIDAGKREEAQSLGYTVV
ECCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCEEEE
DASTVVATHISNLLQTHSAELLGREEVQALIDHQAKESPKLIEDLVPKVVPVSILQKVLQ
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QLLSEGIHIRDFRTIVETLADHVPQNQDIDELTSAVRTALSRVIVQQLFPGEAELPLMTL
HHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEH
EPALENVLMQAVQSKAGGGLEPGLAENLLSSAAQQTEQVEIQGYNPVLLTAPGLRPLLAR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCEEEEECCCHHHHHHH
FLRRALPQLRVISHNEIPDNKSIRIIAVIGGSKG
HHHHHHHHHEECCCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]