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The map label for this gene is aroQ

Identifier: 34496442

GI number: 34496442

Start: 1023648

End: 1024118

Strand: Reverse

Name: aroQ

Synonym: CV_0987

Alternate gene names: 34496442

Gene position: 1024118-1023648 (Counterclockwise)

Preceding gene: 34496445

Following gene: 34496441

Centisome position: 21.56

GC content: 61.78

Gene sequence:

>471_bases
ATGAAAAACAGGAGCCTGGCCTTGAGCCAATCCATCCTCGTGCTGCACGGCCCCAACCTCAATCTTCTCGGGGTGCGGGA
ACCACAACACTACGGCCGGGACACCCTTGACGACATCAACCGGCGGCTGACTCAGCAAGCCAAGGCGGCGGGCTTTTCCC
TGTCCGCGCTGCAGAGCAACGCCGAACACATACTGATAGAACGCATACACCAATGCCTGGATGACGGCACCGCCTTCATC
CTGATCAATCCGGCGGCGTTCACCCACACCAGCGTCGCGCTGCGCGACGCGCTGGCCGCGGTGAAGGTTCCGTTCATTGA
AGTACATCTATCCAACGTCCACGCCCGCGAACCGTTCCGCCAGCACTCGTACTTTTCCGATCTGGCGCTCGGCGTAATCT
GCGGTCTGGGCGCCCATGGCTACGAACTGGCGCTTGCGCACGCGATGCGACACCTGTCCGCGCAAGCCTGA

Upstream 100 bases:

>100_bases
AACAGGCGCAGCGATGCGCGCCGCGGCGCAGCAAACGACCGTTTTAAATTCCGCAAATGCTGGACATCTTGCGGCGAATT
GCGGCAAACTCGCGGCCAAG

Downstream 100 bases:

>100_bases
CCATCGTTACAGAACATCCAATCGAAGGATCGACAATGGACCTGCGTAAACTGAAAAAACTGATCGACCTGGTCGAAGAG
TCCGGCATCGCCGAACTGGA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKNRSLALSQSILVLHGPNLNLLGVREPQHYGRDTLDDINRRLTQQAKAAGFSLSALQSNAEHILIERIHQCLDDGTAFI
LINPAAFTHTSVALRDALAAVKVPFIEVHLSNVHAREPFRQHSYFSDLALGVICGLGAHGYELALAHAMRHLSAQA

Sequences:

>Translated_156_residues
MKNRSLALSQSILVLHGPNLNLLGVREPQHYGRDTLDDINRRLTQQAKAAGFSLSALQSNAEHILIERIHQCLDDGTAFI
LINPAAFTHTSVALRDALAAVKVPFIEVHLSNVHAREPFRQHSYFSDLALGVICGLGAHGYELALAHAMRHLSAQA
>Mature_156_residues
MKNRSLALSQSILVLHGPNLNLLGVREPQHYGRDTLDDINRRLTQQAKAAGFSLSALQSNAEHILIERIHQCLDDGTAFI
LINPAAFTHTSVALRDALAAVKVPFIEVHLSNVHAREPFRQHSYFSDLALGVICGLGAHGYELALAHAMRHLSAQA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_CHRVO (Q7NZD5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900657.1
- ProteinModelPortal:   Q7NZD5
- SMR:   Q7NZD5
- GeneID:   2550916
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_0987
- NMPDR:   fig|243365.1.peg.987
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   CVIO243365:CV_0987-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 17088; Mature: 17088

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 31-31 ACT_SITE 109-109 BINDING 83-83 BINDING 89-89 BINDING 96-96 BINDING 120-120

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRSLALSQSILVLHGPNLNLLGVREPQHYGRDTLDDINRRLTQQAKAAGFSLSALQSN
CCCCCCEECCCEEEEECCCCCEEECCCCHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCC
AEHILIERIHQCLDDGTAFILINPAAFTHTSVALRDALAAVKVPFIEVHLSNVHAREPFR
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHH
QHSYFSDLALGVICGLGAHGYELALAHAMRHLSAQA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNRSLALSQSILVLHGPNLNLLGVREPQHYGRDTLDDINRRLTQQAKAAGFSLSALQSN
CCCCCCEECCCEEEEECCCCCEEECCCCHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCC
AEHILIERIHQCLDDGTAFILINPAAFTHTSVALRDALAAVKVPFIEVHLSNVHAREPFR
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHH
QHSYFSDLALGVICGLGAHGYELALAHAMRHLSAQA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782