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The map label for this gene is ybeC [H]

Identifier: 34496326

GI number: 34496326

Start: 898556

End: 900208

Strand: Reverse

Name: ybeC [H]

Synonym: CV_0871

Alternate gene names: 34496326

Gene position: 900208-898556 (Counterclockwise)

Preceding gene: 34496329

Following gene: 34496324

Centisome position: 18.95

GC content: 67.09

Gene sequence:

>1653_bases
ATGACTGGAGATTCGCCCTTGCAACAACAACACTCCCGCCACATCGGTCCGATCGCGCTGATGCTGACCGGCCTTGGCTC
CATCATCGGTTCCGGCTGGCTGTTCGGCGCCGCCCACGCGGCGCAGATCGCCGGCCCGGCCGCCATCGTCGCCTGGATTG
TCGGCATGGTGATCATTCTTTCCATCGCGCTGAGCTACGCCGAACTGGGCGCCATGTTCCCGGAATCGGGCGGCATGGTG
CGCTACGCCCGCTACTCGCATGGCTCGCTGCTCGGCTTCATCGCCGCCTGGGCCAACTGGATCGCCATCGTGTCGGTGAT
TCCGATCGAGGCCGAAGCCTCGGTGCAGTACATGAGCACCTGGCCCTATCCGTGGGCGCAGAACCTGTACCACAACGGCG
AGCTGAGCACCGTCGGCCTGTCCTTCGCCGCCGTGCTGGTGATCGCCTACTTCCTGCTCAACTACTGGGGCGTGAAACTG
TTCGCCAAGGCCAACAGCGCCATCACCATCTTCAAGGTGATCGTGCCGGCGGTGACCGTGGGCGCGCTGATCTACAGCGG
CTTCCACTCGGAGAACCTGAACAACCCGGCGATGGGCGGCTTCGCGCCGTTCGGCTGGGCCAGCGTGATGACGGCGGTGG
CCACCAGCGGCATCGTGTTCAGCTTCAACGGCTTCCAAAGCCCGATCAACCTGGCCGGCGAAGCCCGCAATCCGGGCAAG
AGCGTGCCCTTCGGCGTGGTCGGCTCCATCCTGCTGGCCGCGGTGATCTACGTCGCGCTGCAGGTCGCCTTCCTGGGCGC
GCTGTCGCCGTCCGAGCTGGCGCACGGCTGGAAAGGCCTGGACTTCAGCTCGCCGTTCGCGCAGCTGGCGATGGCGCTGG
GCCTGAACTGGCTGATGATGACCCTGTATTTCGACGCCTTCGTCAGCCCCAGCGGCACCGGCGCCACCTATATGGCGTCC
ACCTCGCGCATGATCTACGGCATGCAGCGCAACGGCACCATGCCGGAGATCTTCGGCCGCATCCACCCGCTGTACCGCAT
TCCGCGCCCGGCGATGTGGTTCAACCTGGCGGTGTCCTTCGTGTTCCTGTTCTTCTTCCGCGGCTGGGGCACGCTGGCGG
CGGTGATCTCGGTCGCCACCGTGATCTCCTACCTGACCGGCCCGATCAGCGCCGCCGCGCTGCGCCGCTGTGCGCCGGAT
CTGCCGCGCCCGCTGCGCCTGGCCGGCCTGTCGGTGGTCGCGCCGTTCGCCTTCGTCTGCGCGTCGCTGGTGCTGTACTG
GGCGCGCTGGCCGCTGACCGGCCAGATCCTGTTCCTGATCGTGGCCGCGCTGCCGGTCTACATCTGGTACCAGGCCAAGG
CCGGCTGGCCCGAATTCGCCCGCGAGCTGAAGGGCGCGCTGTGGATGGTGCTCTACCTGCCGGCGATGGCGCTGCTGTCC
TATATCGGCAGCGTCGACTTCGGCGGCATCGGCCTGCTGCCGTACGGCGTCGACATGGCCGTGGTGGCCGCGGCCTCGCT
GGGCTTCTACTTCTGGGGCGTCAACAGCGGCTGGTACACCCGCTACCTGCGCGACGAGCACGACCCGAAACTGGTGGAGG
CGATGCAGCAGGAAGCCAAGGCATCCGGCAAGCTGGCTGAGCAGCGCGGCTGA

Upstream 100 bases:

>100_bases
TACATAAGACCGGGCCCACCCGGCTATGTGGGCAACTTCCTCCAGGCACGTCCGGCGCGTGCGCGCCGCCGCGGGAGAGT
CGTTGCCCGTCATCGTTCAA

Downstream 100 bases:

>100_bases
GCGCGCCGGTCCCGCATGCGAAAAAGCCGACCTCGCGGTCGGCTTTTTCTTTGCCTGCGACAAATGGCTTGCCGCGTTAC
AGCGCCGCCAGGGCGGCTGC

Product: amino-acid permease transmembrane protein

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTGDSPLQQQHSRHIGPIALMLTGLGSIIGSGWLFGAAHAAQIAGPAAIVAWIVGMVIILSIALSYAELGAMFPESGGMV
RYARYSHGSLLGFIAAWANWIAIVSVIPIEAEASVQYMSTWPYPWAQNLYHNGELSTVGLSFAAVLVIAYFLLNYWGVKL
FAKANSAITIFKVIVPAVTVGALIYSGFHSENLNNPAMGGFAPFGWASVMTAVATSGIVFSFNGFQSPINLAGEARNPGK
SVPFGVVGSILLAAVIYVALQVAFLGALSPSELAHGWKGLDFSSPFAQLAMALGLNWLMMTLYFDAFVSPSGTGATYMAS
TSRMIYGMQRNGTMPEIFGRIHPLYRIPRPAMWFNLAVSFVFLFFFRGWGTLAAVISVATVISYLTGPISAAALRRCAPD
LPRPLRLAGLSVVAPFAFVCASLVLYWARWPLTGQILFLIVAALPVYIWYQAKAGWPEFARELKGALWMVLYLPAMALLS
YIGSVDFGGIGLLPYGVDMAVVAAASLGFYFWGVNSGWYTRYLRDEHDPKLVEAMQQEAKASGKLAEQRG

Sequences:

>Translated_550_residues
MTGDSPLQQQHSRHIGPIALMLTGLGSIIGSGWLFGAAHAAQIAGPAAIVAWIVGMVIILSIALSYAELGAMFPESGGMV
RYARYSHGSLLGFIAAWANWIAIVSVIPIEAEASVQYMSTWPYPWAQNLYHNGELSTVGLSFAAVLVIAYFLLNYWGVKL
FAKANSAITIFKVIVPAVTVGALIYSGFHSENLNNPAMGGFAPFGWASVMTAVATSGIVFSFNGFQSPINLAGEARNPGK
SVPFGVVGSILLAAVIYVALQVAFLGALSPSELAHGWKGLDFSSPFAQLAMALGLNWLMMTLYFDAFVSPSGTGATYMAS
TSRMIYGMQRNGTMPEIFGRIHPLYRIPRPAMWFNLAVSFVFLFFFRGWGTLAAVISVATVISYLTGPISAAALRRCAPD
LPRPLRLAGLSVVAPFAFVCASLVLYWARWPLTGQILFLIVAALPVYIWYQAKAGWPEFARELKGALWMVLYLPAMALLS
YIGSVDFGGIGLLPYGVDMAVVAAASLGFYFWGVNSGWYTRYLRDEHDPKLVEAMQQEAKASGKLAEQRG
>Mature_549_residues
TGDSPLQQQHSRHIGPIALMLTGLGSIIGSGWLFGAAHAAQIAGPAAIVAWIVGMVIILSIALSYAELGAMFPESGGMVR
YARYSHGSLLGFIAAWANWIAIVSVIPIEAEASVQYMSTWPYPWAQNLYHNGELSTVGLSFAAVLVIAYFLLNYWGVKLF
AKANSAITIFKVIVPAVTVGALIYSGFHSENLNNPAMGGFAPFGWASVMTAVATSGIVFSFNGFQSPINLAGEARNPGKS
VPFGVVGSILLAAVIYVALQVAFLGALSPSELAHGWKGLDFSSPFAQLAMALGLNWLMMTLYFDAFVSPSGTGATYMAST
SRMIYGMQRNGTMPEIFGRIHPLYRIPRPAMWFNLAVSFVFLFFFRGWGTLAAVISVATVISYLTGPISAAALRRCAPDL
PRPLRLAGLSVVAPFAFVCASLVLYWARWPLTGQILFLIVAALPVYIWYQAKAGWPEFARELKGALWMVLYLPAMALLSY
IGSVDFGGIGLLPYGVDMAVVAAASLGFYFWGVNSGWYTRYLRDEHDPKLVEAMQQEAKASGKLAEQRG

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=410, Percent_Identity=24.390243902439, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI33286428, Length=455, Percent_Identity=24.6153846153846, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI110347453, Length=363, Percent_Identity=25.3443526170799, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI114326544, Length=430, Percent_Identity=23.4883720930233, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI114326550, Length=430, Percent_Identity=23.4883720930233, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI115648063, Length=421, Percent_Identity=23.9904988123515, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI115648022, Length=421, Percent_Identity=23.9904988123515, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI258614005, Length=421, Percent_Identity=24.2280285035629, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI258614003, Length=421, Percent_Identity=24.2280285035629, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI186910308, Length=440, Percent_Identity=24.3181818181818, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI186910306, Length=440, Percent_Identity=24.3181818181818, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI186910304, Length=440, Percent_Identity=24.3181818181818, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI258645169, Length=421, Percent_Identity=23.7529691211401, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI187423910, Length=472, Percent_Identity=21.6101694915254, Blast_Score=66, Evalue=9e-11,
Organism=Homo sapiens, GI7657591, Length=472, Percent_Identity=21.6101694915254, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1786789, Length=400, Percent_Identity=26.25, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082250, Length=475, Percent_Identity=24.6315789473684, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786302, Length=409, Percent_Identity=26.161369193154, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367353, Length=352, Percent_Identity=26.1363636363636, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788480, Length=361, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786602, Length=364, Percent_Identity=26.3736263736264, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081869, Length=308, Percent_Identity=23.3766233766234, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789017, Length=344, Percent_Identity=24.4186046511628, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081915, Length=352, Percent_Identity=25.5681818181818, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081708, Length=350, Percent_Identity=22.8571428571429, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87082023, Length=309, Percent_Identity=25.5663430420712, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI48994972, Length=355, Percent_Identity=26.1971830985915, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790653, Length=349, Percent_Identity=22.0630372492837, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32566699, Length=328, Percent_Identity=26.5243902439024, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=445, Percent_Identity=23.5955056179775, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531343, Length=427, Percent_Identity=25.2927400468384, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17532491, Length=404, Percent_Identity=23.019801980198, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=424, Percent_Identity=24.2924528301887, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71993915, Length=384, Percent_Identity=24.7395833333333, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24651635, Length=463, Percent_Identity=25.0539956803456, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24651633, Length=463, Percent_Identity=25.0539956803456, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24667468, Length=425, Percent_Identity=25.6470588235294, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221331183, Length=465, Percent_Identity=25.1612903225806, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17647653, Length=465, Percent_Identity=25.1612903225806, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24664379, Length=465, Percent_Identity=25.1612903225806, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357367, Length=448, Percent_Identity=26.7857142857143, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221512776, Length=370, Percent_Identity=23.2432432432432, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24666159, Length=371, Percent_Identity=23.1805929919137, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45550968, Length=419, Percent_Identity=23.8663484486874, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921172, Length=419, Percent_Identity=23.8663484486874, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 59302; Mature: 59171

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDSPLQQQHSRHIGPIALMLTGLGSIIGSGWLFGAAHAAQIAGPAAIVAWIVGMVIIL
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SIALSYAELGAMFPESGGMVRYARYSHGSLLGFIAAWANWIAIVSVIPIEAEASVQYMST
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHCC
WPYPWAQNLYHNGELSTVGLSFAAVLVIAYFLLNYWGVKLFAKANSAITIFKVIVPAVTV
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHH
GALIYSGFHSENLNNPAMGGFAPFGWASVMTAVATSGIVFSFNGFQSPINLAGEARNPGK
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHCCCCCCCCCC
SVPFGVVGSILLAAVIYVALQVAFLGALSPSELAHGWKGLDFSSPFAQLAMALGLNWLMM
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TLYFDAFVSPSGTGATYMASTSRMIYGMQRNGTMPEIFGRIHPLYRIPRPAMWFNLAVSF
HHHHHHHCCCCCCCCEEEECCCHHEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VFLFFFRGWGTLAAVISVATVISYLTGPISAAALRRCAPDLPRPLRLAGLSVVAPFAFVC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ASLVLYWARWPLTGQILFLIVAALPVYIWYQAKAGWPEFARELKGALWMVLYLPAMALLS
HHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YIGSVDFGGIGLLPYGVDMAVVAAASLGFYFWGVNSGWYTRYLRDEHDPKLVEAMQQEAK
HHCCCCCCCEECCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHCCCCCHHHHHHHHHHHH
ASGKLAEQRG
HCCCHHHCCC
>Mature Secondary Structure 
TGDSPLQQQHSRHIGPIALMLTGLGSIIGSGWLFGAAHAAQIAGPAAIVAWIVGMVIIL
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SIALSYAELGAMFPESGGMVRYARYSHGSLLGFIAAWANWIAIVSVIPIEAEASVQYMST
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHCC
WPYPWAQNLYHNGELSTVGLSFAAVLVIAYFLLNYWGVKLFAKANSAITIFKVIVPAVTV
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHH
GALIYSGFHSENLNNPAMGGFAPFGWASVMTAVATSGIVFSFNGFQSPINLAGEARNPGK
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHCCCCCCCCCC
SVPFGVVGSILLAAVIYVALQVAFLGALSPSELAHGWKGLDFSSPFAQLAMALGLNWLMM
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TLYFDAFVSPSGTGATYMASTSRMIYGMQRNGTMPEIFGRIHPLYRIPRPAMWFNLAVSF
HHHHHHHCCCCCCCCEEEECCCHHEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VFLFFFRGWGTLAAVISVATVISYLTGPISAAALRRCAPDLPRPLRLAGLSVVAPFAFVC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ASLVLYWARWPLTGQILFLIVAALPVYIWYQAKAGWPEFARELKGALWMVLYLPAMALLS
HHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YIGSVDFGGIGLLPYGVDMAVVAAASLGFYFWGVNSGWYTRYLRDEHDPKLVEAMQQEAK
HHCCCCCCCEECCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHCCCCCHHHHHHHHHHHH
ASGKLAEQRG
HCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]