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The map label for this gene is aroB

Identifier: 34496282

GI number: 34496282

Start: 854392

End: 855471

Strand: Reverse

Name: aroB

Synonym: CV_0827

Alternate gene names: 34496282

Gene position: 855471-854392 (Counterclockwise)

Preceding gene: 34496283

Following gene: 34496281

Centisome position: 18.01

GC content: 67.13

Gene sequence:

>1080_bases
GTGATCACCCTCGACCTGATCCTGCCCGACACCCGATACCCGATACACATTGGCCACGGACTTCTGGAACAGGTCGACCT
GCTGCTACCCCACCTGCCGCTGCCCAAGGCGGCCATCGTCAGCAACGCCACCGTGGCCCCGCTGTACCTGCAGCGGCTGC
AACAGGCGCTGGAAGCGCGCGGCGTGGCCTGCTCCAGCGTAGTGCTGCCCGACGGCGAGCAGCACAAGGACTGGCAGACG
CTCAACCTGATCTTCGACGCGCTGCTGTCCGGCAACGCCGAGCGCAAGACCACGCTGATCGCGCTGGGCGGAGGCGTGAT
CGGCGACATGACCGGCTTCGCCGCCGCCTGCTACCAGCGCGGCGCGCCCTTCATCCAGATTCCCACCACGCTGCTCGCCC
AGGTGGACTCCTCGGTCGGCGGCAAGACCGCGATCAACCACCCGCTGGGCAAGAACATGATAGGCGCCTTCTACCAGCCC
AAAGCGGTGATCGCGGACATGGAGCTGCTCGCCACGCTGCCCGACCGCGAACTATCGGCCGGCTTGGCCGAGGTGATCAA
ATACGGCCTGCTCGGCGACGCCGGCTTCCTCGCCTGGCTGGAAGCCAATATGGCCAAGCTGCGCGCGCGCGACGGCGACG
CGCTGCAGTACGCGGTGAAACGCAGCTGCGAAATGAAGGCCGCCATCGTCGCCGAGGACGAAAAGGAAAACGGCGTTCGC
GCGCTCCTGAACCTGGGCCATACCTTCGGCCACGCCATCGAGGCGGGCATGGGCTACGGCGCCTGGCTGCACGGCGAAGC
GGTGGCTGCCGGCATGGTTCTGGCCGCGGCGGCGTCCGCCGAGCTCGGCTGGATCGGCCGGGACGAGGCCGAACGCGTGC
GTCGGCTGATCGCCGCCGCCGGACTGCCGGTCAAGGCGCCCTCCATGCCAACCGAACAATGGCTGAACCTGATGAGCCAC
GACAAGAAGGTGGAGGCGGGCACCGTGCGCTTCGTATTGTTGCGCGAGCTGGGCCAGGCCGTGATAAAGTCGGGGTTGGA
CACCGCCTTGCTGGACAAGATTCTGCGCGAAAACAGCTGA

Upstream 100 bases:

>100_bases
ACATCATCATCGACACCACCCAGCAGAACGTCAATCTGCTGGTCGGCCGTCTGGTCGACCAGTTGTTGGACTCCCCGCAC
CATCCCAAGGAAACCGACTA

Downstream 100 bases:

>100_bases
TCTCCGGCTGTCCGGGTGGCCGGGCTACGGATTTATACGCATTGCCAAGCCACCCGCCTCGTCAGAATAATCAACAGACT
AAATAAGATGTTGTTTCACA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MITLDLILPDTRYPIHIGHGLLEQVDLLLPHLPLPKAAIVSNATVAPLYLQRLQQALEARGVACSSVVLPDGEQHKDWQT
LNLIFDALLSGNAERKTTLIALGGGVIGDMTGFAAACYQRGAPFIQIPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQP
KAVIADMELLATLPDRELSAGLAEVIKYGLLGDAGFLAWLEANMAKLRARDGDALQYAVKRSCEMKAAIVAEDEKENGVR
ALLNLGHTFGHAIEAGMGYGAWLHGEAVAAGMVLAAAASAELGWIGRDEAERVRRLIAAAGLPVKAPSMPTEQWLNLMSH
DKKVEAGTVRFVLLRELGQAVIKSGLDTALLDKILRENS

Sequences:

>Translated_359_residues
MITLDLILPDTRYPIHIGHGLLEQVDLLLPHLPLPKAAIVSNATVAPLYLQRLQQALEARGVACSSVVLPDGEQHKDWQT
LNLIFDALLSGNAERKTTLIALGGGVIGDMTGFAAACYQRGAPFIQIPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQP
KAVIADMELLATLPDRELSAGLAEVIKYGLLGDAGFLAWLEANMAKLRARDGDALQYAVKRSCEMKAAIVAEDEKENGVR
ALLNLGHTFGHAIEAGMGYGAWLHGEAVAAGMVLAAAASAELGWIGRDEAERVRRLIAAAGLPVKAPSMPTEQWLNLMSH
DKKVEAGTVRFVLLRELGQAVIKSGLDTALLDKILRENS
>Mature_359_residues
MITLDLILPDTRYPIHIGHGLLEQVDLLLPHLPLPKAAIVSNATVAPLYLQRLQQALEARGVACSSVVLPDGEQHKDWQT
LNLIFDALLSGNAERKTTLIALGGGVIGDMTGFAAACYQRGAPFIQIPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQP
KAVIADMELLATLPDRELSAGLAEVIKYGLLGDAGFLAWLEANMAKLRARDGDALQYAVKRSCEMKAAIVAEDEKENGVR
ALLNLGHTFGHAIEAGMGYGAWLHGEAVAAGMVLAAAASAELGWIGRDEAERVRRLIAAAGLPVKAPSMPTEQWLNLMSH
DKKVEAGTVRFVLLRELGQAVIKSGLDTALLDKILRENS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=347, Percent_Identity=55.3314121037464, Blast_Score=364, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6320332, Length=373, Percent_Identity=35.9249329758713, Blast_Score=207, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_CHRVO (Q7NZU4)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900497.1
- ProteinModelPortal:   Q7NZU4
- SMR:   Q7NZU4
- GeneID:   2549256
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_0827
- NMPDR:   fig|243365.1.peg.827
- HOGENOM:   HBG632303
- OMA:   EHAIATS
- PhylomeDB:   Q7NZU4
- ProtClustDB:   PRK00002
- BioCyc:   CVIO243365:CV_0827-MONOMER
- BRENDA:   4.2.3.4
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38343; Mature: 38343

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLDLILPDTRYPIHIGHGLLEQVDLLLPHLPLPKAAIVSNATVAPLYLQRLQQALEAR
CEEEEEEECCCCCCEECCHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHC
GVACSSVVLPDGEQHKDWQTLNLIFDALLSGNAERKTTLIALGGGVIGDMTGFAAACYQR
CCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GAPFIQIPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQPKAVIADMELLATLPDRELSA
CCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
GLAEVIKYGLLGDAGFLAWLEANMAKLRARDGDALQYAVKRSCEMKAAIVAEDEKENGVR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALLNLGHTFGHAIEAGMGYGAWLHGEAVAAGMVLAAAASAELGWIGRDEAERVRRLIAAA
HHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
GLPVKAPSMPTEQWLNLMSHDKKVEAGTVRFVLLRELGQAVIKSGLDTALLDKILRENS
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MITLDLILPDTRYPIHIGHGLLEQVDLLLPHLPLPKAAIVSNATVAPLYLQRLQQALEAR
CEEEEEEECCCCCCEECCHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHC
GVACSSVVLPDGEQHKDWQTLNLIFDALLSGNAERKTTLIALGGGVIGDMTGFAAACYQR
CCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GAPFIQIPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQPKAVIADMELLATLPDRELSA
CCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
GLAEVIKYGLLGDAGFLAWLEANMAKLRARDGDALQYAVKRSCEMKAAIVAEDEKENGVR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALLNLGHTFGHAIEAGMGYGAWLHGEAVAAGMVLAAAASAELGWIGRDEAERVRRLIAAA
HHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
GLPVKAPSMPTEQWLNLMSHDKKVEAGTVRFVLLRELGQAVIKSGLDTALLDKILRENS
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782