Click here to switch to the map view.

The map label for this gene is thrB [H]

Identifier: 34496231

GI number: 34496231

Start: 800260

End: 801201

Strand: Reverse

Name: thrB [H]

Synonym: CV_0776

Alternate gene names: 34496231

Gene position: 801201-800260 (Counterclockwise)

Preceding gene: 34496232

Following gene: 34496230

Centisome position: 16.86

GC content: 63.59

Gene sequence:

>942_bases
ATGTCGGTTTACACCACGGTCAGCCGGGAATCGTTGCAACACTGGCTGCAGGGCTACGCGCTGGGGCAATTGCTTGAGCT
GAAAGGCATTGCGGCGGGCATCACCAATACCAACTACTTCGTCACCACCACGCATGGCCGCTACGTGCTGACGCTGTTCG
AAACGCTGCATCTGGACGAGTTGCCCTACTACCTGACGCTGATGAGCCACCTGGCCAAACACGGCGTCGCCTGCCCTGCG
CCAGTCGCCGACCACACCGACCGCTTCGCGTCGACGCTGGCCGGCAAGCCGGCCTGCCTGGTCAGCTGCCTCGGGGGACA
AGACGTCAGCCACCCCAGCGCGGAGCAATGCCGCGCAGTCGGCGAAACGCTGGCCCAGATGCACAAGGCCGGCGCCACCT
TCCCGCTGCAGATGAAGAACCCGCGCGGCCCGCGCTGGTGGAGCCGGACCGCGCAGCAGCTGTATCCGCAGCTGCCCGCC
GATCAGGCCGAACTGCTGCGGGAGGAAATACAGTTCCAGGACAGTCACCGCTTCGATCACCTGCCCAGCGGCGTGATCCA
TGCCGACCTGTTCCGGGACAATGTTTTGTTGAATGGAAACCACATCAGCGGCTTCATCGACTTCTACTACGCCTGCAACG
ACATCCTGTTGTACGACGTGGCCATCGCGGTCAACGACTGGGCGCGGCTTGACGACGGCGAACTCGATGGCGGACTGGCC
AAAGCCTTTCTCGAAGGCTATCAATCGGAAAGGCCGCTGGAAGCCGCCGAACGCGACTGCTGGCCTGTCATGCTCAGGGC
CGCCGCGCTGCGCTTCTGGGTATCCCGGCTGCAAGATCTCTATCAGCCCGCGAGCGGCGAACTCACCTACACCAAGGATC
CGGCCGTGTTCCAGAACCTGCTGCTGGGCCACCGCCTCCGGCAGGACTTCTGGCTGGACTAA

Upstream 100 bases:

>100_bases
CTGATAGACGACAACGGCTCCGGCAACATGAGGCAGATCGACCCTGCGACCCGCATCGTGATCCCCCGCTGGGTCCTGGT
TCGATTCTGACGGAGGCGGC

Downstream 100 bases:

>100_bases
CACTGTCCGAAGGCCGTATTGCGCGAGTCGAGCCAGGAATTCACGATAACGTCATCTGGCTGATCTTGAAAAATGCGTGA
GTTGGGATATCATGCAGGAT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSVYTTVSRESLQHWLQGYALGQLLELKGIAAGITNTNYFVTTTHGRYVLTLFETLHLDELPYYLTLMSHLAKHGVACPA
PVADHTDRFASTLAGKPACLVSCLGGQDVSHPSAEQCRAVGETLAQMHKAGATFPLQMKNPRGPRWWSRTAQQLYPQLPA
DQAELLREEIQFQDSHRFDHLPSGVIHADLFRDNVLLNGNHISGFIDFYYACNDILLYDVAIAVNDWARLDDGELDGGLA
KAFLEGYQSERPLEAAERDCWPVMLRAAALRFWVSRLQDLYQPASGELTYTKDPAVFQNLLLGHRLRQDFWLD

Sequences:

>Translated_313_residues
MSVYTTVSRESLQHWLQGYALGQLLELKGIAAGITNTNYFVTTTHGRYVLTLFETLHLDELPYYLTLMSHLAKHGVACPA
PVADHTDRFASTLAGKPACLVSCLGGQDVSHPSAEQCRAVGETLAQMHKAGATFPLQMKNPRGPRWWSRTAQQLYPQLPA
DQAELLREEIQFQDSHRFDHLPSGVIHADLFRDNVLLNGNHISGFIDFYYACNDILLYDVAIAVNDWARLDDGELDGGLA
KAFLEGYQSERPLEAAERDCWPVMLRAAALRFWVSRLQDLYQPASGELTYTKDPAVFQNLLLGHRLRQDFWLD
>Mature_312_residues
SVYTTVSRESLQHWLQGYALGQLLELKGIAAGITNTNYFVTTTHGRYVLTLFETLHLDELPYYLTLMSHLAKHGVACPAP
VADHTDRFASTLAGKPACLVSCLGGQDVSHPSAEQCRAVGETLAQMHKAGATFPLQMKNPRGPRWWSRTAQQLYPQLPAD
QAELLREEIQFQDSHRFDHLPSGVIHADLFRDNVLLNGNHISGFIDFYYACNDILLYDVAIAVNDWARLDDGELDGGLAK
AFLEGYQSERPLEAAERDCWPVMLRAAALRFWVSRLQDLYQPASGELTYTKDPAVFQNLLLGHRLRQDFWLD

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 35234; Mature: 35103

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYTTVSRESLQHWLQGYALGQLLELKGIAAGITNTNYFVTTTHGRYVLTLFETLHLDE
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHC
LPYYLTLMSHLAKHGVACPAPVADHTDRFASTLAGKPACLVSCLGGQDVSHPSAEQCRAV
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHEECCCCCCCCCCHHHHHHH
GETLAQMHKAGATFPLQMKNPRGPRWWSRTAQQLYPQLPADQAELLREEIQFQDSHRFDH
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
LPSGVIHADLFRDNVLLNGNHISGFIDFYYACNDILLYDVAIAVNDWARLDDGELDGGLA
CCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KAFLEGYQSERPLEAAERDCWPVMLRAAALRFWVSRLQDLYQPASGELTYTKDPAVFQNL
HHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
LLGHRLRQDFWLD
HHHHHHHHHHCCC
>Mature Secondary Structure 
SVYTTVSRESLQHWLQGYALGQLLELKGIAAGITNTNYFVTTTHGRYVLTLFETLHLDE
CEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHC
LPYYLTLMSHLAKHGVACPAPVADHTDRFASTLAGKPACLVSCLGGQDVSHPSAEQCRAV
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHEECCCCCCCCCCHHHHHHH
GETLAQMHKAGATFPLQMKNPRGPRWWSRTAQQLYPQLPADQAELLREEIQFQDSHRFDH
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
LPSGVIHADLFRDNVLLNGNHISGFIDFYYACNDILLYDVAIAVNDWARLDDGELDGGLA
CCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KAFLEGYQSERPLEAAERDCWPVMLRAAALRFWVSRLQDLYQPASGELTYTKDPAVFQNL
HHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
LLGHRLRQDFWLD
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA