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The map label for this gene is nuoA1 [H]

Identifier: 34496088

GI number: 34496088

Start: 664864

End: 665223

Strand: Reverse

Name: nuoA1 [H]

Synonym: CV_0633

Alternate gene names: 34496088

Gene position: 665223-664864 (Counterclockwise)

Preceding gene: 34496090

Following gene: 34496087

Centisome position: 14.0

GC content: 60.56

Gene sequence:

>360_bases
ATGCTGGAGAATTACTTCCCCATCCTGCTATTCATCGTGGTGGGACTCTTGGTGGGCGTGCTGCCCATGATGCTGGGCCG
ATTCCTCGGCCCCAACCGTCCTGACCCGGAAAAGCTGTCGCCGTACGAGTGCGGCTTCGAGGCGTTCGAGGACGCGCGGA
TGCGCTTCGACGTACGCTACTACCTGGTGGCCATCCTGTTCATCCTGTTCGACCTGGAAGTGGCATTCATGATCCCGTGG
GCGGTGACGCTCAGGGACGAGTTGGGCCTGTTCGGCCTGGGGGCGATGGCGGTATTCCTCGGCATCCTCACCATAGGCTT
CGTCTATGAGTGGAAAAAGGGCGCGCTGCAGTGGGATTGA

Upstream 100 bases:

>100_bases
TTCCGGCCACCCCGTTTACGAAGTTTTACTTTCCCGCAGGCAACTTGCCGGACCGGAACAGTCTCTTTCCCTTTGCCGAT
AGGACAGGAAACAGACCGAC

Downstream 100 bases:

>100_bases
GCCACCCTGGGGTTGGCAGGCCGAAACGAAGCCTGAATGCAGGCTTGGCAACACGCACGCTGCAATATCATGACGCGCGC
CCTTTTCCATCCAGCCGGCT

Product: NADH dehydrogenase I chain A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MLENYFPILLFIVVGLLVGVLPMMLGRFLGPNRPDPEKLSPYECGFEAFEDARMRFDVRYYLVAILFILFDLEVAFMIPW
AVTLRDELGLFGLGAMAVFLGILTIGFVYEWKKGALQWD

Sequences:

>Translated_119_residues
MLENYFPILLFIVVGLLVGVLPMMLGRFLGPNRPDPEKLSPYECGFEAFEDARMRFDVRYYLVAILFILFDLEVAFMIPW
AVTLRDELGLFGLGAMAVFLGILTIGFVYEWKKGALQWD
>Mature_119_residues
MLENYFPILLFIVVGLLVGVLPMMLGRFLGPNRPDPEKLSPYECGFEAFEDARMRFDVRYYLVAILFILFDLEVAFMIPW
AVTLRDELGLFGLGAMAVFLGILTIGFVYEWKKGALQWD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=119, Percent_Identity=31.0924369747899, Blast_Score=72, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13663; Mature: 13663

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENYFPILLFIVVGLLVGVLPMMLGRFLGPNRPDPEKLSPYECGFEAFEDARMRFDVRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
YLVAILFILFDLEVAFMIPWAVTLRDELGLFGLGAMAVFLGILTIGFVYEWKKGALQWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLENYFPILLFIVVGLLVGVLPMMLGRFLGPNRPDPEKLSPYECGFEAFEDARMRFDVRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
YLVAILFILFDLEVAFMIPWAVTLRDELGLFGLGAMAVFLGILTIGFVYEWKKGALQWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]