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The map label for this gene is yegE [H]

Identifier: 34495986

GI number: 34495986

Start: 565319

End: 566521

Strand: Reverse

Name: yegE [H]

Synonym: CV_0531

Alternate gene names: 34495986

Gene position: 566521-565319 (Counterclockwise)

Preceding gene: 34495992

Following gene: 34495978

Centisome position: 11.92

GC content: 64.09

Gene sequence:

>1203_bases
ATGTTCGATAGCAGCGACAAAGGCATCATGCTGAAGGCCATCATGGTCGCCGCGCCCATCCTGCTGTGCATGGGCCTGCT
GCCGGTGCTGTCCTTCTACATCGAGAAAATGGAAGAGAACGGCCGCGCCCAGATCGTCGAATACATCGCCATCGCCCAGG
CCGCGATGGAAGTGAAATTCGACGCCGCGGACCTGAACGGCTGGCAGACCGGCTACGCCTTCGACATCGTCCGCAACATC
GAGGGGGCCAGCCACGACGACGCCATCTCCCGATCGGAATTCCTGCGTTCGGCCGACAACTTCCGCCGCGATATCCAGAC
CCTGCGCGGAATGGCGCTCAGCGCCGACCAGCGCAGCCAGCTGGACAGCGTGCAGCGGGATTTCAACGCCTTCATGGAGC
GGGACCGCGACATCATCGCCATGTACCGCTCCGGCGACGCCGCCCAGCGCGACAAGGCATCCAAGCTGGTGATGGGCGAG
GAAATCCAGATCTTCACCCACATCTCGCAGAACACCAACGCGCTGGCGGTGTCCATCACGCTGGACCTGATGAAGAAAGT
GGCCCAATCCAATTCCTACGGCATCGTCGCCCGCTGGATCATGCTGGTGATGTGGATCATCGCCAGCGCGATGGCCATCC
TGCTGGTGCGGCTGCTGCACAAATGGCTGGGGCAAATGCGCAGCCTGATGCAAAAGCTGGAAGCCCTGGCAGGCACCGAC
GAGCTGACCCAGCTGCCCAACCGCCGCACCTGGGACATCCAGATAGAAATGATGCTGGCCACCGCGCGCCGCTACCGCCA
GCCCATCGCGGTGGCGCTGTTCGATCTGGACCATTTCAAGCAATTCAACGACAGCTACGGCCACCCCGAAGGCGACCGGC
TGCTGCGCGAGGTGGCGGTGCTGATCAAGTCGCGGATGCGGCAATCGGACCTGTTCGCCCGCTTCGGCGGCGAGGAGTTC
GTGCTGGCGCTGATGGACTGCAATCTGGACCAGGCCGCCGCCCGCATCGAATCGCTGCGCGGCAATCTGCCGGATCAGCA
GACCTTTTCCGTCGGCGTCACCGTGTGGCTGGAGGGCGAGCGGATACACAGCACGCTGGCGCGGGCGGACAAGGCGCTGT
ATCTGGCCAAGAACGGCGGACGGGATAGGGTGGTGAGCGTGGAGCCGCCGGCGCCGGGACGGCGACCAGAGGCGGCGGAT
TAG

Upstream 100 bases:

>100_bases
CTCGCGACAACTAAGTATTTGTTCGTACAAAAACCATCTATGTTGAAGCACGGCCGCCCGCACACGCCGCGGCCGCTCCC
TTTCCCCAGGCGGAGCGACC

Downstream 100 bases:

>100_bases
CGCCGGCCAACCATTTATTGTGCAGTTTGCTGCGCGATGCTGCATAAAAAACGCCTTGCCGGGGCACCCGCAGCAAGGCG
ATTTCACCGGGTTCAACCCA

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFDSSDKGIMLKAIMVAAPILLCMGLLPVLSFYIEKMEENGRAQIVEYIAIAQAAMEVKFDAADLNGWQTGYAFDIVRNI
EGASHDDAISRSEFLRSADNFRRDIQTLRGMALSADQRSQLDSVQRDFNAFMERDRDIIAMYRSGDAAQRDKASKLVMGE
EIQIFTHISQNTNALAVSITLDLMKKVAQSNSYGIVARWIMLVMWIIASAMAILLVRLLHKWLGQMRSLMQKLEALAGTD
ELTQLPNRRTWDIQIEMMLATARRYRQPIAVALFDLDHFKQFNDSYGHPEGDRLLREVAVLIKSRMRQSDLFARFGGEEF
VLALMDCNLDQAAARIESLRGNLPDQQTFSVGVTVWLEGERIHSTLARADKALYLAKNGGRDRVVSVEPPAPGRRPEAAD

Sequences:

>Translated_400_residues
MFDSSDKGIMLKAIMVAAPILLCMGLLPVLSFYIEKMEENGRAQIVEYIAIAQAAMEVKFDAADLNGWQTGYAFDIVRNI
EGASHDDAISRSEFLRSADNFRRDIQTLRGMALSADQRSQLDSVQRDFNAFMERDRDIIAMYRSGDAAQRDKASKLVMGE
EIQIFTHISQNTNALAVSITLDLMKKVAQSNSYGIVARWIMLVMWIIASAMAILLVRLLHKWLGQMRSLMQKLEALAGTD
ELTQLPNRRTWDIQIEMMLATARRYRQPIAVALFDLDHFKQFNDSYGHPEGDRLLREVAVLIKSRMRQSDLFARFGGEEF
VLALMDCNLDQAAARIESLRGNLPDQQTFSVGVTVWLEGERIHSTLARADKALYLAKNGGRDRVVSVEPPAPGRRPEAAD
>Mature_400_residues
MFDSSDKGIMLKAIMVAAPILLCMGLLPVLSFYIEKMEENGRAQIVEYIAIAQAAMEVKFDAADLNGWQTGYAFDIVRNI
EGASHDDAISRSEFLRSADNFRRDIQTLRGMALSADQRSQLDSVQRDFNAFMERDRDIIAMYRSGDAAQRDKASKLVMGE
EIQIFTHISQNTNALAVSITLDLMKKVAQSNSYGIVARWIMLVMWIIASAMAILLVRLLHKWLGQMRSLMQKLEALAGTD
ELTQLPNRRTWDIQIEMMLATARRYRQPIAVALFDLDHFKQFNDSYGHPEGDRLLREVAVLIKSRMRQSDLFARFGGEEF
VLALMDCNLDQAAARIESLRGNLPDQQTFSVGVTVWLEGERIHSTLARADKALYLAKNGGRDRVVSVEPPAPGRRPEAAD

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=174, Percent_Identity=38.5057471264368, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787262, Length=225, Percent_Identity=31.5555555555556, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082007, Length=202, Percent_Identity=31.6831683168317, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081881, Length=185, Percent_Identity=38.3783783783784, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=31.4465408805031, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081974, Length=264, Percent_Identity=24.6212121212121, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787541, Length=178, Percent_Identity=33.7078651685393, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788085, Length=170, Percent_Identity=32.9411764705882, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=31.9018404907975, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=176, Percent_Identity=30.6818181818182, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=29.4797687861272, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 45081; Mature: 45081

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSSDKGIMLKAIMVAAPILLCMGLLPVLSFYIEKMEENGRAQIVEYIAIAQAAMEVKF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
DAADLNGWQTGYAFDIVRNIEGASHDDAISRSEFLRSADNFRRDIQTLRGMALSADQRSQ
ECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LDSVQRDFNAFMERDRDIIAMYRSGDAAQRDKASKLVMGEEIQIFTHISQNTNALAVSIT
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEH
LDLMKKVAQSNSYGIVARWIMLVMWIIASAMAILLVRLLHKWLGQMRSLMQKLEALAGTD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ELTQLPNRRTWDIQIEMMLATARRYRQPIAVALFDLDHFKQFNDSYGHPEGDRLLREVAV
HHHHCCCCCEEEEEEHHHHHHHHHHHCCHHHEECCHHHHHHHCCCCCCCCHHHHHHHHHH
LIKSRMRQSDLFARFGGEEFVLALMDCNLDQAAARIESLRGNLPDQQTFSVGVTVWLEGE
HHHHHHHHHHHHHHCCCHHHEEEEHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCH
RIHSTLARADKALYLAKNGGRDRVVSVEPPAPGRRPEAAD
HHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MFDSSDKGIMLKAIMVAAPILLCMGLLPVLSFYIEKMEENGRAQIVEYIAIAQAAMEVKF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
DAADLNGWQTGYAFDIVRNIEGASHDDAISRSEFLRSADNFRRDIQTLRGMALSADQRSQ
ECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LDSVQRDFNAFMERDRDIIAMYRSGDAAQRDKASKLVMGEEIQIFTHISQNTNALAVSIT
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEH
LDLMKKVAQSNSYGIVARWIMLVMWIIASAMAILLVRLLHKWLGQMRSLMQKLEALAGTD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ELTQLPNRRTWDIQIEMMLATARRYRQPIAVALFDLDHFKQFNDSYGHPEGDRLLREVAV
HHHHCCCCCEEEEEEHHHHHHHHHHHCCHHHEECCHHHHHHHCCCCCCCCHHHHHHHHHH
LIKSRMRQSDLFARFGGEEFVLALMDCNLDQAAARIESLRGNLPDQQTFSVGVTVWLEGE
HHHHHHHHHHHHHHCCCHHHEEEEHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCH
RIHSTLARADKALYLAKNGGRDRVVSVEPPAPGRRPEAAD
HHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]