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The map label for this gene is aroE [H]

Identifier: 33864521

GI number: 33864521

Start: 2390498

End: 2391409

Strand: Direct

Name: aroE [H]

Synonym: PMT2257

Alternate gene names: 33864521

Gene position: 2390498-2391409 (Clockwise)

Preceding gene: 33864520

Following gene: 33864522

Centisome position: 99.15

GC content: 53.51

Gene sequence:

>912_bases
ATGATTAGCGGCACAACCTCCCTAATAGGCCTGCTCGGCCAACCAGTGCACCATTCCCTCTCACCGGTGATGCAAAACGC
AGCCCTCGCTGCAATGAATCTCGACTGGTGCTACATGGCCATGCCATGCGAAACCAACGATCTGGCCAATGTGCTCTGCG
CTCTGCGTTCGATCAACTGCCTTGGACTGAACATCACCATCCCCCACAAACAAGACGTGGCCAAAACCTGTCGAGAGCTC
AGCCCATTAGCAAAACGACTGAAAGCCGTCAACACTCTGATCCCTCATGCCGACGGCGGCTGGACAGGCACCAACACAGA
CGTGGCCGGTTTTATTGCACCCCTTCAAGAAAGCAAGTGCGAGTGGCATGGGCGTCGTGCAGTCGTGCTCGGTTGCGGTG
GTAGCGCCCGAGCAGTCGTTGCAGGTCTGCAAGATTTAAAATTGGCTCAAATCATGGTGGTTGGCCGCCGATCTGATGCG
CTGAAGAGATTTCTCGATGATCTCCAGCCCAACCCAGCCAGCTCCGAATCTGATTGCCAAGTGCTCTTGCAAGGGATTCT
CCAACATGACCCTGCTCTGATTGAACAGCTAACCAAAGCCGATCTGGTGGTCAACACCACACCAATAGGCATGTCCCAAA
ACCGTGCGGAAACATCAACTCCTAGAGCGCCAATGCCCCTGGGGAAGAAGATTTGGCAAAACTTAAGCCCAAAGACAACT
CTCTATGACCTGATTTACACACCAAAACCAACCGCCTGGCTAACCTTAGGAACTGAACATGGCTGCCATTGCATAGATGG
CCTCGAAATGCTTGTTCAACAAGGCGCTGCCTCTCTAAGGCTCTGGAGCGGCAACAACAAGGTGCCTGTCGAAGAGATGA
GAAAAGCTGCTCTGAGCTGGCTCACGGTTTAG

Upstream 100 bases:

>100_bases
GAACAGGTGCATCCTCGGCAGTGAGACCACTTAGAGGCGAGGTGTGGTTCCCGAACAGCTCGCCCGGCAGGCTGGGCATA
GAACCGATCAAGCAATGGGA

Downstream 100 bases:

>100_bases
CGTCATAGCAGTGATCTGACCCCCATGCTGATCCCTATCTGGCAACGGTTGCTGGGAGTGCTGATTTACATGCTCCCTTG
GAGCGACACCATTCCATTTG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MISGTTSLIGLLGQPVHHSLSPVMQNAALAAMNLDWCYMAMPCETNDLANVLCALRSINCLGLNITIPHKQDVAKTCREL
SPLAKRLKAVNTLIPHADGGWTGTNTDVAGFIAPLQESKCEWHGRRAVVLGCGGSARAVVAGLQDLKLAQIMVVGRRSDA
LKRFLDDLQPNPASSESDCQVLLQGILQHDPALIEQLTKADLVVNTTPIGMSQNRAETSTPRAPMPLGKKIWQNLSPKTT
LYDLIYTPKPTAWLTLGTEHGCHCIDGLEMLVQQGAASLRLWSGNNKVPVEEMRKAALSWLTV

Sequences:

>Translated_303_residues
MISGTTSLIGLLGQPVHHSLSPVMQNAALAAMNLDWCYMAMPCETNDLANVLCALRSINCLGLNITIPHKQDVAKTCREL
SPLAKRLKAVNTLIPHADGGWTGTNTDVAGFIAPLQESKCEWHGRRAVVLGCGGSARAVVAGLQDLKLAQIMVVGRRSDA
LKRFLDDLQPNPASSESDCQVLLQGILQHDPALIEQLTKADLVVNTTPIGMSQNRAETSTPRAPMPLGKKIWQNLSPKTT
LYDLIYTPKPTAWLTLGTEHGCHCIDGLEMLVQQGAASLRLWSGNNKVPVEEMRKAALSWLTV
>Mature_303_residues
MISGTTSLIGLLGQPVHHSLSPVMQNAALAAMNLDWCYMAMPCETNDLANVLCALRSINCLGLNITIPHKQDVAKTCREL
SPLAKRLKAVNTLIPHADGGWTGTNTDVAGFIAPLQESKCEWHGRRAVVLGCGGSARAVVAGLQDLKLAQIMVVGRRSDA
LKRFLDDLQPNPASSESDCQVLLQGILQHDPALIEQLTKADLVVNTTPIGMSQNRAETSTPRAPMPLGKKIWQNLSPKTT
LYDLIYTPKPTAWLTLGTEHGCHCIDGLEMLVQQGAASLRLWSGNNKVPVEEMRKAALSWLTV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=294, Percent_Identity=30.952380952381, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789675, Length=275, Percent_Identity=28.3636363636364, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=277, Percent_Identity=27.0758122743682, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 32784; Mature: 32784

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGTTSLIGLLGQPVHHSLSPVMQNAALAAMNLDWCYMAMPCETNDLANVLCALRSINC
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHHCCCE
LGLNITIPHKQDVAKTCRELSPLAKRLKAVNTLIPHADGGWTGTNTDVAGFIAPLQESKC
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCH
EWHGRRAVVLGCGGSARAVVAGLQDLKLAQIMVVGRRSDALKRFLDDLQPNPASSESDCQ
HHCCCEEEEEECCCCHHHHHHHHHHHHEEHHEEECCCHHHHHHHHHHCCCCCCCCCHHHH
VLLQGILQHDPALIEQLTKADLVVNTTPIGMSQNRAETSTPRAPMPLGKKIWQNLSPKTT
HHHHHHHHCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCE
LYDLIYTPKPTAWLTLGTEHGCHCIDGLEMLVQQGAASLRLWSGNNKVPVEEMRKAALSW
EEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
LTV
HCC
>Mature Secondary Structure
MISGTTSLIGLLGQPVHHSLSPVMQNAALAAMNLDWCYMAMPCETNDLANVLCALRSINC
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHHCCCE
LGLNITIPHKQDVAKTCRELSPLAKRLKAVNTLIPHADGGWTGTNTDVAGFIAPLQESKC
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCH
EWHGRRAVVLGCGGSARAVVAGLQDLKLAQIMVVGRRSDALKRFLDDLQPNPASSESDCQ
HHCCCEEEEEECCCCHHHHHHHHHHHHEEHHEEECCCHHHHHHHHHHCCCCCCCCCHHHH
VLLQGILQHDPALIEQLTKADLVVNTTPIGMSQNRAETSTPRAPMPLGKKIWQNLSPKTT
HHHHHHHHCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCE
LYDLIYTPKPTAWLTLGTEHGCHCIDGLEMLVQQGAASLRLWSGNNKVPVEEMRKAALSW
EEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
LTV
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA