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The map label for this gene is ynaI [H]

Identifier: 33864341

GI number: 33864341

Start: 2187636

End: 2188757

Strand: Direct

Name: ynaI [H]

Synonym: PMT2077

Alternate gene names: 33864341

Gene position: 2187636-2188757 (Clockwise)

Preceding gene: 33864339

Following gene: 33864342

Centisome position: 90.74

GC content: 47.24

Gene sequence:

>1122_bases
ATGCCCGATACGCAACAAGAGCTGCTCAACAAGATCGATTTTTTTCAGAGTCAAGAAGGGATCCTGGTCGGAACTGTCTT
CTTAGCTGTTCTTTGGTTGATACTCGTTCTTCTGGATAAGTACGGCAGGCGAATTGGCCCTCTGGTAGCGAGATCCATCC
GAAGGCCCTTATTGCTTGGATTTAGTTCAGCTCTTTACTTGGGTTGGCTGTTACACCTCTTGGAACTGCAAGCCAAGGCC
TTGTTGCCTATTAAAAGTTCAGCAGTCTCAACTGCTCTGGTGGTGATCGCTCTGGGCTGGGCCACGATCAATCTCGGCCG
GGCACTGCTCCTGCAATCGAATCGCATTCAACGCTGGCTGAAGGTAGAAGATCCCAGAGATGAGGCGATGTTGACCGCCT
TATTGGATCGAGTTTTCACCATTGGAGTCATTGTTTTAACTATCGCGGCCCTGATGGTGACTTTTGGAGTGTCTACCGCA
GCAGTAGGCGCTTTGCTTGGTGGAGCAGGCATTGGCCTCGGCTTTGGGACACAGCAAATTTCTCAGAATTTCCTTGCAGG
GTTCATGCTCTTTTTTACTCGTCCATTCTCAGAAGGTGACTGGATTAGCGTCTCGAGCTTTGATGATGGAACAGTTGAGA
AAATTGGCTGGTATCACACCCGCATTCGCACCTTTGATCGTCGACCACTCTATATCCCAAATTCGATCTTTGCGACTACT
CCGATCGAGAATCCTGGACGAATGTATAACAGAAGAATCAAGGCCAGCATTAGTCTTCGCTACGAAGATCTGCCCCGTAT
CGACGCGATTAGCAAGAATGTTCGTAGTCTGCTATTAAACCATCCAGAGATAGATCAAAAACAGAGCATCTTAGTGAATT
TCAACGAATGGGATAGCTCCTCGATCAACATGATGGTGTATTGCTTTACTAAAACAACTGTTTGGAAAGACTGGCTAGAT
ATTCAACAGGAGGTCTTCCTCCAGATTGCAGACATTGTTCAGAAAGCTGGTGGTGATTTTGCCTTCAATTGCACCACCCT
CTATCCGGCGCCAAACCTGAACGATGACAATCCAATTAGTCGCTTGGGTGAAGATCTAAAATCGAACAGATCGCTGCAGT
AA

Upstream 100 bases:

>100_bases
CTTGCTCTTGATCAATTGTGGCTGCTGTGATAAAGGCAGTTTTATCTCTACCCTGATTCAACTTTCCTCAGTAAGATTTG
CTCAAACCAGATCAAGCCGC

Downstream 100 bases:

>100_bases
ACAAAGCTCAAATCTATCATTTATAAATATGAGTCAAACGTTTCCAGGTAATTGATGTGCGACTGGAAAAAAGCCGAACC
ATCAGATTTCATTTGCGAAG

Product: small mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPDTQQELLNKIDFFQSQEGILVGTVFLAVLWLILVLLDKYGRRIGPLVARSIRRPLLLGFSSALYLGWLLHLLELQAKA
LLPIKSSAVSTALVVIALGWATINLGRALLLQSNRIQRWLKVEDPRDEAMLTALLDRVFTIGVIVLTIAALMVTFGVSTA
AVGALLGGAGIGLGFGTQQISQNFLAGFMLFFTRPFSEGDWISVSSFDDGTVEKIGWYHTRIRTFDRRPLYIPNSIFATT
PIENPGRMYNRRIKASISLRYEDLPRIDAISKNVRSLLLNHPEIDQKQSILVNFNEWDSSSINMMVYCFTKTTVWKDWLD
IQQEVFLQIADIVQKAGGDFAFNCTTLYPAPNLNDDNPISRLGEDLKSNRSLQ

Sequences:

>Translated_373_residues
MPDTQQELLNKIDFFQSQEGILVGTVFLAVLWLILVLLDKYGRRIGPLVARSIRRPLLLGFSSALYLGWLLHLLELQAKA
LLPIKSSAVSTALVVIALGWATINLGRALLLQSNRIQRWLKVEDPRDEAMLTALLDRVFTIGVIVLTIAALMVTFGVSTA
AVGALLGGAGIGLGFGTQQISQNFLAGFMLFFTRPFSEGDWISVSSFDDGTVEKIGWYHTRIRTFDRRPLYIPNSIFATT
PIENPGRMYNRRIKASISLRYEDLPRIDAISKNVRSLLLNHPEIDQKQSILVNFNEWDSSSINMMVYCFTKTTVWKDWLD
IQQEVFLQIADIVQKAGGDFAFNCTTLYPAPNLNDDNPISRLGEDLKSNRSLQ
>Mature_372_residues
PDTQQELLNKIDFFQSQEGILVGTVFLAVLWLILVLLDKYGRRIGPLVARSIRRPLLLGFSSALYLGWLLHLLELQAKAL
LPIKSSAVSTALVVIALGWATINLGRALLLQSNRIQRWLKVEDPRDEAMLTALLDRVFTIGVIVLTIAALMVTFGVSTAA
VGALLGGAGIGLGFGTQQISQNFLAGFMLFFTRPFSEGDWISVSSFDDGTVEKIGWYHTRIRTFDRRPLYIPNSIFATTP
IENPGRMYNRRIKASISLRYEDLPRIDAISKNVRSLLLNHPEIDQKQSILVNFNEWDSSSINMMVYCFTKTTVWKDWLDI
QQEVFLQIADIVQKAGGDFAFNCTTLYPAPNLNDDNPISRLGEDLKSNRSLQ

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=216, Percent_Identity=50, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789291, Length=288, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786670, Length=106, Percent_Identity=37.7358490566038, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI2367355, Length=105, Percent_Identity=32.3809523809524, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 41855; Mature: 41724

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00216 SUGAR_TRANSPORT_1 ; PS01246 UPF0003

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTQQELLNKIDFFQSQEGILVGTVFLAVLWLILVLLDKYGRRIGPLVARSIRRPLLLG
CCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHH
FSSALYLGWLLHLLELQAKALLPIKSSAVSTALVVIALGWATINLGRALLLQSNRIQRWL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVEDPRDEAMLTALLDRVFTIGVIVLTIAALMVTFGVSTAAVGALLGGAGIGLGFGTQQI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHH
SQNFLAGFMLFFTRPFSEGDWISVSSFDDGTVEKIGWYHTRIRTFDRRPLYIPNSIFATT
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEC
PIENPGRMYNRRIKASISLRYEDLPRIDAISKNVRSLLLNHPEIDQKQSILVNFNEWDSS
CCCCCHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
SINMMVYCFTKTTVWKDWLDIQQEVFLQIADIVQKAGGDFAFNCTTLYPAPNLNDDNPIS
CCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHH
RLGEDLKSNRSLQ
HHHHHHHCCCCCC
>Mature Secondary Structure 
PDTQQELLNKIDFFQSQEGILVGTVFLAVLWLILVLLDKYGRRIGPLVARSIRRPLLLG
CCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHH
FSSALYLGWLLHLLELQAKALLPIKSSAVSTALVVIALGWATINLGRALLLQSNRIQRWL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVEDPRDEAMLTALLDRVFTIGVIVLTIAALMVTFGVSTAAVGALLGGAGIGLGFGTQQI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHH
SQNFLAGFMLFFTRPFSEGDWISVSSFDDGTVEKIGWYHTRIRTFDRRPLYIPNSIFATT
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEC
PIENPGRMYNRRIKASISLRYEDLPRIDAISKNVRSLLLNHPEIDQKQSILVNFNEWDSS
CCCCCHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
SINMMVYCFTKTTVWKDWLDIQQEVFLQIADIVQKAGGDFAFNCTTLYPAPNLNDDNPIS
CCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHH
RLGEDLKSNRSLQ
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]