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The map label for this gene is fabG [C]

Identifier: 33864299

GI number: 33864299

Start: 2146571

End: 2147317

Strand: Direct

Name: fabG [C]

Synonym: PMT2034

Alternate gene names: 33864299

Gene position: 2146571-2147317 (Clockwise)

Preceding gene: 33864298

Following gene: 33864300

Centisome position: 89.04

GC content: 54.22

Gene sequence:

>747_bases
ATGGGTCAAGCAGCGAGAACTCCGATTCGCAGCTCCTTTGTGCTCGGAAGTACCAGTGAAATAGCCAAGGCAATTTGCCA
TGAGTTGGCTCGATGTGGCTGTCGTCAGTTCCATTTGATTGCCCGCAACCAGGCTGGGAACGAACAACTGGCCGAACAAC
TGAGAAATCACTATGGCGCAGTCGTCACCCAGGAGCAGACCGATCTTTTGACTGATGTAGCCCTTGATGGTCCTGGCAAG
CCGCAGGTGGGCAACTATGACTTGTATTTGATCACTGCGGGTTCTCTTGGTGATCTCGAACTAGCGCGCAACGATGCCAC
TGAGGCCTTGCGAATCACAGCTGCAAACTACAGCGGTCTACTGCCATGGTTAACTGCAATTGCTACTCCTGAGCGGCTTT
CTGGCCCGGGGCGGTTGTGGGTGTTCAGTTCAGTTGCAGCTGATCTTGGCAGACCCTCCAACTATCACTACGGAGCAGCC
AAAGCTGCTCTTACTGCGTTCTGCGAGGGTCTACAACTGCGCTGCCAAAGGAAGCCTTTTGCAGTGCGCACCATCAAGGC
TGGCTTTATGGCCACATCGATGACGATTGGCAAGGCACCAAAAGTTCTGTGCGTCAGTCCACAATCGGTGGCGCGTGATC
TACTGAGACGCCCCAACCGTAGAGGTATCGAATACCTCCCCTGGTGGTGGGCACAGATCATGTGGTTCATTCGCTTGTTG
CCTGCGCCCTTTGCTTCAAGGCTGTGA

Upstream 100 bases:

>100_bases
TTATCACCCTTTGGTCAATCGTGGCTCTCGCTGCTGCGATTAGGATTTTCTGGCCTTATCCAGCCTTCTCATCTAGCAAG
TTTGCGAAAGGATGAACACT

Downstream 100 bases:

>100_bases
CCTTGCCCCTCTCTTCGCAAACACAAATCCTCAGCGGTTGGGGCCGCACAATGCCAGTGCAGGCAAAGGTTGTGCAGCCA
GCCAGCGTCCAACAAGTCCA

Product: hypothetical protein

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MGQAARTPIRSSFVLGSTSEIAKAICHELARCGCRQFHLIARNQAGNEQLAEQLRNHYGAVVTQEQTDLLTDVALDGPGK
PQVGNYDLYLITAGSLGDLELARNDATEALRITAANYSGLLPWLTAIATPERLSGPGRLWVFSSVAADLGRPSNYHYGAA
KAALTAFCEGLQLRCQRKPFAVRTIKAGFMATSMTIGKAPKVLCVSPQSVARDLLRRPNRRGIEYLPWWWAQIMWFIRLL
PAPFASRL

Sequences:

>Translated_248_residues
MGQAARTPIRSSFVLGSTSEIAKAICHELARCGCRQFHLIARNQAGNEQLAEQLRNHYGAVVTQEQTDLLTDVALDGPGK
PQVGNYDLYLITAGSLGDLELARNDATEALRITAANYSGLLPWLTAIATPERLSGPGRLWVFSSVAADLGRPSNYHYGAA
KAALTAFCEGLQLRCQRKPFAVRTIKAGFMATSMTIGKAPKVLCVSPQSVARDLLRRPNRRGIEYLPWWWAQIMWFIRLL
PAPFASRL
>Mature_247_residues
GQAARTPIRSSFVLGSTSEIAKAICHELARCGCRQFHLIARNQAGNEQLAEQLRNHYGAVVTQEQTDLLTDVALDGPGKP
QVGNYDLYLITAGSLGDLELARNDATEALRITAANYSGLLPWLTAIATPERLSGPGRLWVFSSVAADLGRPSNYHYGAAK
AALTAFCEGLQLRCQRKPFAVRTIKAGFMATSMTIGKAPKVLCVSPQSVARDLLRRPNRRGIEYLPWWWAQIMWFIRLLP
APFASRL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 27254; Mature: 27123

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQAARTPIRSSFVLGSTSEIAKAICHELARCGCRQFHLIARNQAGNEQLAEQLRNHYGA
CCCCCCCCCHHHEECCCHHHHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHCCC
VVTQEQTDLLTDVALDGPGKPQVGNYDLYLITAGSLGDLELARNDATEALRITAANYSGL
EEECCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCH
LPWLTAIATPERLSGPGRLWVFSSVAADLGRPSNYHYGAAKAALTAFCEGLQLRCQRKPF
HHHHHHHCCHHHCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AVRTIKAGFMATSMTIGKAPKVLCVSPQSVARDLLRRPNRRGIEYLPWWWAQIMWFIRLL
EEEHHHHHHHHHHEECCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
PAPFASRL
CCHHHCCC
>Mature Secondary Structure 
GQAARTPIRSSFVLGSTSEIAKAICHELARCGCRQFHLIARNQAGNEQLAEQLRNHYGA
CCCCCCCCHHHEECCCHHHHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHCCC
VVTQEQTDLLTDVALDGPGKPQVGNYDLYLITAGSLGDLELARNDATEALRITAANYSGL
EEECCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCH
LPWLTAIATPERLSGPGRLWVFSSVAADLGRPSNYHYGAAKAALTAFCEGLQLRCQRKPF
HHHHHHHCCHHHCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AVRTIKAGFMATSMTIGKAPKVLCVSPQSVARDLLRRPNRRGIEYLPWWWAQIMWFIRLL
EEEHHHHHHHHHHEECCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
PAPFASRL
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]