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The map label for this gene is cysC [H]

Identifier: 33864294

GI number: 33864294

Start: 2140944

End: 2141627

Strand: Direct

Name: cysC [H]

Synonym: PMT2029

Alternate gene names: 33864294

Gene position: 2140944-2141627 (Clockwise)

Preceding gene: 33864293

Following gene: 33864296

Centisome position: 88.8

GC content: 53.36

Gene sequence:

>684_bases
ATGGAGAATGGCAGCCCAATCAACATCAAGACCATGAGCTCTGCCCCGCAAGGAGACACAAACCCCAAGGGCACGAACAT
TGTCTGGCATGAAGCCTCCGTAGACCGTCAATCGCGAGCACAACAACGCGGCCACCGCAGTGCAATCCTCTGGTTCACTG
GCCTATCCGGTTCTGGCAAAAGCACCCTTGCCAATGCAGTGAATGCGGCACTTTTTGAGCAAGGTCTTGCCACCTATGTC
TTAGATGGCGACAACATTCGCCATAGCCTTTGCAAAGACCTCGGCTTCTCCGACTCAGATCGAGAGGAGAACATTCGCCG
CATCGGCGAGGTCGCCAAGCTCTTCCTCGATGCCGGTGTCATCGTGCTCACCGCTTTCGTCTCCCCCTTTCGAGCCGACC
GTGACAAAGCCCGCAAGCTTGTAGATGTTGATGATTTCATCGAAATCCACTGTGCAGCGGACCTAAGCATTTGCGAAGAG
CGAGACACCAAAGGGCTTTATGCCAAAGCCAGGGCAGGCGAAATCAAAGATTTCACCGGTATTTCCAGCCCCTATGAAGA
GCCTGCGTCACCCGAACTAAAGATCAATACCGGTGAGCAAAGCCTGGACAGTTGCGTTGAGATCGTGCTCAAGACTCTGC
TGAATCGAAAGGTAATTCCCGCCAAGCATCAACCAGTGTCTTAA

Upstream 100 bases:

>100_bases
GGGCGACCAGGTGACCCTGGTGATGGACGTCCTGCAAAGCGAGGGCTTCCGTCCCAAACAAGCTGGTGGCTGAAAGGAGC
TGACAGATCAGCTAGGCGGA

Downstream 100 bases:

>100_bases
TACAACTCGCCACGGGAACGGCCAGCAATAACCCCAAGAGCTGCCCAAAACCAAATAATGCTCCTGTTCTGGCACCAATC
GGCAAGGCAATCAGCAACCA

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MENGSPINIKTMSSAPQGDTNPKGTNIVWHEASVDRQSRAQQRGHRSAILWFTGLSGSGKSTLANAVNAALFEQGLATYV
LDGDNIRHSLCKDLGFSDSDREENIRRIGEVAKLFLDAGVIVLTAFVSPFRADRDKARKLVDVDDFIEIHCAADLSICEE
RDTKGLYAKARAGEIKDFTGISSPYEEPASPELKINTGEQSLDSCVEIVLKTLLNRKVIPAKHQPVS

Sequences:

>Translated_227_residues
MENGSPINIKTMSSAPQGDTNPKGTNIVWHEASVDRQSRAQQRGHRSAILWFTGLSGSGKSTLANAVNAALFEQGLATYV
LDGDNIRHSLCKDLGFSDSDREENIRRIGEVAKLFLDAGVIVLTAFVSPFRADRDKARKLVDVDDFIEIHCAADLSICEE
RDTKGLYAKARAGEIKDFTGISSPYEEPASPELKINTGEQSLDSCVEIVLKTLLNRKVIPAKHQPVS
>Mature_227_residues
MENGSPINIKTMSSAPQGDTNPKGTNIVWHEASVDRQSRAQQRGHRSAILWFTGLSGSGKSTLANAVNAALFEQGLATYV
LDGDNIRHSLCKDLGFSDSDREENIRRIGEVAKLFLDAGVIVLTAFVSPFRADRDKARKLVDVDDFIEIHCAADLSICEE
RDTKGLYAKARAGEIKDFTGISSPYEEPASPELKINTGEQSLDSCVEIVLKTLLNRKVIPAKHQPVS

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI62912492, Length=204, Percent_Identity=48.5294117647059, Blast_Score=198, Evalue=4e-51,
Organism=Homo sapiens, GI34447231, Length=204, Percent_Identity=48.5294117647059, Blast_Score=198, Evalue=4e-51,
Organism=Homo sapiens, GI46094058, Length=224, Percent_Identity=45.0892857142857, Blast_Score=197, Evalue=4e-51,
Organism=Escherichia coli, GI1789107, Length=194, Percent_Identity=55.6701030927835, Blast_Score=226, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17542422, Length=206, Percent_Identity=48.0582524271845, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6322852, Length=198, Percent_Identity=49.4949494949495, Blast_Score=197, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24667032, Length=203, Percent_Identity=46.7980295566502, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24667028, Length=203, Percent_Identity=46.7980295566502, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24667036, Length=203, Percent_Identity=46.7980295566502, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI116007838, Length=203, Percent_Identity=46.7980295566502, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24667044, Length=203, Percent_Identity=46.7980295566502, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24667040, Length=202, Percent_Identity=47.029702970297, Blast_Score=181, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 24812; Mature: 24812

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENGSPINIKTMSSAPQGDTNPKGTNIVWHEASVDRQSRAQQRGHRSAILWFTGLSGSGK
CCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCH
STLANAVNAALFEQGLATYVLDGDNIRHSLCKDLGFSDSDREENIRRIGEVAKLFLDAGV
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IVLTAFVSPFRADRDKARKLVDVDDFIEIHCAADLSICEERDTKGLYAKARAGEIKDFTG
HHHHHHHHHHHCCHHHHHHHCCCHHHEEEEECCCHHHHHHCCCCCEEECCCCCCCHHHCC
ISSPYEEPASPELKINTGEQSLDSCVEIVLKTLLNRKVIPAKHQPVS
CCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MENGSPINIKTMSSAPQGDTNPKGTNIVWHEASVDRQSRAQQRGHRSAILWFTGLSGSGK
CCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCH
STLANAVNAALFEQGLATYVLDGDNIRHSLCKDLGFSDSDREENIRRIGEVAKLFLDAGV
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IVLTAFVSPFRADRDKARKLVDVDDFIEIHCAADLSICEERDTKGLYAKARAGEIKDFTG
HHHHHHHHHHHCCHHHHHHHCCCHHHEEEEECCCHHHHHHCCCCCEEECCCCCCCHHHCC
ISSPYEEPASPELKINTGEQSLDSCVEIVLKTLLNRKVIPAKHQPVS
CCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]