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The map label for this gene is holB [H]

Identifier: 33864254

GI number: 33864254

Start: 2102319

End: 2103299

Strand: Reverse

Name: holB [H]

Synonym: PMT1989

Alternate gene names: 33864254

Gene position: 2103299-2102319 (Counterclockwise)

Preceding gene: 33864255

Following gene: 33864250

Centisome position: 87.24

GC content: 55.66

Gene sequence:

>981_bases
ATGAGCCTTGAGATTGAGTCGCGTGGGCTGTTTGAAGATTTGATCGCTCAGCCGTTGGCAGTTGCATTGCTGGAGGCAGC
GTTGAGTCAGGGTCGACTGGCTCCCGCATATCTCTTTTCTGGTCCAGATGGAGTGGGTCGCAGTTTGGCGGCATTGCGTT
TTCTCGAGGGCCTCATCAGCAGTGGTAAGCCGGCCCTGCGTGAACGCCGTCGTCTAGAGGCGTTCAACCATCCTGATCTG
CTTTGGGTCGAACCGACTTATCAGCATCAAGGCCGCTTGGTCCCTAAGTCCCAGGCAGAGGAAGAAGGTGTCAACCGCCG
TTCCCCCCCACAGGTGCGCCTCGAACAGATTCGCGGGGTGACAAGATTCCTAGGACGACGACCTGTTGAGGCCCCAAGGG
GCATGGTCGTGATTGAAGCTTCAGAGTCTATGCCCGAAGCTGCTGCCAATGCTTTGCTTAAAACGCTGGAAGAACCAGGT
CATGGCTTGTTGATTCTGCTTTCGACCGCTTCTGAGCGCTTGCTCAAGACAATTCGCTCTCGATGCCAACAGATTCTTTT
TGCTCGTCTTGAAGCAGCTGACATGCAGGCTGCTCTGGCCAGGACGAGCACAGCTGAGATGGGGTCGTCCTTGTTGGCAT
TGGATCAGCCGGAACTGGTTGCGATGGCCGCTGGTTCTCCTGGGGCGCTGTTGCAGAATTTTGGGCTCTGGCAGGCAGTC
CCAGAGGAGTTTTGGCTACGGCTTGAAGAGCGTCCCCAAAAGCCAATGGAAGCCTTAGCTCTGGCGAGGGACCTTACGGA
GGCTCTTAATGGGGAGCAGCAGCTTTGGCTGATTGATTGGTGGCAACAACATTTTTGGATCCAACGGCCTGATCCAACAC
CACTGAAACGTTTGGAAAGGCTGCGTTCACACCTGCTGGGGTTTGTGCAACCCAGGCTGGCCTGGGAAGTGGCTTTGCTG
GAATTGATTCCTCGCGCTTAA

Upstream 100 bases:

>100_bases
CTTGGGTGCCGTTGCAGGCGGATCAACAAGTTGAGTCAGTTAGTTCTGCTTTGGAGAGCCAGCTGAAGCACCATTTTGGG
CCTTTGCAAGAGAGCATGCG

Downstream 100 bases:

>100_bases
GCGCTGGCGCGCTCTCCTTGCTTGTTTTGTGCTTCTCTGGCTTCCCTCTCTTGGCGTGCTTGGATTAGGAGGTCTTGGAT
CCCTTCGAGTTGTCCTCCTG

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSLEIESRGLFEDLIAQPLAVALLEAALSQGRLAPAYLFSGPDGVGRSLAALRFLEGLISSGKPALRERRRLEAFNHPDL
LWVEPTYQHQGRLVPKSQAEEEGVNRRSPPQVRLEQIRGVTRFLGRRPVEAPRGMVVIEASESMPEAAANALLKTLEEPG
HGLLILLSTASERLLKTIRSRCQQILFARLEAADMQAALARTSTAEMGSSLLALDQPELVAMAAGSPGALLQNFGLWQAV
PEEFWLRLEERPQKPMEALALARDLTEALNGEQQLWLIDWWQQHFWIQRPDPTPLKRLERLRSHLLGFVQPRLAWEVALL
ELIPRA

Sequences:

>Translated_326_residues
MSLEIESRGLFEDLIAQPLAVALLEAALSQGRLAPAYLFSGPDGVGRSLAALRFLEGLISSGKPALRERRRLEAFNHPDL
LWVEPTYQHQGRLVPKSQAEEEGVNRRSPPQVRLEQIRGVTRFLGRRPVEAPRGMVVIEASESMPEAAANALLKTLEEPG
HGLLILLSTASERLLKTIRSRCQQILFARLEAADMQAALARTSTAEMGSSLLALDQPELVAMAAGSPGALLQNFGLWQAV
PEEFWLRLEERPQKPMEALALARDLTEALNGEQQLWLIDWWQQHFWIQRPDPTPLKRLERLRSHLLGFVQPRLAWEVALL
ELIPRA
>Mature_325_residues
SLEIESRGLFEDLIAQPLAVALLEAALSQGRLAPAYLFSGPDGVGRSLAALRFLEGLISSGKPALRERRRLEAFNHPDLL
WVEPTYQHQGRLVPKSQAEEEGVNRRSPPQVRLEQIRGVTRFLGRRPVEAPRGMVVIEASESMPEAAANALLKTLEEPGH
GLLILLSTASERLLKTIRSRCQQILFARLEAADMQAALARTSTAEMGSSLLALDQPELVAMAAGSPGALLQNFGLWQAVP
EEFWLRLEERPQKPMEALALARDLTEALNGEQQLWLIDWWQQHFWIQRPDPTPLKRLERLRSHLLGFVQPRLAWEVALLE
LIPRA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36491; Mature: 36360

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEIESRGLFEDLIAQPLAVALLEAALSQGRLAPAYLFSGPDGVGRSLAALRFLEGLIS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
SGKPALRERRRLEAFNHPDLLWVEPTYQHQGRLVPKSQAEEEGVNRRSPPQVRLEQIRGV
CCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHH
TRFLGRRPVEAPRGMVVIEASESMPEAAANALLKTLEEPGHGLLILLSTASERLLKTIRS
HHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
RCQQILFARLEAADMQAALARTSTAEMGSSLLALDQPELVAMAAGSPGALLQNFGLWQAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCEEEEECCCCHHHHHHCCHHHHC
PEEFWLRLEERPQKPMEALALARDLTEALNGEQQLWLIDWWQQHFWIQRPDPTPLKRLER
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCEEEECCCCCHHHHHHH
LRSHLLGFVQPRLAWEVALLELIPRA
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLEIESRGLFEDLIAQPLAVALLEAALSQGRLAPAYLFSGPDGVGRSLAALRFLEGLIS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
SGKPALRERRRLEAFNHPDLLWVEPTYQHQGRLVPKSQAEEEGVNRRSPPQVRLEQIRGV
CCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHH
TRFLGRRPVEAPRGMVVIEASESMPEAAANALLKTLEEPGHGLLILLSTASERLLKTIRS
HHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
RCQQILFARLEAADMQAALARTSTAEMGSSLLALDQPELVAMAAGSPGALLQNFGLWQAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCEEEEECCCCHHHHHHCCHHHHC
PEEFWLRLEERPQKPMEALALARDLTEALNGEQQLWLIDWWQQHFWIQRPDPTPLKRLER
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCEEEECCCCCHHHHHHH
LRSHLLGFVQPRLAWEVALLELIPRA
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]