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The map label for this gene is kdsC [H]

Identifier: 33864178

GI number: 33864178

Start: 2018319

End: 2018915

Strand: Direct

Name: kdsC [H]

Synonym: PMT1912

Alternate gene names: 33864178

Gene position: 2018319-2018915 (Clockwise)

Preceding gene: 33864177

Following gene: 33864179

Centisome position: 83.72

GC content: 56.78

Gene sequence:

>597_bases
ATGAGCGGCACTACCCTGATCTCTCGAACCCACCCCCGTTACTGGAACCGAGAGCTGCAATGGCGACTGCAGTGGAAGGC
ATTAGCTTCCATCGATCTACTGGTGATGGATGTTGATGGAGTCCTTACCGATGGTGGGCTATGGCTTGATGCTCACGGCG
AACTGCAAAAGCGATTTGATGTGCGCGATGGACTGGGACTACGACTGCTCCAACAAGAAGGCCTGACACTAGCCTTGCTG
AGTGGTGGCAAAGGAGGAGCGACCGAGGCGCGCGCCAAGCAGCTCGGCATTCAGCACTGTTTCGTTGGCATCAAAGACAA
AACCGCCGCACTCGCAGAACTGCAGCAACAGCTCAACCTGTCGCAATTAAACACCGCATTTGTCGGCGATGACCTCAATG
ACCTCATCGTGCGCCCTCTGGTCAAGCTTTTGCTAGCCCCTGCGGATGCCTGTCGTCCCCTCCGATCTCAAGCCGATGCC
GTACTCCAGCGCCGTGGGGGGCATGGTGCCGTGCGAGAACTCGCAGAACGCCTACTAAAAGCCCGTGGTCAATGGCATCA
ACTGCGCAAGAAAGGCTGGAAGGAGCGCAATGACTAA

Upstream 100 bases:

>100_bases
GCAAACCCATCTCAGTACTGCCCGTCGTAGGCCCTGACAGCTCAGGCAATCTGTTGCTCGGACTACTACGGCTTCATGAT
CTGATTCAAGCAGGGCTGAC

Downstream 100 bases:

>100_bases
AACAAACTCGACGACACAACAAGGGGTCTTCCTTCTCGGGGTTGGCGCGCAAAAAGCCGGCACGTCGTGACTCCATCTAC
AGCTACATAACAGAGCCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSGTTLISRTHPRYWNRELQWRLQWKALASIDLLVMDVDGVLTDGGLWLDAHGELQKRFDVRDGLGLRLLQQEGLTLALL
SGGKGGATEARAKQLGIQHCFVGIKDKTAALAELQQQLNLSQLNTAFVGDDLNDLIVRPLVKLLLAPADACRPLRSQADA
VLQRRGGHGAVRELAERLLKARGQWHQLRKKGWKERND

Sequences:

>Translated_198_residues
MSGTTLISRTHPRYWNRELQWRLQWKALASIDLLVMDVDGVLTDGGLWLDAHGELQKRFDVRDGLGLRLLQQEGLTLALL
SGGKGGATEARAKQLGIQHCFVGIKDKTAALAELQQQLNLSQLNTAFVGDDLNDLIVRPLVKLLLAPADACRPLRSQADA
VLQRRGGHGAVRELAERLLKARGQWHQLRKKGWKERND
>Mature_197_residues
SGTTLISRTHPRYWNRELQWRLQWKALASIDLLVMDVDGVLTDGGLWLDAHGELQKRFDVRDGLGLRLLQQEGLTLALLS
GGKGGATEARAKQLGIQHCFVGIKDKTAALAELQQQLNLSQLNTAFVGDDLNDLIVRPLVKLLLAPADACRPLRSQADAV
LQRRGGHGAVRELAERLLKARGQWHQLRKKGWKERND

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=152, Percent_Identity=29.6052631578947, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI2367202, Length=160, Percent_Identity=40.625, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 22095; Mature: 21964

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTTLISRTHPRYWNRELQWRLQWKALASIDLLVMDVDGVLTDGGLWLDAHGELQKRFD
CCCCCEEECCCCCCCCCHHHEEEHHHHHHHHEEEEEECCCEEECCCEEEECCCHHHHHHC
VRDGLGLRLLQQEGLTLALLSGGKGGATEARAKQLGIQHCFVGIKDKTAALAELQQQLNL
CCCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCH
SQLNTAFVGDDLNDLIVRPLVKLLLAPADACRPLRSQADAVLQRRGGHGAVRELAERLLK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ARGQWHQLRKKGWKERND
HCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGTTLISRTHPRYWNRELQWRLQWKALASIDLLVMDVDGVLTDGGLWLDAHGELQKRFD
CCCCEEECCCCCCCCCHHHEEEHHHHHHHHEEEEEECCCEEECCCEEEECCCHHHHHHC
VRDGLGLRLLQQEGLTLALLSGGKGGATEARAKQLGIQHCFVGIKDKTAALAELQQQLNL
CCCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCH
SQLNTAFVGDDLNDLIVRPLVKLLLAPADACRPLRSQADAVLQRRGGHGAVRELAERLLK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ARGQWHQLRKKGWKERND
HCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]