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The map label for this gene is cysD [H]

Identifier: 33864066

GI number: 33864066

Start: 1901008

End: 1902180

Strand: Reverse

Name: cysD [H]

Synonym: PMT1799

Alternate gene names: 33864066

Gene position: 1902180-1901008 (Counterclockwise)

Preceding gene: 33864067

Following gene: 33864065

Centisome position: 78.9

GC content: 54.39

Gene sequence:

>1173_bases
ATGATTGCCAGTCCCTCTGCATCTGCCCAGTCTCCAGGCGTGATCGCCCCCTATGGAGGGAAACTGGTGGATTTGATGGT
GGCTACTGATCAGCAAGAAGCTGTCAAGGCCAGTGCCAACTATGTGTTGGAGTGTTCAGATCGCAATGCTTGCGATCTGG
AGTTGCTTGTCGGTGGAGGCTTTTCGCCTGAGCGGGGCTTTATGCACCAGGGTGATTACGACGCTGTTGTTGCAGGCCAT
CGCACTCTTTCCGGCTATCTTTTCGGCCTGCCAATCGTGATGGATACCGATCGAGAGGATGTAGCGATCGGTGATCGGGT
GTTGCTGAGTTACAAGGGTCAGGATTTGGCAGTTCTCCAAGTCGAGGACAAATGGGAGCCCGACAAGGTTGTGGAAGCCA
AAGGTTGCTATGGCACCACCTCTCTAGAACATCCCGCTGTGCGCATGATTGCCACGGAACGCAAGCGCTTTTATCTCGGG
GGCACCTTGCAGGGTTTGGAGTTGCCCAAGCGTATTTTCCCTTGCAAGAGCCCTGCTCAGGTTCGGGCGGAACTTCCTGC
CGGGGAGGACGTTGTTGCCTTTCAGTGTCGCAATCCTATTCATCGTGCTCACTACGAGTTGTTTACGCGAGCCTTGCATG
CCAGCAATGTGAGCGAGAACGCAGTTGTGCTAGTGCATCCCACCTGTGGACCAACTCAGGAGGATGATATCCCTGGCGGG
GTACGTTTTCAGACCTATGAGCGGTTGGCTGCGGAGGTAGATAATCCCCGCATTCGCTGGGCCTATCTTCCCTATGCCAT
GCATATGGCAGGTCCGCGCGAAGCCCTGCAACACATGATTATTCGCCGCAATTATGGATGTACCCATTTCATCATTGGTC
GTGACATGGCCGGATGTAAGTCCTCCCTTAGCGGCGATGACTTCTATGGCCCTTACGACGCGCAGAACTTTGCACAGGAA
TGTGCAGTAGAGCTGGCAATGGAAACGGTACCCTCGTTGAATCTTGTTTTCACTGAAGAGGAGGGCTACGTCACTGCTGA
GCATGCCGAGGCTCGTGGATTACATGTCAAGAAGCTCAGCGGTACGCAGTTTCGCAAGATGTTGAGAAGTGGCGAGGAGA
TCCCTGAGTGGTTCGCCTTCCGTAGCGTGGTTGAGGTGCTGAGAGCCACGTGA

Upstream 100 bases:

>100_bases
GCCTATGGGCCCCTTTTTTTGACCATGATTTAGTTGCGTCTGGTCTTAGCTGATCAAAACCAGCCGTCTGGGAGAATCTC
CCGGCATCCTCAGGCTTGTC

Downstream 100 bases:

>100_bases
TTCCCTTAGCCCGAATAACATTCTTTCATTACAGGCAGGAGAATCTTGGATAAACGCTGGCGCAACGTAGGTCTTTACGT
TCTTCTGGTGGTCGTGGTGG

Product: ATP-sulfurylase

Products: NA

Alternate protein names: Sulfate adenylyltransferase; ATP-sulfurylase; Sulfate adenylate transferase; SAT; Adenylyl-sulfate kinase; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MIASPSASAQSPGVIAPYGGKLVDLMVATDQQEAVKASANYVLECSDRNACDLELLVGGGFSPERGFMHQGDYDAVVAGH
RTLSGYLFGLPIVMDTDREDVAIGDRVLLSYKGQDLAVLQVEDKWEPDKVVEAKGCYGTTSLEHPAVRMIATERKRFYLG
GTLQGLELPKRIFPCKSPAQVRAELPAGEDVVAFQCRNPIHRAHYELFTRALHASNVSENAVVLVHPTCGPTQEDDIPGG
VRFQTYERLAAEVDNPRIRWAYLPYAMHMAGPREALQHMIIRRNYGCTHFIIGRDMAGCKSSLSGDDFYGPYDAQNFAQE
CAVELAMETVPSLNLVFTEEEGYVTAEHAEARGLHVKKLSGTQFRKMLRSGEEIPEWFAFRSVVEVLRAT

Sequences:

>Translated_390_residues
MIASPSASAQSPGVIAPYGGKLVDLMVATDQQEAVKASANYVLECSDRNACDLELLVGGGFSPERGFMHQGDYDAVVAGH
RTLSGYLFGLPIVMDTDREDVAIGDRVLLSYKGQDLAVLQVEDKWEPDKVVEAKGCYGTTSLEHPAVRMIATERKRFYLG
GTLQGLELPKRIFPCKSPAQVRAELPAGEDVVAFQCRNPIHRAHYELFTRALHASNVSENAVVLVHPTCGPTQEDDIPGG
VRFQTYERLAAEVDNPRIRWAYLPYAMHMAGPREALQHMIIRRNYGCTHFIIGRDMAGCKSSLSGDDFYGPYDAQNFAQE
CAVELAMETVPSLNLVFTEEEGYVTAEHAEARGLHVKKLSGTQFRKMLRSGEEIPEWFAFRSVVEVLRAT
>Mature_390_residues
MIASPSASAQSPGVIAPYGGKLVDLMVATDQQEAVKASANYVLECSDRNACDLELLVGGGFSPERGFMHQGDYDAVVAGH
RTLSGYLFGLPIVMDTDREDVAIGDRVLLSYKGQDLAVLQVEDKWEPDKVVEAKGCYGTTSLEHPAVRMIATERKRFYLG
GTLQGLELPKRIFPCKSPAQVRAELPAGEDVVAFQCRNPIHRAHYELFTRALHASNVSENAVVLVHPTCGPTQEDDIPGG
VRFQTYERLAAEVDNPRIRWAYLPYAMHMAGPREALQHMIIRRNYGCTHFIIGRDMAGCKSSLSGDDFYGPYDAQNFAQE
CAVELAMETVPSLNLVFTEEEGYVTAEHAEARGLHVKKLSGTQFRKMLRSGEEIPEWFAFRSVVEVLRAT

Specific function: Unknown

COG id: COG2046

COG function: function code P; ATP sulfurylase (sulfate adenylyltransferase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=348, Percent_Identity=28.448275862069, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI62912492, Length=403, Percent_Identity=27.0471464019851, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI34447231, Length=398, Percent_Identity=27.1356783919598, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17542422, Length=404, Percent_Identity=27.7227722772277, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322469, Length=390, Percent_Identity=37.9487179487179, Blast_Score=257, Evalue=2e-69,
Organism=Drosophila melanogaster, GI116007838, Length=398, Percent_Identity=25.3768844221106, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667044, Length=398, Percent_Identity=25.3768844221106, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667040, Length=398, Percent_Identity=25.3768844221106, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24667032, Length=398, Percent_Identity=25.3768844221106, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24667028, Length=398, Percent_Identity=25.3768844221106, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24667036, Length=398, Percent_Identity=25.3768844221106, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR020792
- InterPro:   IPR002650 [H]

Pfam domain/function: PF01583 APS_kinase; PF01747 ATP-sulfurylase [H]

EC number: =2.7.7.4; =2.7.1.25 [H]

Molecular weight: Translated: 43103; Mature: 43103

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASPSASAQSPGVIAPYGGKLVDLMVATDQQEAVKASANYVLECSDRNACDLELLVGGG
CCCCCCCCCCCCCEEECCCCCEEEEEEECCHHHHHHHCCCEEEEECCCCCCEEEEEECCC
FSPERGFMHQGDYDAVVAGHRTLSGYLFGLPIVMDTDREDVAIGDRVLLSYKGQDLAVLQ
CCCCCCCCCCCCCCEEEECCCEECEEEEECCEEEECCCCCEECCCEEEEEECCCCEEEEE
VEDKWEPDKVVEAKGCYGTTSLEHPAVRMIATERKRFYLGGTLQGLELPKRIFPCKSPAQ
ECCCCCCCCEEECCCCCCCCCCCCCHHHHEECCCCEEEECCEECCCCCHHHHCCCCCHHH
VRAELPAGEDVVAFQCRNPIHRAHYELFTRALHASNVSENAVVLVHPTCGPTQEDDIPGG
HEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
VRFQTYERLAAEVDNPRIRWAYLPYAMHMAGPREALQHMIIRRNYGCTHFIIGRDMAGCK
CCHHHHHHHHHHCCCCEEEEEECCCHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHH
SSLSGDDFYGPYDAQNFAQECAVELAMETVPSLNLVFTEEEGYVTAEHAEARGLHVKKLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCCCEEEECC
GTQFRKMLRSGEEIPEWFAFRSVVEVLRAT
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIASPSASAQSPGVIAPYGGKLVDLMVATDQQEAVKASANYVLECSDRNACDLELLVGGG
CCCCCCCCCCCCCEEECCCCCEEEEEEECCHHHHHHHCCCEEEEECCCCCCEEEEEECCC
FSPERGFMHQGDYDAVVAGHRTLSGYLFGLPIVMDTDREDVAIGDRVLLSYKGQDLAVLQ
CCCCCCCCCCCCCCEEEECCCEECEEEEECCEEEECCCCCEECCCEEEEEECCCCEEEEE
VEDKWEPDKVVEAKGCYGTTSLEHPAVRMIATERKRFYLGGTLQGLELPKRIFPCKSPAQ
ECCCCCCCCEEECCCCCCCCCCCCCHHHHEECCCCEEEECCEECCCCCHHHHCCCCCHHH
VRAELPAGEDVVAFQCRNPIHRAHYELFTRALHASNVSENAVVLVHPTCGPTQEDDIPGG
HEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
VRFQTYERLAAEVDNPRIRWAYLPYAMHMAGPREALQHMIIRRNYGCTHFIIGRDMAGCK
CCHHHHHHHHHHCCCCEEEEEECCCHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHH
SSLSGDDFYGPYDAQNFAQECAVELAMETVPSLNLVFTEEEGYVTAEHAEARGLHVKKLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCCCEEEECC
GTQFRKMLRSGEEIPEWFAFRSVVEVLRAT
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]