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The map label for this gene is aroC

Identifier: 33864062

GI number: 33864062

Start: 1896145

End: 1897233

Strand: Direct

Name: aroC

Synonym: PMT1795

Alternate gene names: 33864062

Gene position: 1896145-1897233 (Clockwise)

Preceding gene: 33864060

Following gene: 33864068

Centisome position: 78.65

GC content: 55.46

Gene sequence:

>1089_bases
ATGGGCAGCAGCTTTGGGGATCTATTCCGAATCAGCACCTTCGGTGAATCTCATGGAGGGGGCGTGGGAGTCATCGTGGA
AGGCTGCCCACCAAGGCTTGAGCTTGACCTACAGAAGATTCAGGCCGAGCTAGATCGACGCAAACCTGGCCAAAGCAAGA
TCAGTACACCCCGCAAGGAAGAAGATCAAGTCGAAATCCTCAGCGGTCTGCTCAACAACACAACCCTTGGGACACCAATC
GCCATGGTGGTGCGCAACAAGGATCACAAGCCTGGCGACTACAAGGAGATGAATGTTGCATTTCGGCCTTCCCATGCCGA
TGCCACCTATCAGGCGAAGTACGGCATCCAAGCTCGAAGCGGTGGAGGGCGAGCCTCCGCAAGAGAGACGATTGCGCGGG
TAGCCGCTGGAGCGATTGCCAAGCAATTACTGACCAAAGCCCATAACACCGAAGTACTGGCATGGGTCAAACGCATTCAC
ACCCTGGAGGCCGAAATCAATGCCCAAGACGTCAGCATTGATGACGTAGAAGCAAACATCGTGCGTTGCCCGAACCAAGT
CATGGCAGCGCAAATGGTGGAGCGTATTGAAGCCATCAGCCGTGAAGGCGACTCATGCGGTGGTGTGATCGAGTGTGTTG
TCCGCAATGCCCCAATGGGTCTGGGGATGCCTGTGTTTGACAAGCTTGAGGCAGACCTCGCCAAGGCCGTGATGTCACTA
CCTGCCAGCAAGGGCTTTGAGATCGGCTCGGGTTTTGGCGGCACCCTGCTAAAAGGCAGCGAGCACAACGACGCTTTCCT
CCCCAGCAATGATGGTCGCCTACGAACAGCCACCAACAACTCTGGTGGCATCCAGGGAGGGATCACTAACGGTGAATCGA
TCGTGATCCGAGTGGCGTTCAAGCCAACAGCCACCATCCGCAAAGATCAACAAACAATTGACGCTGATGGCAACACCACG
ACACTGTCTGCCAAAGGTCGTCATGATCCCTGCGTGCTGCCTAGGGCCGTACCGATAGTTGAAGCCATGGTGTCCCTTGT
ACTCGCTGATCACCTCTTACGCCAACAAGGACAGTGCAGTCTCTGGTAA

Upstream 100 bases:

>100_bases
AAGCCGTTGTCTCTGAAACTCCCGGCATCAATTGAAGATGAGCAAAGCAAGCTCCCCGCTGCGCAGCGACTAATTACTCT
CTAATAAGAATGAGTTCTTG

Downstream 100 bases:

>100_bases
AGCAAATCTGCGCCTACCTAGACCAAGCAATGATTCCCCCTTCACAAGGTCCTACTACTCAATCATCATCGACAAATAGT
TAAAGCATGCGCTGCCAATG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGSSFGDLFRISTFGESHGGGVGVIVEGCPPRLELDLQKIQAELDRRKPGQSKISTPRKEEDQVEILSGLLNNTTLGTPI
AMVVRNKDHKPGDYKEMNVAFRPSHADATYQAKYGIQARSGGGRASARETIARVAAGAIAKQLLTKAHNTEVLAWVKRIH
TLEAEINAQDVSIDDVEANIVRCPNQVMAAQMVERIEAISREGDSCGGVIECVVRNAPMGLGMPVFDKLEADLAKAVMSL
PASKGFEIGSGFGGTLLKGSEHNDAFLPSNDGRLRTATNNSGGIQGGITNGESIVIRVAFKPTATIRKDQQTIDADGNTT
TLSAKGRHDPCVLPRAVPIVEAMVSLVLADHLLRQQGQCSLW

Sequences:

>Translated_362_residues
MGSSFGDLFRISTFGESHGGGVGVIVEGCPPRLELDLQKIQAELDRRKPGQSKISTPRKEEDQVEILSGLLNNTTLGTPI
AMVVRNKDHKPGDYKEMNVAFRPSHADATYQAKYGIQARSGGGRASARETIARVAAGAIAKQLLTKAHNTEVLAWVKRIH
TLEAEINAQDVSIDDVEANIVRCPNQVMAAQMVERIEAISREGDSCGGVIECVVRNAPMGLGMPVFDKLEADLAKAVMSL
PASKGFEIGSGFGGTLLKGSEHNDAFLPSNDGRLRTATNNSGGIQGGITNGESIVIRVAFKPTATIRKDQQTIDADGNTT
TLSAKGRHDPCVLPRAVPIVEAMVSLVLADHLLRQQGQCSLW
>Mature_361_residues
GSSFGDLFRISTFGESHGGGVGVIVEGCPPRLELDLQKIQAELDRRKPGQSKISTPRKEEDQVEILSGLLNNTTLGTPIA
MVVRNKDHKPGDYKEMNVAFRPSHADATYQAKYGIQARSGGGRASARETIARVAAGAIAKQLLTKAHNTEVLAWVKRIHT
LEAEINAQDVSIDDVEANIVRCPNQVMAAQMVERIEAISREGDSCGGVIECVVRNAPMGLGMPVFDKLEADLAKAVMSLP
ASKGFEIGSGFGGTLLKGSEHNDAFLPSNDGRLRTATNNSGGIQGGITNGESIVIRVAFKPTATIRKDQQTIDADGNTTT
LSAKGRHDPCVLPRAVPIVEAMVSLVLADHLLRQQGQCSLW

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=45.6582633053221, Blast_Score=289, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=54.4959128065395, Blast_Score=391, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_PROM3 (A2CCA2)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001018377.1
- ProteinModelPortal:   A2CCA2
- SMR:   A2CCA2
- STRING:   A2CCA2
- GeneID:   4776524
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_23791
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38715; Mature: 38583

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSFGDLFRISTFGESHGGGVGVIVEGCPPRLELDLQKIQAELDRRKPGQSKISTPRKE
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
EDQVEILSGLLNNTTLGTPIAMVVRNKDHKPGDYKEMNVAFRPSHADATYQAKYGIQARS
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEECCEEECC
GGGRASARETIARVAAGAIAKQLLTKAHNTEVLAWVKRIHTLEAEINAQDVSIDDVEANI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VRCPNQVMAAQMVERIEAISREGDSCGGVIECVVRNAPMGLGMPVFDKLEADLAKAVMSL
HHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
PASKGFEIGSGFGGTLLKGSEHNDAFLPSNDGRLRTATNNSGGIQGGITNGESIVIRVAF
CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEE
KPTATIRKDQQTIDADGNTTTLSAKGRHDPCVLPRAVPIVEAMVSLVLADHLLRQQGQCS
CCCCHHCCCCCEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
LW
CC
>Mature Secondary Structure 
GSSFGDLFRISTFGESHGGGVGVIVEGCPPRLELDLQKIQAELDRRKPGQSKISTPRKE
CCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
EDQVEILSGLLNNTTLGTPIAMVVRNKDHKPGDYKEMNVAFRPSHADATYQAKYGIQARS
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEECCEEECC
GGGRASARETIARVAAGAIAKQLLTKAHNTEVLAWVKRIHTLEAEINAQDVSIDDVEANI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VRCPNQVMAAQMVERIEAISREGDSCGGVIECVVRNAPMGLGMPVFDKLEADLAKAVMSL
HHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
PASKGFEIGSGFGGTLLKGSEHNDAFLPSNDGRLRTATNNSGGIQGGITNGESIVIRVAF
CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEE
KPTATIRKDQQTIDADGNTTTLSAKGRHDPCVLPRAVPIVEAMVSLVLADHLLRQQGQCS
CCCCHHCCCCCEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
LW
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA