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The map label for this gene is dapL [H]

Identifier: 33864058

GI number: 33864058

Start: 1891858

End: 1893111

Strand: Direct

Name: dapL [H]

Synonym: PMT1791

Alternate gene names: 33864058

Gene position: 1891858-1893111 (Clockwise)

Preceding gene: 33864054

Following gene: 33864059

Centisome position: 78.47

GC content: 56.78

Gene sequence:

>1254_bases
ATGCCTGCCAAGACTGCCAGCTCATCAGTGGTTCAGGTCAACAGCAACTACCTCAAACTCAAGGCGGGATATCTATTCCC
CGAAATCGCCAGGCGGATCAAAAGCTTCAGTGAAGCCAACCCGGATGCTGCGCTCATCCGCCTCGGCATCGGCGATGTAA
CCGAACCTCTGCCACTGGCATGTAGAAACGCGATGAAGGTAGCCATCGACGAGATGGGGACCAACACTGGCTTCCATGGC
TATGGCCCTGAGCAGGGCTACGACTGGCTGCGCAAAGCGATCGCCAAGCATGATTTCCAGACCAAAGGCTGTCAGATCAA
TGCCGAGGAGATCTTTGTCTCCGACGGATCGAAGTGCGACAGCAGCAACATCCTCGACATCCTTGGGAGCAGCAATCGCA
TCGCCGTTACAGATCCGGTTTATCCGGTCTATGTCGACAGCAACGTGATGGCGGGTCGCACCGGCGACGCCAATCAAAGC
GGCCGCTACGCAGGCCTGAGCTACCTGCCAATCAACGCCGAAAATGGGTTTGCAGCCAAGATCCCCTCCGAACCAGTCGA
TCTGATCTATCTGTGTTTCCCCAACAACCCCACCGGAGCGGTAGCCACAAGAGCCCAGCTCCAGGAGTGGGTGAACTATG
CCCGCACCAACAGTGTCTTGATTTTGTTTGACGCTGCCTATGAGGCGTTCATCCAGAACCCCGACCTGCCGCATTCGATC
TATGAGATCGAGGGCGCTCGCGAGTGTGCCATCGAATTCAGATCGTTCTCCAAGAATGCTGGATTCACCGGCACCCGTTG
CGCCTTCACGGTGGTACCGAAAGGCTTGAAGGGCAAAAGCGACGATGGATCAGATGTGGAACTCTGGAATCTCTGGAACA
GGCGCCAAAGCACCAAGTTCAACGGAGTCAGCTACATCATTCAGCGTGGCGCCGAAGCGGTTTACTCCGCCCAAGGCCAG
GGAGAGATCAATGCGCTAGTGAGCTTCTACATGAGAAACGCCGCCATCATCCGCAGGGAACTTACGGCCGCCGGGATCGA
AGTGCATGGTGGTGAGCATGCGCCCTATGTGTGGCTGAAGACACCAGACGACATGGATTCCTGGGGCTTCTTCGATCATC
TGCTCCAAAATGCCCACGTGGTAGGCACCCCAGGCAGCGGTTTCGGTGCTGCAGGCGAAGGCTACTTCCGTCTCTCCGCC
TTCAACAGTCGCGTCAATGTAGACGAAGCCATGCGTCGGATCCGTGCCCTCTGA

Upstream 100 bases:

>100_bases
GGGGTGAGGCGACGGTCATGGCCAAGAGGGCACTAATCCCATCGTATGGACAACGCTGGCCACCCCCCCGACACAGCGCA
AGGCCCCGTGACGTAGCAAG

Downstream 100 bases:

>100_bases
GACCACAGAATCAATCCCCCGCCATTGAAGCTGGGATTGCCCACCATCTGCACCATGGGTGAGCGGCCCACGTACATTGG
AGCCGTCCCGATCGTCCTGG

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MPAKTASSSVVQVNSNYLKLKAGYLFPEIARRIKSFSEANPDAALIRLGIGDVTEPLPLACRNAMKVAIDEMGTNTGFHG
YGPEQGYDWLRKAIAKHDFQTKGCQINAEEIFVSDGSKCDSSNILDILGSSNRIAVTDPVYPVYVDSNVMAGRTGDANQS
GRYAGLSYLPINAENGFAAKIPSEPVDLIYLCFPNNPTGAVATRAQLQEWVNYARTNSVLILFDAAYEAFIQNPDLPHSI
YEIEGARECAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKSDDGSDVELWNLWNRRQSTKFNGVSYIIQRGAEAVYSAQGQ
GEINALVSFYMRNAAIIRRELTAAGIEVHGGEHAPYVWLKTPDDMDSWGFFDHLLQNAHVVGTPGSGFGAAGEGYFRLSA
FNSRVNVDEAMRRIRAL

Sequences:

>Translated_417_residues
MPAKTASSSVVQVNSNYLKLKAGYLFPEIARRIKSFSEANPDAALIRLGIGDVTEPLPLACRNAMKVAIDEMGTNTGFHG
YGPEQGYDWLRKAIAKHDFQTKGCQINAEEIFVSDGSKCDSSNILDILGSSNRIAVTDPVYPVYVDSNVMAGRTGDANQS
GRYAGLSYLPINAENGFAAKIPSEPVDLIYLCFPNNPTGAVATRAQLQEWVNYARTNSVLILFDAAYEAFIQNPDLPHSI
YEIEGARECAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKSDDGSDVELWNLWNRRQSTKFNGVSYIIQRGAEAVYSAQGQ
GEINALVSFYMRNAAIIRRELTAAGIEVHGGEHAPYVWLKTPDDMDSWGFFDHLLQNAHVVGTPGSGFGAAGEGYFRLSA
FNSRVNVDEAMRRIRAL
>Mature_416_residues
PAKTASSSVVQVNSNYLKLKAGYLFPEIARRIKSFSEANPDAALIRLGIGDVTEPLPLACRNAMKVAIDEMGTNTGFHGY
GPEQGYDWLRKAIAKHDFQTKGCQINAEEIFVSDGSKCDSSNILDILGSSNRIAVTDPVYPVYVDSNVMAGRTGDANQSG
RYAGLSYLPINAENGFAAKIPSEPVDLIYLCFPNNPTGAVATRAQLQEWVNYARTNSVLILFDAAYEAFIQNPDLPHSIY
EIEGARECAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKSDDGSDVELWNLWNRRQSTKFNGVSYIIQRGAEAVYSAQGQG
EINALVSFYMRNAAIIRRELTAAGIEVHGGEHAPYVWLKTPDDMDSWGFFDHLLQNAHVVGTPGSGFGAAGEGYFRLSAF
NSRVNVDEAMRRIRAL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=344, Percent_Identity=26.7441860465116, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 45628; Mature: 45497

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKTASSSVVQVNSNYLKLKAGYLFPEIARRIKSFSEANPDAALIRLGIGDVTEPLPLA
CCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHH
CRNAMKVAIDEMGTNTGFHGYGPEQGYDWLRKAIAKHDFQTKGCQINAEEIFVSDGSKCD
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHEEEEECCCCCC
SSNILDILGSSNRIAVTDPVYPVYVDSNVMAGRTGDANQSGRYAGLSYLPINAENGFAAK
CCCHHHHCCCCCEEEEECCCEEEEECCCEEECCCCCCCCCCCCCCEEEEEEECCCCEEEE
IPSEPVDLIYLCFPNNPTGAVATRAQLQEWVNYARTNSVLILFDAAYEAFIQNPDLPHSI
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCHH
YEIEGARECAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKSDDGSDVELWNLWNRRQSTKF
EEECCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHCCCCCCCC
NGVSYIIQRGAEAVYSAQGQGEINALVSFYMRNAAIIRRELTAAGIEVHGGEHAPYVWLK
CHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEE
TPDDMDSWGFFDHLLQNAHVVGTPGSGFGAAGEGYFRLSAFNSRVNVDEAMRRIRAL
CCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PAKTASSSVVQVNSNYLKLKAGYLFPEIARRIKSFSEANPDAALIRLGIGDVTEPLPLA
CCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHH
CRNAMKVAIDEMGTNTGFHGYGPEQGYDWLRKAIAKHDFQTKGCQINAEEIFVSDGSKCD
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHEEEEECCCCCC
SSNILDILGSSNRIAVTDPVYPVYVDSNVMAGRTGDANQSGRYAGLSYLPINAENGFAAK
CCCHHHHCCCCCEEEEECCCEEEEECCCEEECCCCCCCCCCCCCCEEEEEEECCCCEEEE
IPSEPVDLIYLCFPNNPTGAVATRAQLQEWVNYARTNSVLILFDAAYEAFIQNPDLPHSI
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCHH
YEIEGARECAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKSDDGSDVELWNLWNRRQSTKF
EEECCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHCCCCCCCC
NGVSYIIQRGAEAVYSAQGQGEINALVSFYMRNAAIIRRELTAAGIEVHGGEHAPYVWLK
CHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEE
TPDDMDSWGFFDHLLQNAHVVGTPGSGFGAAGEGYFRLSAFNSRVNVDEAMRRIRAL
CCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA