Click here to switch to the map view.

The map label for this gene is secY [H]

Identifier: 33864017

GI number: 33864017

Start: 1844503

End: 1845822

Strand: Direct

Name: secY [H]

Synonym: PMT1750

Alternate gene names: 33864017

Gene position: 1844503-1845822 (Clockwise)

Preceding gene: 33864016

Following gene: 33864018

Centisome position: 76.51

GC content: 52.65

Gene sequence:

>1320_bases
ATGTTCGTCAGTCGGGGTCGCAACCCCAGTGCCGCTGAAGTCATAAGCCAATTGGTGCGCAACCCAGAGCTGCGCGGCAG
AGTGCTGACCACACTGGGATTACTTCTTTTTATTCGCCTCGGCATCTACATCCCAATGCCAGGTATTGATCGGGTGGCCT
TTCAAAGCTTCCTACAACAGGGCGGACAACTGATCGGCTTTCTAGATATTTTCACCGGTGGAGGCATCTCCACCCTGGGG
ATTTTCGCTCTTGGGATCCTCCCATTCATCAACGCCTCAATCATTCTCCAGTTACTCACCGCAGCCTTACCCCAACTCGA
GGACCTGCAAAAAAACGAAGGCGAGGCTGGTCGTCGCAAGATCGCACAGATCACCCGCTATGTAGCTCTTGGCTGGGGTC
TAGTTCAAAGTGTGATTTTTGCCCTGATCCTCCGCCAGTACGCCGTTGAAGGGCTCAGTGAGGTCGTCTTTGTCGTGCAG
ACAGCCCTGGCATTAGTAACAGGCTCGATGATCGTGATGTGGATGAGCGAAATCATCACTGACCGAGGGATTGGTCAAGG
GGCCTCCCTTGTGATCTTCCTGAACATCGTTGCCACCCTGCCAAAAGCACTGGCTTCAACAATTGAAAAAGCACAAACCG
GCGATCGCGGCGATGTGGTCGGCATCATTGTGCTCGTGATGGTTTTCCTAATGACAATCGTTGGGATCATCTTCGTGCAG
GAAGGATCACGCCGTCTGCCGATTGTGAGCGCAAAAAGACAGATAGGTGGAACCAATTTGCTACCAAACCGCCAGAGCTA
TCTACCTCTGAAGCTGAATGCTGGTGGTGTGATGCCAATCATCTTTGCTTCTGCACTGATCTTTCTACCAATCACCATTG
CAAACTTCACCAAAAACCCTTTACTCATCAGGGCTGCAAGCACTCTTAACCCAAGTGCCGCTAATCCATGGCCCTATGCC
TTGGTGTTTTTCGCGCTGATTGTCGGCTTTTCTTACTTTTACGCCTCACTCACCATCAATCCAATAGACATCGCCACAAA
CCTCAAACGGGGAGGCGTGGCCATCCCAGGAGTGAGGCCAGGCAGTGCTACAGCGAACTACCTATCCGGAGTTCAGAACC
GACTGACCCTGCTGGGCGGATTGTTCCTCGGTGCAGTTGCGATCATTCCCGCCGCGGTGGAACGCGCCACCAACGTTCAG
ACCTTTCAAGGCCTCGGAGCTACGTCACTGCTGATCCTTGTAGGTGTTGCCATCGACACCGCAAAACAAGTTCAGACCTA
TGTGATTTCTCAACGCTACGAAGGCCTTGTCCGCCAATGA

Upstream 100 bases:

>100_bases
CCAAGTCAATACACCTGGATATCTATGGTCTGAGCAGTCCGATAAGTCTTCAGTCAACGGACTGCTCTATTGCTTCAAAC
CCACCCAATCCCTTCTCTCA

Downstream 100 bases:

>100_bases
ACCATTCCCCACTCCGTCTGAAAGCCCTTTTTTGCCATCCATGAAGCAACGTCTCCTATTCCTAGGGCCCCCTGGCGCAG
GCAAAGGGACCCAGGCTGAA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFVSRGRNPSAAEVISQLVRNPELRGRVLTTLGLLLFIRLGIYIPMPGIDRVAFQSFLQQGGQLIGFLDIFTGGGISTLG
IFALGILPFINASIILQLLTAALPQLEDLQKNEGEAGRRKIAQITRYVALGWGLVQSVIFALILRQYAVEGLSEVVFVVQ
TALALVTGSMIVMWMSEIITDRGIGQGASLVIFLNIVATLPKALASTIEKAQTGDRGDVVGIIVLVMVFLMTIVGIIFVQ
EGSRRLPIVSAKRQIGGTNLLPNRQSYLPLKLNAGGVMPIIFASALIFLPITIANFTKNPLLIRAASTLNPSAANPWPYA
LVFFALIVGFSYFYASLTINPIDIATNLKRGGVAIPGVRPGSATANYLSGVQNRLTLLGGLFLGAVAIIPAAVERATNVQ
TFQGLGATSLLILVGVAIDTAKQVQTYVISQRYEGLVRQ

Sequences:

>Translated_439_residues
MFVSRGRNPSAAEVISQLVRNPELRGRVLTTLGLLLFIRLGIYIPMPGIDRVAFQSFLQQGGQLIGFLDIFTGGGISTLG
IFALGILPFINASIILQLLTAALPQLEDLQKNEGEAGRRKIAQITRYVALGWGLVQSVIFALILRQYAVEGLSEVVFVVQ
TALALVTGSMIVMWMSEIITDRGIGQGASLVIFLNIVATLPKALASTIEKAQTGDRGDVVGIIVLVMVFLMTIVGIIFVQ
EGSRRLPIVSAKRQIGGTNLLPNRQSYLPLKLNAGGVMPIIFASALIFLPITIANFTKNPLLIRAASTLNPSAANPWPYA
LVFFALIVGFSYFYASLTINPIDIATNLKRGGVAIPGVRPGSATANYLSGVQNRLTLLGGLFLGAVAIIPAAVERATNVQ
TFQGLGATSLLILVGVAIDTAKQVQTYVISQRYEGLVRQ
>Mature_439_residues
MFVSRGRNPSAAEVISQLVRNPELRGRVLTTLGLLLFIRLGIYIPMPGIDRVAFQSFLQQGGQLIGFLDIFTGGGISTLG
IFALGILPFINASIILQLLTAALPQLEDLQKNEGEAGRRKIAQITRYVALGWGLVQSVIFALILRQYAVEGLSEVVFVVQ
TALALVTGSMIVMWMSEIITDRGIGQGASLVIFLNIVATLPKALASTIEKAQTGDRGDVVGIIVLVMVFLMTIVGIIFVQ
EGSRRLPIVSAKRQIGGTNLLPNRQSYLPLKLNAGGVMPIIFASALIFLPITIANFTKNPLLIRAASTLNPSAANPWPYA
LVFFALIVGFSYFYASLTINPIDIATNLKRGGVAIPGVRPGSATANYLSGVQNRLTLLGGLFLGAVAIIPAAVERATNVQ
TFQGLGATSLLILVGVAIDTAKQVQTYVISQRYEGLVRQ

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=426, Percent_Identity=40.8450704225352, Blast_Score=259, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 46972; Mature: 46972

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00755 SECY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1420358 [H]