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The map label for this gene is ho1 [H]

Identifier: 33863952

GI number: 33863952

Start: 1788410

End: 1789129

Strand: Direct

Name: ho1 [H]

Synonym: PMT1685

Alternate gene names: 33863952

Gene position: 1788410-1789129 (Clockwise)

Preceding gene: 33863951

Following gene: 33863953

Centisome position: 74.18

GC content: 53.75

Gene sequence:

>720_bases
TTGGCGGTAGCCCTTGCGAGCCAACTAAGAGAAGGCACCAAGGCCGCCCACACGATGGCCGAGAACACTGGTTTCGTGAG
CTGTTTCCTTAAAGGGGTGGTTGATCAGTCCAGTTATCGCATGCTGGTGGCTGATCTCTATTTCGTCTACTCCGCACTGG
AAGCAGAAATCGGCAAGCTGCGTGAGCAAAAGCATCCGGTGGTGGCACCTATTGGCTTCCCCGAGCTCAATCGCTGCGAG
GCCTTAGAACAAGATTTGATTTTTTATTTCGGCAGCGACTGGCGCAATCTGGCCAAGGCGACGCTGGCGGCTCAGGAGTA
TGTGGCCCGTATTCATAAGTTGGCGCAGGAGTCGCCTGAGTTACTAGTGGCTCATCACTACACCCGCTATCTTGGGGACC
TTTCAGGCGGTCAGATTCTCAAGACCATTGCCCAGAAGGCCATGAAGCTAGGGGGCAATGACGGCGTGCGTTTTTATATC
TTTAATGACATTGAAGACACCAAAGCGTTCAAGACTCTATACAGCGCCACCCTTGACAGCCTGCCGATCAATCAGCAAAC
CGCCGAACGCATGGTCGAGGAGGCAAATATGGCCTTTCACTGCAATATGGCCATGTTCAAGGAGTTGGAAGGCAACCTAG
TGGCTGCAATTGGAAAGGTCCTGTTTGGATTCCTCACGAGCCGCCAACGAGGCGGCAGCACTGAGGATGCGGTGGCCTAA

Upstream 100 bases:

>100_bases
GCCGTTGCATCCTGTTCAAGTACGAATCCTTCTTTTAAGGTCTTCCTAAAACTGCCATTTAGCCTCCTAGGGTCAATCAA
GACATTCGACTTCAAGCACC

Downstream 100 bases:

>100_bases
GAGGAAAAAGCAAGAGGTTGGCGGAGAATTAACACCTTCAACTGTTCAACACTTTCAACCTGGCTGAGGATGAAATGCTT
GCGATCACCAGTCTCTATCA

Product: Heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKLREQKHPVVAPIGFPELNRCE
ALEQDLIFYFGSDWRNLAKATLAAQEYVARIHKLAQESPELLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYI
FNDIEDTKAFKTLYSATLDSLPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA

Sequences:

>Translated_239_residues
MAVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKLREQKHPVVAPIGFPELNRCE
ALEQDLIFYFGSDWRNLAKATLAAQEYVARIHKLAQESPELLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYI
FNDIEDTKAFKTLYSATLDSLPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA
>Mature_238_residues
AVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKLREQKHPVVAPIGFPELNRCEA
LEQDLIFYFGSDWRNLAKATLAAQEYVARIHKLAQESPELLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYIF
NDIEDTKAFKTLYSATLDSLPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae [H]

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI187761311, Length=208, Percent_Identity=50, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI187761309, Length=208, Percent_Identity=50, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI187761307, Length=208, Percent_Identity=50, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI8051608, Length=208, Percent_Identity=50, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI4504437, Length=212, Percent_Identity=46.2264150943396, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 26471; Mature: 26339

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00593 HEME_OXYGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKL
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
REQKHPVVAPIGFPELNRCEALEQDLIFYFGSDWRNLAKATLAAQEYVARIHKLAQESPE
HHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
LLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYIFNDIEDTKAFKTLYSATLDS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
LPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA
CCCCHHHHHHHHHHCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKL
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
REQKHPVVAPIGFPELNRCEALEQDLIFYFGSDWRNLAKATLAAQEYVARIHKLAQESPE
HHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
LLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYIFNDIEDTKAFKTLYSATLDS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
LPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA
CCCCHHHHHHHHHHCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]