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The map label for this gene is hflX [H]

Identifier: 33863893

GI number: 33863893

Start: 1727169

End: 1728845

Strand: Direct

Name: hflX [H]

Synonym: PMT1626

Alternate gene names: 33863893

Gene position: 1727169-1728845 (Clockwise)

Preceding gene: 33863892

Following gene: 33863894

Centisome position: 71.64

GC content: 55.4

Gene sequence:

>1677_bases
TTGAAACAAGCCCACCTCGCTGGCCGCACCAAGGGACTACGCCCTTCACAACAAAGACAATTAGAACGCCTCAGCCACCG
CCGGCATCCCGAAAGGGAAGGCGCCGATCAGCTAACTCTAGAACGGCTAGCTGAAAAGGTGATTGAGCTATGCCAACCAC
TCCATTTAGTGCTGGATAGCCGTGGATTGTGCCGCCTTCTTTGGGTCGGTCCTCTCGATGGATCCGGCCAACTTCTCGCC
CATCTTCCTGAATCACCCCGTCGCAAGAGCGCTGGATGGCGCTTAATCAGCTGCTCTCTAACGCTTCAGCGAAACAACCT
CAGGCCAGAACAACATGATGCAATCGTGGCACTCGATCTAGCACCGAACTCCTGGCTACGTTTTGCCCCCACATCAGATC
GAGGAGGTCGCAGGATTGCGGCCCTCTGGCAACCAGATCCAAAGGAGATCTCGGGATGGAGCTTGATCGAAGCCAACGGA
CTAAGCGAGCTCTGCCAACACAGCCAAGGATCAACCGTCAAGCCAGAAGTCACCCCCCTACCGTCAAAGGACAGTAGGGA
ACGGGTCCTACTACTGACCCTTACGGGACCAGAGCAAAGCCGCAGCGAACGCGACCTTGCTGAGCTCGAGGGGTTGGTAC
GCAGTGCAGGGGGGCATCCTGTAGCAGTTGTGCGACAAAAGCAGGGGGCGCCTAATCCTCAGACCCTCTGGGGCAAGGGG
AAACTACAAGAGACCGCCTTGGAAGTTCGGCGTCATAGCGCTTCTCTAGTGATCACAGACCGTGAGCTCAATCCTGTTCA
AGTCAGGAATCTGGAGCGCTATCTCGACTGCCCTGTCATGGATCGCAGTGAATTAATCCTAGACATCTTTGCCCAGCGCG
CCTCTAGTGCAGCAGGCCGCCTTCAAGTGGAACTAGCCCAACTTCGCTATCGCATGCCAAGGCTAATGGGGCGAGGTCGC
AGCCTATCCCGTCAGGGAGGTGGCATCGGCACACGCGGGCCCGGCGAGACCCAACTCGAGAAAGACCGGCGTGCGATTAC
ACGACGCATCGAGCACTTGTTACGTGAGGTACGGCAACTGCAAAACCATCGCGCCCGACTACGAAACCGCAGGGAAGGTC
TACCAAGGGTTGCACTCGTGGGTTATACCAATGCGGGGAAATCATCCCTACTCAATGCTCTCTGCAGTCGAAACGAGCAC
AACAAAGTGCTGGCAGAGAACAAACTGTTTGCAACCTTGGATCCAACCACCCGACGATTGTTGATTCCTCAGACAGGTGG
AAAACCCCTTGAGCTTCTTATCACAGACACTGTGGGCTTCATCCGTGAACTGCCAGCGCCATTAGTGGAAGCCTTTCGGG
CCACTCTGGAGGAAACTCTTGAAGCCGATCTCCTCCTAGTGGTTGTGGACTTGTCAGACACAGACTGGCAAGCCCAACTG
GACACAGTGCATCAGTTGCTTAATTCCCTTGGCTCAGAATCAATCCGGCAGGTGATAGCCAATCAAATTGATCGCTGTGA
TAGCAGTGCACTTGAGACAATCCGCAGCATCGACCCGAAGGTGATTTATCTCTCCGCGGCCTCAGGTGCCGGGCTGCAAG
GACTCAAACACTGGCTGAAGGACCAATTCTGGGGTCACAGAGCAGAATCGGCCCCTCTGCATTCTGTAAATACCTAA

Upstream 100 bases:

>100_bases
CAGGTCCTCTGGCTTTCCAAATTCGCCGGGGTGCCTATCTAACAAAACTACCTGGATTGTCTCTAGGCCTGCGCTCAGGC
GGGGCCTGGCTGCTCGGACA

Downstream 100 bases:

>100_bases
CTATGGCTGTGCTGAGCACCGCTATTCAAAACCCCCAAGCCCTCATCACCCTGGCGGTGTTGTTGCTGGCGGTGGTGCTC
TTCATCAGCGGTGCCCTTGC

Product: GTP-binding protein, transport associated

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEKVIELCQPLHLVLDSRGLCRLLWVGPLDGSGQLLA
HLPESPRRKSAGWRLISCSLTLQRNNLRPEQHDAIVALDLAPNSWLRFAPTSDRGGRRIAALWQPDPKEISGWSLIEANG
LSELCQHSQGSTVKPEVTPLPSKDSRERVLLLTLTGPEQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
KLQETALEVRRHSASLVITDRELNPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGRLQVELAQLRYRMPRLMGRGR
SLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQLQNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEH
NKVLAENKLFATLDPTTRRLLIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
DTVHQLLNSLGSESIRQVIANQIDRCDSSALETIRSIDPKVIYLSAASGAGLQGLKHWLKDQFWGHRAESAPLHSVNT

Sequences:

>Translated_558_residues
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEKVIELCQPLHLVLDSRGLCRLLWVGPLDGSGQLLA
HLPESPRRKSAGWRLISCSLTLQRNNLRPEQHDAIVALDLAPNSWLRFAPTSDRGGRRIAALWQPDPKEISGWSLIEANG
LSELCQHSQGSTVKPEVTPLPSKDSRERVLLLTLTGPEQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
KLQETALEVRRHSASLVITDRELNPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGRLQVELAQLRYRMPRLMGRGR
SLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQLQNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEH
NKVLAENKLFATLDPTTRRLLIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
DTVHQLLNSLGSESIRQVIANQIDRCDSSALETIRSIDPKVIYLSAASGAGLQGLKHWLKDQFWGHRAESAPLHSVNT
>Mature_558_residues
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEKVIELCQPLHLVLDSRGLCRLLWVGPLDGSGQLLA
HLPESPRRKSAGWRLISCSLTLQRNNLRPEQHDAIVALDLAPNSWLRFAPTSDRGGRRIAALWQPDPKEISGWSLIEANG
LSELCQHSQGSTVKPEVTPLPSKDSRERVLLLTLTGPEQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
KLQETALEVRRHSASLVITDRELNPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGRLQVELAQLRYRMPRLMGRGR
SLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQLQNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEH
NKVLAENKLFATLDPTTRRLLIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
DTVHQLLNSLGSESIRQVIANQIDRCDSSALETIRSIDPKVIYLSAASGAGLQGLKHWLKDQFWGHRAESAPLHSVNT

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=241, Percent_Identity=32.7800829875519, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI310133116, Length=220, Percent_Identity=32.7272727272727, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310124269, Length=215, Percent_Identity=32.093023255814, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI310124267, Length=215, Percent_Identity=32.093023255814, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI310124171, Length=215, Percent_Identity=32.093023255814, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI310124169, Length=215, Percent_Identity=32.093023255814, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1790615, Length=371, Percent_Identity=42.5876010781671, Blast_Score=251, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17561038, Length=318, Percent_Identity=29.874213836478, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24650079, Length=357, Percent_Identity=35.0140056022409, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 62334; Mature: 62334

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEKVIELCQPLHLVLDS
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGLCRLLWVGPLDGSGQLLAHLPESPRRKSAGWRLISCSLTLQRNNLRPEQHDAIVALDL
CCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEE
APNSWLRFAPTSDRGGRRIAALWQPDPKEISGWSLIEANGLSELCQHSQGSTVKPEVTPL
CCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCC
PSKDSRERVLLLTLTGPEQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
KLQETALEVRRHSASLVITDRELNPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGR
CHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
LQVELAQLRYRMPRLMGRGRSLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEHNKVLAENKLFATLDPTTRRL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCEE
LIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
EEECCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
DTVHQLLNSLGSESIRQVIANQIDRCDSSALETIRSIDPKVIYLSAASGAGLQGLKHWLK
HHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DQFWGHRAESAPLHSVNT
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEKVIELCQPLHLVLDS
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGLCRLLWVGPLDGSGQLLAHLPESPRRKSAGWRLISCSLTLQRNNLRPEQHDAIVALDL
CCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEE
APNSWLRFAPTSDRGGRRIAALWQPDPKEISGWSLIEANGLSELCQHSQGSTVKPEVTPL
CCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCC
PSKDSRERVLLLTLTGPEQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
KLQETALEVRRHSASLVITDRELNPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGR
CHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
LQVELAQLRYRMPRLMGRGRSLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEHNKVLAENKLFATLDPTTRRL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCEE
LIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
EEECCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
DTVHQLLNSLGSESIRQVIANQIDRCDSSALETIRSIDPKVIYLSAASGAGLQGLKHWLK
HHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DQFWGHRAESAPLHSVNT
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]