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The map label for this gene is msrB [H]

Identifier: 33863853

GI number: 33863853

Start: 1688024

End: 1688458

Strand: Reverse

Name: msrB [H]

Synonym: PMT1586

Alternate gene names: 33863853

Gene position: 1688458-1688024 (Counterclockwise)

Preceding gene: 33863854

Following gene: 33863849

Centisome position: 70.04

GC content: 54.25

Gene sequence:

>435_bases
ATGTCCAGGTCTGATTCCTCCGCTTCCGATTCAGTGGATTGGATCAAGCTCAGCCCAGAAGAGTGGCAGGCCAGGTTGAC
TCGTGAGCAGTATCAGGTTGCCCGTAAGGGGGGCACAGAGCGAGCATTTACAGGTGCTTATTGGAACCACAAGGCAGCAG
GGATGTATTGCTGTGTCTGTTGTGGAGCCCCACTCTTCAGCTCAGCGACAAAATTCGATTCAGGCACTGGTTGGCCGAGC
TTTTCGGATGGAGTCAAGGCAGGTGCGATTACCACCCATCGGGACACTAGTCATGGAATGGAGCGTACTGAGATCAACTG
TGCTCGTTGTGGGGCTCATCTGGGCCATGTCTTTAACGACGGACCAGCGCCTACAGGTCAGAGGTACTGCGTGAACAGCG
CTTCGCTTGATTTTTCCGAGGAGGCAGAGGTTTGA

Upstream 100 bases:

>100_bases
ACTGGTTCGGCAGGTGCGTCGTTTGCTGCCCAAAGCTCTCGGTGCTTTTTAGATTCGAAGGCTGTTTAGGGTCTGGCAGG
TCCTCTTTCTTTTCCCTTCC

Downstream 100 bases:

>100_bases
TTTGAATCGAAGGTCACCAAGGGTCGTCCAGTTCGGTGCCATTACGGCGCTGTGGGGTCTCCTCTATCTCTGTATCTCGG
TCTCGGCCAGCTTGATCGCG

Product: methionine sulfoxide reductase family protein

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVCCGAPLFSSATKFDSGTGWPS
FSDGVKAGAITTHRDTSHGMERTEINCARCGAHLGHVFNDGPAPTGQRYCVNSASLDFSEEAEV

Sequences:

>Translated_144_residues
MSRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVCCGAPLFSSATKFDSGTGWPS
FSDGVKAGAITTHRDTSHGMERTEINCARCGAHLGHVFNDGPAPTGQRYCVNSASLDFSEEAEV
>Mature_143_residues
SRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVCCGAPLFSSATKFDSGTGWPSF
SDGVKAGAITTHRDTSHGMERTEINCARCGAHLGHVFNDGPAPTGQRYCVNSASLDFSEEAEV

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=56.8, Blast_Score=159, Evalue=9e-40,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=56.8, Blast_Score=159, Evalue=9e-40,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=56.8, Blast_Score=159, Evalue=9e-40,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=56.8, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=53.4351145038168, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI7706511, Length=94, Percent_Identity=37.2340425531915, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1788077, Length=125, Percent_Identity=54.4, Blast_Score=143, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=123, Percent_Identity=51.219512195122, Blast_Score=129, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=123, Percent_Identity=51.219512195122, Blast_Score=128, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=47.244094488189, Blast_Score=114, Evalue=8e-27,
Organism=Drosophila melanogaster, GI221378664, Length=129, Percent_Identity=53.4883720930233, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI221378662, Length=136, Percent_Identity=50.7352941176471, Blast_Score=152, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24645799, Length=127, Percent_Identity=53.5433070866142, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45553335, Length=127, Percent_Identity=53.5433070866142, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21356369, Length=127, Percent_Identity=53.5433070866142, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24645801, Length=138, Percent_Identity=50, Blast_Score=146, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24645804, Length=138, Percent_Identity=50, Blast_Score=146, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15623; Mature: 15492

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVC
CCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEHHH
CGAPLFSSATKFDSGTGWPSFSDGVKAGAITTHRDTSHGMERTEINCARCGAHLGHVFND
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GPAPTGQRYCVNSASLDFSEEAEV
CCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVC
CCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEHHH
CGAPLFSSATKFDSGTGWPSFSDGVKAGAITTHRDTSHGMERTEINCARCGAHLGHVFND
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GPAPTGQRYCVNSASLDFSEEAEV
CCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA