BacMap

Definition	Prochlorococcus marinus str. MIT 9313 chromosome, complete genome.
Accession	NC_005071
Length	2,410,873

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The map label for this gene is cyp [H]

Identifier: 33863832

GI number: 33863832

Start: 1661568

End: 1662866

Strand: Direct

Name: cyp [H]

Synonym: PMT1565

Alternate gene names: 33863832

Gene position: 1661568-1662866 (Clockwise)

Preceding gene: 33863831

Following gene: 33863833

Centisome position: 68.92

GC content: 54.66

Gene sequence:

>1299_bases
ATGGCGAGTTCTGATGATGCCAAGCTTCGCCCTCTTCCCAATACAGCGGCCCTGAGTGGGGTACTTGAAGCGTTTGCATT
TTTTCGCGATCCAGCCTTTGCACAGAAGCGCTTTGAGCGTCACGGGAATGTTTTTGAAACATCACTGCTCGGACAGCCAA
TGGTGTTCATTCAGGGCGGGCAAGCGATTCGTGATCTGCTCGCTCAACCCAACGCAGTAGAAGGTTGGTGGCCAGAGAGT
GTGCGGCAGCTGTTGGGCAGCCATTCGCTGGCTAACCGCAACGGAGCCTCCCATCGAGCACGCCGAAGAGTGATAGGCCA
ACTGTTCTCGGCCTCAGCACTACAACGCTACAGCGCTGGCATCATCAGCATGGTTCAAGATCTTGCCGACGAACTACAAG
CTGCAAAAACAGCTCTGCCTCTCGCAGAGAGAATGCGTCGTTTCGCTTTCTCGGTGATCGCCACGACGGTTCTCGGATTG
GAGGGTACTGATCGCGATGAGTTGTTCGTTGATTTCGAGATCTGGACCAGAGCCCTCTTCTCAATACCGATAGCTCTTCC
AGGTAGCTCCTTTGCCAAAGCGCTTAAGGCACGGGAACGGTTGTTGAGGAGGCTTCAGAAAGTGCTTTTAAAAGCATCCA
ATGGCAACGGTGGTCTTGATCTGCTTGCGGGAGGTCTCGATGAAGCAGGTATTCCTTTAACGGACGAAGACATGGTAGAG
CAGCTTCTGCTTCTTCTGTTCGCAGGCTACGAGACCACGGCTTCTTCGCTCAGCTGTCTGATGCGGGAGCTCCTTCTCAA
CCCGCAAGTGGAAACCTGGCTGCGAGAGGAAATCAATGGAGTTGACTGGCCTCCAGCACCCGAGCAGGCCACCACTGCCT
ACGACCAGGTAAACGCACCAAAACTGGACGCTGTCGTTTCTGAGGTCATGCGACTCACGCCAGCGGTGGGAGGGTTTTTT
CGCCGCACGAAATGCGCCTTGGTAATCGACGGTGTGGAGGTGCCAAAAAACCGTGTGGTACAGGTTGCTCTGGCAGCTTC
TAACCGTCATGGTGCTGGCGATCTGGAAGCCTTTCGTCCCCAGCGCCACCTAGAGGATGGCTGTTCAGCAACCCTGCTGC
CTTTTGGGGGGGGAGAGCGAGTATGCCTAGGCAAACCACTAGCGGAACTTGAAATACGTTTGATGGTGGTCGGCTTGTTT
CACCAGTTGCGACTTCACTTGATCCCTGATCAAGACCTCACTCTGCAAATGCTGCCTAGCCCTACACCCCGAGATGGCCT
GCTAACGAAAGTGCTGTAA

Upstream 100 bases:

>100_bases
TAGAAACGTATTAAGCCCCTTATTTCCTTCAGGGTGTTTCGTCAATTCTTCAAGGTTTGCTCTATCGCCCCATTAGCTTT
GCTGTTGGATAGAAAATGTC

Downstream 100 bases:

>100_bases
AAAACTCCAAAGTTGTTCTTGGTTTTGCTGCTGCTTTGCTGAAGATAGTTAAATCCATCAAAACTGAGCAAAAAACTTAT
GCAACCAACAACCTTGCTTC

Product: cytochrome P450 enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MASSDDAKLRPLPNTAALSGVLEAFAFFRDPAFAQKRFERHGNVFETSLLGQPMVFIQGGQAIRDLLAQPNAVEGWWPES
VRQLLGSHSLANRNGASHRARRRVIGQLFSASALQRYSAGIISMVQDLADELQAAKTALPLAERMRRFAFSVIATTVLGL
EGTDRDELFVDFEIWTRALFSIPIALPGSSFAKALKARERLLRRLQKVLLKASNGNGGLDLLAGGLDEAGIPLTDEDMVE
QLLLLLFAGYETTASSLSCLMRELLLNPQVETWLREEINGVDWPPAPEQATTAYDQVNAPKLDAVVSEVMRLTPAVGGFF
RRTKCALVIDGVEVPKNRVVQVALAASNRHGAGDLEAFRPQRHLEDGCSATLLPFGGGERVCLGKPLAELEIRLMVVGLF
HQLRLHLIPDQDLTLQMLPSPTPRDGLLTKVL

Sequences:

>Translated_432_residues
MASSDDAKLRPLPNTAALSGVLEAFAFFRDPAFAQKRFERHGNVFETSLLGQPMVFIQGGQAIRDLLAQPNAVEGWWPES
VRQLLGSHSLANRNGASHRARRRVIGQLFSASALQRYSAGIISMVQDLADELQAAKTALPLAERMRRFAFSVIATTVLGL
EGTDRDELFVDFEIWTRALFSIPIALPGSSFAKALKARERLLRRLQKVLLKASNGNGGLDLLAGGLDEAGIPLTDEDMVE
QLLLLLFAGYETTASSLSCLMRELLLNPQVETWLREEINGVDWPPAPEQATTAYDQVNAPKLDAVVSEVMRLTPAVGGFF
RRTKCALVIDGVEVPKNRVVQVALAASNRHGAGDLEAFRPQRHLEDGCSATLLPFGGGERVCLGKPLAELEIRLMVVGLF
HQLRLHLIPDQDLTLQMLPSPTPRDGLLTKVL
>Mature_431_residues
ASSDDAKLRPLPNTAALSGVLEAFAFFRDPAFAQKRFERHGNVFETSLLGQPMVFIQGGQAIRDLLAQPNAVEGWWPESV
RQLLGSHSLANRNGASHRARRRVIGQLFSASALQRYSAGIISMVQDLADELQAAKTALPLAERMRRFAFSVIATTVLGLE
GTDRDELFVDFEIWTRALFSIPIALPGSSFAKALKARERLLRRLQKVLLKASNGNGGLDLLAGGLDEAGIPLTDEDMVEQ
LLLLLFAGYETTASSLSCLMRELLLNPQVETWLREEINGVDWPPAPEQATTAYDQVNAPKLDAVVSEVMRLTPAVGGFFR
RTKCALVIDGVEVPKNRVVQVALAASNRHGAGDLEAFRPQRHLEDGCSATLLPFGGGERVCLGKPLAELEIRLMVVGLFH
QLRLHLIPDQDLTLQMLPSPTPRDGLLTKVL

Specific function: Unknown

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI9845285, Length=420, Percent_Identity=30.7142857142857, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI62952502, Length=475, Percent_Identity=30.1052631578947, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI16933530, Length=423, Percent_Identity=30.0236406619385, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI16933528, Length=416, Percent_Identity=30.0480769230769, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI16933533, Length=208, Percent_Identity=31.25, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI12383060, Length=209, Percent_Identity=30.622009569378, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI13435386, Length=197, Percent_Identity=31.9796954314721, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4503231, Length=196, Percent_Identity=30.6122448979592, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI195972896, Length=210, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI195972898, Length=210, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI261278370, Length=210, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI261278372, Length=210, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4503213, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI310125128, Length=183, Percent_Identity=34.9726775956284, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI14550409, Length=183, Percent_Identity=34.9726775956284, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI310125130, Length=183, Percent_Identity=34.9726775956284, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI190570174, Length=183, Percent_Identity=34.9726775956284, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI55770850, Length=196, Percent_Identity=32.6530612244898, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI262290932, Length=192, Percent_Identity=29.6875, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4503211, Length=176, Percent_Identity=32.3863636363636, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI45267826, Length=219, Percent_Identity=27.8538812785388, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI34098959, Length=342, Percent_Identity=23.9766081871345, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI62952506, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI16933535, Length=133, Percent_Identity=36.0902255639098, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI5729796, Length=372, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI29837648, Length=217, Percent_Identity=25.3456221198157, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI167466231, Length=212, Percent_Identity=31.1320754716981, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI158937242, Length=198, Percent_Identity=29.2929292929293, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI119220562, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI13435391, Length=200, Percent_Identity=27.5, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI153218662, Length=201, Percent_Identity=25.8706467661692, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI153218660, Length=201, Percent_Identity=25.8706467661692, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI6005737, Length=200, Percent_Identity=27, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982956, Length=419, Percent_Identity=24.8210023866348, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982977, Length=367, Percent_Identity=25.3405994550409, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115532670, Length=363, Percent_Identity=25.6198347107438, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI212646200, Length=193, Percent_Identity=27.979274611399, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536179, Length=220, Percent_Identity=26.3636363636364, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17552522, Length=356, Percent_Identity=23.876404494382, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540354, Length=204, Percent_Identity=29.9019607843137, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564386, Length=179, Percent_Identity=29.608938547486, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17536175, Length=209, Percent_Identity=30.1435406698565, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536177, Length=209, Percent_Identity=30.1435406698565, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71998720, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536191, Length=201, Percent_Identity=28.8557213930348, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72001056, Length=247, Percent_Identity=24.6963562753036, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17557258, Length=207, Percent_Identity=29.951690821256, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557254, Length=179, Percent_Identity=30.7262569832402, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564172, Length=168, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536187, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17564242, Length=163, Percent_Identity=32.5153374233129, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536183, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24656064, Length=417, Percent_Identity=23.9808153477218, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571357, Length=434, Percent_Identity=24.8847926267281, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24642101, Length=435, Percent_Identity=23.6781609195402, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582534, Length=427, Percent_Identity=22.7166276346604, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221330401, Length=189, Percent_Identity=30.6878306878307, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21357069, Length=404, Percent_Identity=24.5049504950495, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45553345, Length=404, Percent_Identity=24.5049504950495, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358207, Length=372, Percent_Identity=25.5376344086022, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641483, Length=351, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19921824, Length=385, Percent_Identity=23.8961038961039, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19921686, Length=380, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653207, Length=379, Percent_Identity=26.3852242744063, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552577, Length=207, Percent_Identity=27.536231884058, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24943083, Length=207, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18079270, Length=218, Percent_Identity=29.8165137614679, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21358007, Length=334, Percent_Identity=22.4550898203593, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17864130, Length=220, Percent_Identity=25.4545454545455, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR017972
- InterPro:   IPR002401 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 47298; Mature: 47167

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSDDAKLRPLPNTAALSGVLEAFAFFRDPAFAQKRFERHGNVFETSLLGQPMVFIQGG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEHHHCCCCEEEEECC
QAIRDLLAQPNAVEGWWPESVRQLLGSHSLANRNGASHRARRRVIGQLFSASALQRYSAG
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IISMVQDLADELQAAKTALPLAERMRRFAFSVIATTVLGLEGTDRDELFVDFEIWTRALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
SIPIALPGSSFAKALKARERLLRRLQKVLLKASNGNGGLDLLAGGLDEAGIPLTDEDMVE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHHH
QLLLLLFAGYETTASSLSCLMRELLLNPQVETWLREEINGVDWPPAPEQATTAYDQVNAP
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
KLDAVVSEVMRLTPAVGGFFRRTKCALVIDGVEVPKNRVVQVALAASNRHGAGDLEAFRP
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHCC
QRHLEDGCSATLLPFGGGERVCLGKPLAELEIRLMVVGLFHQLRLHLIPDQDLTLQMLPS
HHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
PTPRDGLLTKVL
CCCCCCCHHHCC
>Mature Secondary Structure 
ASSDDAKLRPLPNTAALSGVLEAFAFFRDPAFAQKRFERHGNVFETSLLGQPMVFIQGG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEHHHCCCCEEEEECC
QAIRDLLAQPNAVEGWWPESVRQLLGSHSLANRNGASHRARRRVIGQLFSASALQRYSAG
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IISMVQDLADELQAAKTALPLAERMRRFAFSVIATTVLGLEGTDRDELFVDFEIWTRALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
SIPIALPGSSFAKALKARERLLRRLQKVLLKASNGNGGLDLLAGGLDEAGIPLTDEDMVE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHHH
QLLLLLFAGYETTASSLSCLMRELLLNPQVETWLREEINGVDWPPAPEQATTAYDQVNAP
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
KLDAVVSEVMRLTPAVGGFFRRTKCALVIDGVEVPKNRVVQVALAASNRHGAGDLEAFRP
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHCC
QRHLEDGCSATLLPFGGGERVCLGKPLAELEIRLMVVGLFHQLRLHLIPDQDLTLQMLPS
HHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
PTPRDGLLTKVL
CCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]