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The map label for this gene is obgE [H]

Identifier: 33863811

GI number: 33863811

Start: 1634445

End: 1635434

Strand: Reverse

Name: obgE [H]

Synonym: PMT1544

Alternate gene names: 33863811

Gene position: 1635434-1634445 (Counterclockwise)

Preceding gene: 33863813

Following gene: 33863810

Centisome position: 67.84

GC content: 53.84

Gene sequence:

>990_bases
GTGCAGTTCATAGATCAGGCACGTATCACCGTTAGAGCCGGTCGCGGTGGCGATGGGATCATGGCTTTTAGGCGGGAGAA
GTATGTGCCGGCTGGCGGTCCCTCTGGTGGGGATGGCGGTAATGGCGGCAACGTCGTTCTTGAAGCGGATGGCAACCTTC
AGACCCTGCTGGATTTTAAGTACAAGAGACTTTTCCCAGCGCCTGATGGTCGGCGGGGTGGTCCGAATCGCTGTACCGGC
GCTTCAGGTAAAGACTTGATCATCAAGGTGCCATGTGGCACTGAAGTGCGTCATCTCTACACGGGCATCCTTCTGGGTGA
CCTCACTCGATCTGAAGATCTACTTGTGGTGGCTTTTGGAGGGCGTGGAGGGCTTGGTAATGCCCATTACCTCAGTAATC
GAAACCGTGCTCCTGAGAAATTCACGGAAGGGCGCGATGGGGAGGAATGGTTCCTTCAATTGGAACTCAAGTTATTAGCA
GAGGTGGGGATCATTGGTTTGCCGAATGCAGGCAAGAGCACTTTGATTTCTGTGCTTTCGGCAGCCCGGCCCAAGATTGC
TGATTATCCCTTCACCACATTGGTGCCTAATCTCGGTGTGGTGCGTCGACCCAGCGGAGATGGCACAGTTTTCGCTGATA
TCCCTGGTCTGATTGCCGGTGCAGCACAAGGAGCAGGCCTAGGGCATGATTTCCTTCGCCACATCGAACGCACCAGGCTG
TTGATTCATGTGTTGGATGGTGGCGCAGAAGATCCAGTTGAAGACTTGCTGGTGGTTGAAAAGGAGCTGGTTGCTTATGG
CCATGACTTGGTTGAAAGGCCACGGCTGTTGGTGCTCAATAAACAGGAGTTATTGGATGAACAGCATCAAGATCAGCTGG
TTGATGCCCTTCAGGCAGCGAGTGGTCGAAGCTTGATTTTGATTTCTGCGGCCATGGGTCTAGGCCTTGAGGGGCTGTTG
GCGCAGGTATGGAAGGAACTTGGCGTCTGA

Upstream 100 bases:

>100_bases
GGTAGCTCTTGTTGAGAGCCTTGAAGCGAACGCCGGCCACTCACAGTTCCCCGATCAAGCTGATCCTAGGGTTGGAGCTT
GGCCAAGCTGGGCGCTTGCA

Downstream 100 bases:

>100_bases
GGTTTTCAGGTCTGCCAGACCATATCCAGACTTGTGTGTTCGCGGGTCATTGGTCATAACTGGAGTGAAACCATTGATGT
CATGACCTTTTACAGCTGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQFIDQARITVRAGRGGDGIMAFRREKYVPAGGPSGGDGGNGGNVVLEADGNLQTLLDFKYKRLFPAPDGRRGGPNRCTG
ASGKDLIIKVPCGTEVRHLYTGILLGDLTRSEDLLVVAFGGRGGLGNAHYLSNRNRAPEKFTEGRDGEEWFLQLELKLLA
EVGIIGLPNAGKSTLISVLSAARPKIADYPFTTLVPNLGVVRRPSGDGTVFADIPGLIAGAAQGAGLGHDFLRHIERTRL
LIHVLDGGAEDPVEDLLVVEKELVAYGHDLVERPRLLVLNKQELLDEQHQDQLVDALQAASGRSLILISAAMGLGLEGLL
AQVWKELGV

Sequences:

>Translated_329_residues
MQFIDQARITVRAGRGGDGIMAFRREKYVPAGGPSGGDGGNGGNVVLEADGNLQTLLDFKYKRLFPAPDGRRGGPNRCTG
ASGKDLIIKVPCGTEVRHLYTGILLGDLTRSEDLLVVAFGGRGGLGNAHYLSNRNRAPEKFTEGRDGEEWFLQLELKLLA
EVGIIGLPNAGKSTLISVLSAARPKIADYPFTTLVPNLGVVRRPSGDGTVFADIPGLIAGAAQGAGLGHDFLRHIERTRL
LIHVLDGGAEDPVEDLLVVEKELVAYGHDLVERPRLLVLNKQELLDEQHQDQLVDALQAASGRSLILISAAMGLGLEGLL
AQVWKELGV
>Mature_329_residues
MQFIDQARITVRAGRGGDGIMAFRREKYVPAGGPSGGDGGNGGNVVLEADGNLQTLLDFKYKRLFPAPDGRRGGPNRCTG
ASGKDLIIKVPCGTEVRHLYTGILLGDLTRSEDLLVVAFGGRGGLGNAHYLSNRNRAPEKFTEGRDGEEWFLQLELKLLA
EVGIIGLPNAGKSTLISVLSAARPKIADYPFTTLVPNLGVVRRPSGDGTVFADIPGLIAGAAQGAGLGHDFLRHIERTRL
LIHVLDGGAEDPVEDLLVVEKELVAYGHDLVERPRLLVLNKQELLDEQHQDQLVDALQAASGRSLILISAAMGLGLEGLL
AQVWKELGV

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=319, Percent_Identity=42.6332288401254, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI111955139, Length=352, Percent_Identity=35.2272727272727, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI111955063, Length=188, Percent_Identity=37.7659574468085, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI58761500, Length=137, Percent_Identity=29.9270072992701, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=51.5243902439024, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1787454, Length=139, Percent_Identity=35.2517985611511, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=36.4197530864198, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=328, Percent_Identity=28.3536585365854, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17509631, Length=158, Percent_Identity=32.2784810126582, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=125, Percent_Identity=32.8, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=173, Percent_Identity=41.0404624277457, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=125, Percent_Identity=36.8, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321773, Length=172, Percent_Identity=30.8139534883721, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=322, Percent_Identity=38.8198757763975, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24585318, Length=293, Percent_Identity=37.542662116041, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=33.59375, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=33.59375, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=33.59375, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356473, Length=114, Percent_Identity=36.8421052631579, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35159; Mature: 35159

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDQARITVRAGRGGDGIMAFRREKYVPAGGPSGGDGGNGGNVVLEADGNLQTLLDFK
CCCCCCCEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
YKRLFPAPDGRRGGPNRCTGASGKDLIIKVPCGTEVRHLYTGILLGDLTRSEDLLVVAFG
HHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEC
GRGGLGNAHYLSNRNRAPEKFTEGRDGEEWFLQLELKLLAEVGIIGLPNAGKSTLISVLS
CCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGVVRRPSGDGTVFADIPGLIAGAAQGAGLGHDFLRHIERTRL
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHE
LIHVLDGGAEDPVEDLLVVEKELVAYGHDLVERPRLLVLNKQELLDEQHQDQLVDALQAA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHC
SGRSLILISAAMGLGLEGLLAQVWKELGV
CCCEEEEEEEHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFIDQARITVRAGRGGDGIMAFRREKYVPAGGPSGGDGGNGGNVVLEADGNLQTLLDFK
CCCCCCCEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
YKRLFPAPDGRRGGPNRCTGASGKDLIIKVPCGTEVRHLYTGILLGDLTRSEDLLVVAFG
HHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEC
GRGGLGNAHYLSNRNRAPEKFTEGRDGEEWFLQLELKLLAEVGIIGLPNAGKSTLISVLS
CCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGVVRRPSGDGTVFADIPGLIAGAAQGAGLGHDFLRHIERTRL
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHE
LIHVLDGGAEDPVEDLLVVEKELVAYGHDLVERPRLLVLNKQELLDEQHQDQLVDALQAA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHC
SGRSLILISAAMGLGLEGLLAQVWKELGV
CCCEEEEEEEHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA