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The map label for this gene is atpA [H]

Identifier: 33863734

GI number: 33863734

Start: 1553023

End: 1554540

Strand: Reverse

Name: atpA [H]

Synonym: PMT1467

Alternate gene names: 33863734

Gene position: 1554540-1553023 (Counterclockwise)

Preceding gene: 33863735

Following gene: 33863733

Centisome position: 64.48

GC content: 52.77

Gene sequence:

>1518_bases
ATGGTTTCCATCCGCCCCGACGAGATCAGCGCGATTCTTAAGCAGCAGATCTCCGACTATGACAAGTCGGTTTCCGTCAG
CAACGTCGGCACTGTTCTGCAGATTGGTGACGGTATCGCTCGTGTCTATGGCCTTGAGCAGGTCATGGCTGGCGAACTGG
TGGAATTTGAGGATGGCACTGAAGGGATCGCCCTCAATTTGGAGGACGACAACGTTGGTGCGGTGTTGATGGGTGAGGGT
GTTGGTATTCAGGAAGGCAGTACCGTCAAAGCCACTGGCAAGATTGCCTCAGTGCCCGTCAGCGATGAGATGCTGGGCAG
AGTGGTGACTCCTTTGGGTCAACCGATGGATGGCAAAGGCGACATCCCCAGCACTGAGAGTCGCTTGATTGAGTCGATAG
CTCCAGGCATCATCAAACGTAAGTCGGTGCATGAGCCACTGCAGACAGGGATTACATCAATCGATTCGATGATTCCTATC
GGTAGGGGTCAGCGTGAGTTGATCATTGGTGACCGTCAGACAGGTAAGACTGCGATCGCAATCGACACGATCATCAACCA
GAAGGGAGAAGATGTTGTCTGTGTTTATGTAGCTGTCGGCCAGAAGGCTGCCTCTGTGGCCAACGTAGTTGAGGTGCTTC
GCGAGAAGGGCGCTCTCGATTACACCGTGATTGTGGCAGCTAGCGCTTCCGACCCAGCTGCTTTGCAGTACCTGGCTCCT
TACACGGGCGCAGCTATTGCTGAGTCGTTCATGTACAAGGGCAAGGCGACTTTGGTCATCTACGACGATCTAACTAAGCA
GGCCCAGGCCTATCGTCAGATGTCACTGCTGCTGCGTCGTCCTCCCGGTCGTGAAGCCTATCCAGGAGATGTCTTCTATC
TCCACAGCCGCCTTCTTGAGAGGGCAGCAAAGCTTTCTGATGCGATGGGTAGCGGTTCGATGACGGCACTGCCGATCATT
GAAACCCAAGCAGGAGACGTGTCGGCTTATATCCCTACCAATGTGATTTCAATCACGGATGGTCAGATTTTCTTGAGTTC
AGATCTTTTCAACTCAGGATTGCGTCCTGCCATCAACGTTGGCATTTCAGTGAGCCGGGTTGGTGGTGCTGCGCAAACCA
AAGCGATCAAAAAGATTGCCGGCACGTTGAAGCTTGAGTTGGCTCAGTTTGATGAATTGGCTGCTTTCTCTCAGTTCGCC
TCTGATTTAGATGAAGCAACTCAGAAGCAGTTGGGGCGTGGTAAGAGACTGCGTGAGCTGCTTAAGCAGCCTCAGTTTGC
ACCGCTGAATTTGGCTGAGCAGGTTGCGATCGTTTATGCAGGAGTGAAAGGCTTGATTGATGAGGTGCCTGAGGATCAGG
TCACTCAGTTTTCACGTGAATTGCGTGATTACCTCAAGACCAACAAGCCCGAGTACATCACCAAAGTTCAGACTGAGAAG
GTGCTCAACGAGGATGCTGAGACCATTCTCAAGGCCGCCATCAACGAGGTGAAGTCGTCGATGCTGGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
TGCTGGACAGGTTCGACGTCTTGGCCTGGCACTGGCCAAGGTGAGCTAGCTCCCTACCTTTTTCTCTTTCTCACCCTCTT
CCTCAACACCAACGCCTCCC

Downstream 100 bases:

>100_bases
CCCTGAAGGTAAACCCGGAGAACCCTATCCATGGCGAACCTCAAGGACATCCGCGACCGGATCGTTTCCGTTAAGAACAC
CAGAAAGATTACTGAGGCGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEG
VGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKGDIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDPAALQYLAP
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAMGSGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
VLNEDAETILKAAINEVKSSMLASA

Sequences:

>Translated_505_residues
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEG
VGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKGDIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDPAALQYLAP
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAMGSGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
VLNEDAETILKAAINEVKSSMLASA
>Mature_505_residues
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEG
VGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKGDIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDPAALQYLAP
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAMGSGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
VLNEDAETILKAAINEVKSSMLASA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=58.9285714285714, Blast_Score=591, Evalue=1e-169,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=58.9285714285714, Blast_Score=591, Evalue=1e-169,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=30.1324503311258, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI19913426, Length=342, Percent_Identity=29.8245614035088, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI32189394, Length=395, Percent_Identity=23.7974683544304, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=53.968253968254, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1790170, Length=418, Percent_Identity=25.1196172248804, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788251, Length=332, Percent_Identity=27.710843373494, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=492, Percent_Identity=59.1463414634146, Blast_Score=594, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71988080, Length=492, Percent_Identity=59.1463414634146, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71988074, Length=492, Percent_Identity=55.4878048780488, Blast_Score=548, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI17510931, Length=296, Percent_Identity=28.3783783783784, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=315, Percent_Identity=28.8888888888889, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=395, Percent_Identity=24.5569620253165, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71988068, Length=78, Percent_Identity=46.1538461538462, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=497, Percent_Identity=57.5452716297787, Blast_Score=575, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6319603, Length=348, Percent_Identity=29.8850574712644, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=423, Percent_Identity=26.241134751773, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=58.8118811881188, Blast_Score=595, Evalue=1e-170,
Organism=Drosophila melanogaster, GI281361666, Length=346, Percent_Identity=28.3236994219653, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646341, Length=346, Percent_Identity=28.3236994219653, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136796, Length=346, Percent_Identity=28.3236994219653, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24638766, Length=404, Percent_Identity=24.2574257425743, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28574560, Length=410, Percent_Identity=25.609756097561, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583988, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583986, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583984, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583992, Length=247, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54047; Mature: 54047

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGT
CCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEECCCHHHHHHHHHHHHHCCCEEECCCC
EGIALNLEDDNVGAVLMGEGVGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKG
CCEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHCCCCCCCCC
DIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPIGRGQRELIIGDRQTGKTAIA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
IDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDPAALQYLAP
EEHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHCC
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
CCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDAMGSGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VLNEDAETILKAAINEVKSSMLASA
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGT
CCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEECCCHHHHHHHHHHHHHCCCEEECCCC
EGIALNLEDDNVGAVLMGEGVGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKG
CCEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHCCCCCCCCC
DIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPIGRGQRELIIGDRQTGKTAIA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
IDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDPAALQYLAP
EEHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHCC
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
CCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDAMGSGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VLNEDAETILKAAINEVKSSMLASA
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA