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The map label for this gene is ctaD [H]

Identifier: 33863609

GI number: 33863609

Start: 1427499

End: 1429175

Strand: Direct

Name: ctaD [H]

Synonym: PMT1342

Alternate gene names: 33863609

Gene position: 1427499-1429175 (Clockwise)

Preceding gene: 33863608

Following gene: 33863610

Centisome position: 59.21

GC content: 52.18

Gene sequence:

>1677_bases
ATGACGGTTGCCATCTCCCCTCCTAGCAAAAAGCAATCAGATGGTCTTCAACCAACTGGCTGGTTGCGTTACTTCAGCTT
CAGCCTTGACCACAAGGTCATTGGTCTGCAGTACTTGGTTTGCGGATTCATCTTCTACCTAATCGGCGGAGTGCTTGGTG
GCGCCATCCGCATCGAACTCGCCAGCCCCATCGCCGACTTCATGGGCAGGGATGTCTACAACCAGGTGCTAACGCTGCAC
GGCACAGTGATGATATTCCTGTGGATCGTGCCGGTCGTGAACGGTGCCTTCGGCAACTATCTCATTCCGTTTTATGTGGG
AGCCCGTGATATGGCCTTCCCTCGACTCAATGCCGTGGCGTTCTGGATGATCCCTCCAGCTGGCCTGTTGCTGATCAGTA
GCTACTTCATTACCGGTGCTGCTCAATCCGGCTGGACGGCCTATCCACCGCTGAGTATCACCACCCCCGCCGCAGGACAG
ATCTTATGGATTCTCAGTGTGCTCTTGCTTGGCGGTAGCTCAATCTTTGGTGGCATCAACTTCATCGCCACCATCCTCAA
GCTGAGGCAGCCCGGACTGAAGCTAATGCAACTACCCATGTACTGCTGGGCGATGCTCGGCACAAGCATCCTGGTGGTGC
TCTCCACACCAGTACTAGCTGGAACACTGATCCTTTTAAGTTTCGACATCGTTGCCCATACAGGATTCTTCAACCCCAGC
CTGGGCGGAAACGCAGTCGTCTACCAACATCTTTTCTGGTTTTATTCCCACCCAGCGGTATACATCATGGTGCTGCCAGC
CTTCGGATTGGTCAGCGAAATCCTTCCTGTTCACTGCCGCAAACCACTTTTTGGCTACACCTCAATGGTGTATTCAATCA
TGACCATCGTGATCCTTGGCCTCGTGGTTTGGGCACATCACATGTTCACAAGTGGAACACCTCCTTGGATGCGCCTCTTT
TTCACCATTGCCACATCCTTCATTGCCGTACCTACAGGAATTAAGTTCTTCAATTGGCTGGCAACACTCTGGGGAGGGCG
CATCTCTCTAAACAGTGCTGTGCTTTTCTCTTGTGGCTTCATTGTCAACTTTGTGCTTGGCGGCATTACTGGCGTAGCAC
TTGCACAAGTTCCATTCGACATTCACGTGCATGATACCTACTTTGTTGTTGCCCATTTTCACTACATCGTCTATGGAGGT
TCGGTGTTTGTGATCTTTGCCTCTATTTATCACTGGTATCCAAAATTCACTGGGCGCATGCTCAATGAATCTCTCGGGCG
GTTTCATTTTTTTATCACTTTCATCGGCTTCAATCTTTGCTTTGCCCCACAGCATTGGCTAGGCCTCAACGGCATGCCCC
GCCGTGTGGCGGAATACGACCCGCAATTCACCGTAATCAATCAAATTAGCAGTGTTGGGGCCTTGCTAATGGCCATCAGC
ACGCTGCCCTTTCTCTGGAACGTCGTGCAGAGTGCATTGAGCGGCCCCATTGCCGGAGACAACCCCTGGAGGGCGCTTAC
TCCTGAATGGCTCACCAGCTCCCCACCACCAGTGGAAAACTGGAGCGGCAAAGCCCCTCTGGTAACAGAGCCCTATGGCT
ATGGCGTACCTGGGGAGGAACTCAACCTAGAAAAAACCAGCAACAGTGATAGTGATCTAGGGAGCAAAAGCCAATGA

Upstream 100 bases:

>100_bases
GTCCATACCACGGGAACATGCATACGAAAGTGATTGTCGAAGAGCCCGGTGACTACGACACCTGGTTCAGCAACAACGCC
AAAACAACGGTTTCAGAAGC

Downstream 100 bases:

>100_bases
CATCCCTTCCAACGATCGACCATGACTATGAGGAGCAGGCTGATCTAGCAGATGATCATGCTGAGCTTGGCGAGGAACAT
GCTGATCACCGCATGTTCGG

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MTVAISPPSKKQSDGLQPTGWLRYFSFSLDHKVIGLQYLVCGFIFYLIGGVLGGAIRIELASPIADFMGRDVYNQVLTLH
GTVMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAFWMIPPAGLLLISSYFITGAAQSGWTAYPPLSITTPAAGQ
ILWILSVLLLGGSSIFGGINFIATILKLRQPGLKLMQLPMYCWAMLGTSILVVLSTPVLAGTLILLSFDIVAHTGFFNPS
LGGNAVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHCRKPLFGYTSMVYSIMTIVILGLVVWAHHMFTSGTPPWMRLF
FTIATSFIAVPTGIKFFNWLATLWGGRISLNSAVLFSCGFIVNFVLGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGG
SVFVIFASIYHWYPKFTGRMLNESLGRFHFFITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFTVINQISSVGALLMAIS
TLPFLWNVVQSALSGPIAGDNPWRALTPEWLTSSPPPVENWSGKAPLVTEPYGYGVPGEELNLEKTSNSDSDLGSKSQ

Sequences:

>Translated_558_residues
MTVAISPPSKKQSDGLQPTGWLRYFSFSLDHKVIGLQYLVCGFIFYLIGGVLGGAIRIELASPIADFMGRDVYNQVLTLH
GTVMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAFWMIPPAGLLLISSYFITGAAQSGWTAYPPLSITTPAAGQ
ILWILSVLLLGGSSIFGGINFIATILKLRQPGLKLMQLPMYCWAMLGTSILVVLSTPVLAGTLILLSFDIVAHTGFFNPS
LGGNAVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHCRKPLFGYTSMVYSIMTIVILGLVVWAHHMFTSGTPPWMRLF
FTIATSFIAVPTGIKFFNWLATLWGGRISLNSAVLFSCGFIVNFVLGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGG
SVFVIFASIYHWYPKFTGRMLNESLGRFHFFITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFTVINQISSVGALLMAIS
TLPFLWNVVQSALSGPIAGDNPWRALTPEWLTSSPPPVENWSGKAPLVTEPYGYGVPGEELNLEKTSNSDSDLGSKSQ
>Mature_557_residues
TVAISPPSKKQSDGLQPTGWLRYFSFSLDHKVIGLQYLVCGFIFYLIGGVLGGAIRIELASPIADFMGRDVYNQVLTLHG
TVMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAFWMIPPAGLLLISSYFITGAAQSGWTAYPPLSITTPAAGQI
LWILSVLLLGGSSIFGGINFIATILKLRQPGLKLMQLPMYCWAMLGTSILVVLSTPVLAGTLILLSFDIVAHTGFFNPSL
GGNAVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHCRKPLFGYTSMVYSIMTIVILGLVVWAHHMFTSGTPPWMRLFF
TIATSFIAVPTGIKFFNWLATLWGGRISLNSAVLFSCGFIVNFVLGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGS
VFVIFASIYHWYPKFTGRMLNESLGRFHFFITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFTVINQISSVGALLMAIST
LPFLWNVVQSALSGPIAGDNPWRALTPEWLTSSPPPVENWSGKAPLVTEPYGYGVPGEELNLEKTSNSDSDLGSKSQ

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=500, Percent_Identity=44.2, Blast_Score=386, Evalue=1e-107,
Organism=Escherichia coli, GI1786634, Length=535, Percent_Identity=39.6261682242991, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6226519, Length=525, Percent_Identity=37.9047619047619, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=39.937106918239, Blast_Score=239, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=35.3658536585366, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61405; Mature: 61274

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAISPPSKKQSDGLQPTGWLRYFSFSLDHKVIGLQYLVCGFIFYLIGGVLGGAIRIEL
CEEEECCCCCCCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
ASPIADFMGRDVYNQVLTLHGTVMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEE
FWMIPPAGLLLISSYFITGAAQSGWTAYPPLSITTPAAGQILWILSVLLLGGSSIFGGIN
EEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHH
FIATILKLRQPGLKLMQLPMYCWAMLGTSILVVLSTPVLAGTLILLSFDIVAHTGFFNPS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCC
LGGNAVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHCRKPLFGYTSMVYSIMTIVILG
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVVWAHHMFTSGTPPWMRLFFTIATSFIAVPTGIKFFNWLATLWGGRISLNSAVLFSCGF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECHHHHHHHHH
IVNFVLGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGSVFVIFASIYHWYPKFTGRM
HHHHHHHHHHHHHHHHCCEEEEECCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LNESLGRFHFFITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFTVINQISSVGALLMAIS
HHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
TLPFLWNVVQSALSGPIAGDNPWRALTPEWLTSSPPPVENWSGKAPLVTEPYGYGVPGEE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCC
LNLEKTSNSDSDLGSKSQ
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVAISPPSKKQSDGLQPTGWLRYFSFSLDHKVIGLQYLVCGFIFYLIGGVLGGAIRIEL
EEEECCCCCCCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
ASPIADFMGRDVYNQVLTLHGTVMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEE
FWMIPPAGLLLISSYFITGAAQSGWTAYPPLSITTPAAGQILWILSVLLLGGSSIFGGIN
EEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHH
FIATILKLRQPGLKLMQLPMYCWAMLGTSILVVLSTPVLAGTLILLSFDIVAHTGFFNPS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCC
LGGNAVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHCRKPLFGYTSMVYSIMTIVILG
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVVWAHHMFTSGTPPWMRLFFTIATSFIAVPTGIKFFNWLATLWGGRISLNSAVLFSCGF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECHHHHHHHHH
IVNFVLGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGSVFVIFASIYHWYPKFTGRM
HHHHHHHHHHHHHHHHCCEEEEECCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LNESLGRFHFFITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFTVINQISSVGALLMAIS
HHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
TLPFLWNVVQSALSGPIAGDNPWRALTPEWLTSSPPPVENWSGKAPLVTEPYGYGVPGEE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCC
LNLEKTSNSDSDLGSKSQ
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]