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The map label for this gene is phhB

Identifier: 33863551

GI number: 33863551

Start: 1369601

End: 1369891

Strand: Direct

Name: phhB

Synonym: PMT1283

Alternate gene names: NA

Gene position: 1369601-1369891 (Clockwise)

Preceding gene: 33863550

Following gene: 33863552

Centisome position: 56.81

GC content: 54.3

Gene sequence:

>291_bases
ATGACGGCAACCCTGCTTACTGCTGAACAGCTCTCTTCCGTAGCTGAAAAGCTGCCGGGGTGGACCCTGGCGGATCAACG
GCTGCAAAGGCAATGGCGCTTTCGCAACTTTGTGGAAGCCTTCGGTTTTATGACCCGTGTGGCACTGCTAGCTGAAGCCA
TGAACCATCACCCGGAATGGAGCAACGTCTATGCCACTGTGACGATCGAGTTGACGACCCATGACGTCAACGGATTGAGC
GATCGTGATTTGAAGCTCGCCGAAGCAATCAATTTGCTTGAGCCTGGCTGA

Upstream 100 bases:

>100_bases
GGACAACATCAAATCACCCTTCAACCATTGCATCATTCGAGCAACACAACACAGTAACCATCACAGACAAGAATGACTCC
AAAGCTCACAACACAACCTC

Downstream 100 bases:

>100_bases
TCAAAACTCACTCAGGCGAAACTGCTGCCAGCATGGAATCAAAGAACGGCTGTGGTTCCGGCACCCTCCCGTTCCCCTGA
CGGCAAGCCCATGAACGACG

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD [H]

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MTATLLTAEQLSSVAEKLPGWTLADQRLQRQWRFRNFVEAFGFMTRVALLAEAMNHHPEWSNVYATVTIELTTHDVNGLS
DRDLKLAEAINLLEPG

Sequences:

>Translated_96_residues
MTATLLTAEQLSSVAEKLPGWTLADQRLQRQWRFRNFVEAFGFMTRVALLAEAMNHHPEWSNVYATVTIELTTHDVNGLS
DRDLKLAEAINLLEPG
>Mature_95_residues
TATLLTAEQLSSVAEKLPGWTLADQRLQRQWRFRNFVEAFGFMTRVALLAEAMNHHPEWSNVYATVTIELTTHDVNGLSD
RDLKLAEAINLLEPG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI134133240, Length=76, Percent_Identity=52.6315789473684, Blast_Score=87, Evalue=3e-18,
Organism=Homo sapiens, GI4557831, Length=92, Percent_Identity=47.8260869565217, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115533705, Length=84, Percent_Identity=55.952380952381, Blast_Score=95, Evalue=7e-21,
Organism=Drosophila melanogaster, GI45549100, Length=80, Percent_Identity=51.25, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001533 [H]

Pfam domain/function: PF01329 Pterin_4a [H]

EC number: =4.2.1.96 [H]

Molecular weight: Translated: 10868; Mature: 10737

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATLLTAEQLSSVAEKLPGWTLADQRLQRQWRFRNFVEAFGFMTRVALLAEAMNHHPEW
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SNVYATVTIELTTHDVNGLSDRDLKLAEAINLLEPG
CCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TATLLTAEQLSSVAEKLPGWTLADQRLQRQWRFRNFVEAFGFMTRVALLAEAMNHHPEW
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SNVYATVTIELTTHDVNGLSDRDLKLAEAINLLEPG
CCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA