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The map label for this gene is pyrC' [H]

Identifier: 33863521

GI number: 33863521

Start: 1342185

End: 1343441

Strand: Direct

Name: pyrC' [H]

Synonym: PMT1253

Alternate gene names: 33863521

Gene position: 1342185-1343441 (Clockwise)

Preceding gene: 33863520

Following gene: 33863523

Centisome position: 55.67

GC content: 57.2

Gene sequence:

>1257_bases
ATGCCCGAGGCACAACTTCTAGACCCCATAAGGATCCTGCACGGGTCGGATCAACCTGTCGTTGAAGATGCTGTGCTGAT
CAGAGACAACCATCTGATCGCCTTTGGAGCGAAGGCACGTATACAGGCTCAACAGCTCGGGCTGCCCCCCAAATCAGCCA
GCCAACAACTACTCGCCCCCTGTCTTGTAGACCCCCATTCCATCCTTGAAGATCCAATCAGTGGTCATTGCGAAACCCTT
GCAAGCCTGAGACATGCAGCTGCTGCTGCCGGTTATGGCCAACTAGCTCTGCTACCCCGCAGTTCCTCCTGGCGTGATCG
CCCCGAAAGATTGCAGGGATTTTTAAATCCAAATAGCGATGTCGACATTCACTTGTGGGGCAGCTTTAGCAGAGATGGTG
CCGGCAGCGAACTATCCCCCCACGCGGATTTAGTGCAACACGGTGCCGTAGGGCTGGCAAACGACGATCTAATCCTGCCG
ATCGCTCTCCTACAGCGAGGACTGGTGCTAGGCGAAATGGGGTCAGCCCCTGTGTTAATCGCCCCCAGAGATGAAAAAAT
TCAAGGTGGCGGGATGGTGCGCGAAGGCGTTGAAACACTACGAGCGGGCTGGGCACCTGACCCCTTCGCCAGCGAAACCC
TCCCCCTGGGACAACTTCTCGAACTTCATCGGCAGCACCCTGAACGTTCCCTAAGACTGATGAACCTGGCCACTGCCCCT
GGAGTCGCCATCTTGGGGTCCTGTCCCTCCCGGCCTATGGCCAGCGTGTGCTGGTGGCATCTGGTGACTGACCAAAGCAA
ACTTGATCCCACAGAGCTTGGATGGAGGGTCAGCCCATCTCTTGGCAGTCCTAGAGATCGAGCCGCCTTGATCAAGGCCC
TCGCCAATGGCACCCTCACGGCCGTGGCTGTCCATGCCATACCCCTGGATGAGGAAGATACCCAACTGCCTCCCAATCAG
CTTGAGCCTGGCCTAGCAGGCCATCAACTCGTGCTGCCTGCGCTTTGGCAAGAGCTTGTGGTCAAAGCTGGTTGGTCTGT
AGAGCAGCTTTGGCATGCTCTGAGTTTTGGACCGTCAAAAATGCTCAACCTGCCCGAAGAACGCTTGACCGTTGGCAGCC
GGCGCTGGCTGATGTTCGACCCTGATCAGCTCTGGATCCAAGATCGGCACAGTGATGATGCCCCCAAAGCCGCTAATCAA
CCCTGGCAGGGCTGCCAACTGCAAGGCCGTGTCGTGGCATGTGGACTCAGGGAATAA

Upstream 100 bases:

>100_bases
GCTACAGATCCCGGCCAACCTGCAGTGGTGACCTCTCTCAACCTCACCTCTCACCTTGGTGGTGTGCTCGATCGCACAGC
TGCTGGGGCGCTCTAACGTG

Downstream 100 bases:

>100_bases
GTGACCCGAAACGATCAAAAGGCCAAAAACGCCATAAAGCACGCCCGAGGATCTCTTTCTCAGGCAGAAATCCCCAAATT
CGTCCATCAGTGCTATTGCT

Product: dihydroorotase

Products: N-carbamoyl-L-aspartate

Alternate protein names: Aspartate carbamoyltransferase 42 kDa non-catalytic chain [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MPEAQLLDPIRILHGSDQPVVEDAVLIRDNHLIAFGAKARIQAQQLGLPPKSASQQLLAPCLVDPHSILEDPISGHCETL
ASLRHAAAAAGYGQLALLPRSSSWRDRPERLQGFLNPNSDVDIHLWGSFSRDGAGSELSPHADLVQHGAVGLANDDLILP
IALLQRGLVLGEMGSAPVLIAPRDEKIQGGGMVREGVETLRAGWAPDPFASETLPLGQLLELHRQHPERSLRLMNLATAP
GVAILGSCPSRPMASVCWWHLVTDQSKLDPTELGWRVSPSLGSPRDRAALIKALANGTLTAVAVHAIPLDEEDTQLPPNQ
LEPGLAGHQLVLPALWQELVVKAGWSVEQLWHALSFGPSKMLNLPEERLTVGSRRWLMFDPDQLWIQDRHSDDAPKAANQ
PWQGCQLQGRVVACGLRE

Sequences:

>Translated_418_residues
MPEAQLLDPIRILHGSDQPVVEDAVLIRDNHLIAFGAKARIQAQQLGLPPKSASQQLLAPCLVDPHSILEDPISGHCETL
ASLRHAAAAAGYGQLALLPRSSSWRDRPERLQGFLNPNSDVDIHLWGSFSRDGAGSELSPHADLVQHGAVGLANDDLILP
IALLQRGLVLGEMGSAPVLIAPRDEKIQGGGMVREGVETLRAGWAPDPFASETLPLGQLLELHRQHPERSLRLMNLATAP
GVAILGSCPSRPMASVCWWHLVTDQSKLDPTELGWRVSPSLGSPRDRAALIKALANGTLTAVAVHAIPLDEEDTQLPPNQ
LEPGLAGHQLVLPALWQELVVKAGWSVEQLWHALSFGPSKMLNLPEERLTVGSRRWLMFDPDQLWIQDRHSDDAPKAANQ
PWQGCQLQGRVVACGLRE
>Mature_417_residues
PEAQLLDPIRILHGSDQPVVEDAVLIRDNHLIAFGAKARIQAQQLGLPPKSASQQLLAPCLVDPHSILEDPISGHCETLA
SLRHAAAAAGYGQLALLPRSSSWRDRPERLQGFLNPNSDVDIHLWGSFSRDGAGSELSPHADLVQHGAVGLANDDLILPI
ALLQRGLVLGEMGSAPVLIAPRDEKIQGGGMVREGVETLRAGWAPDPFASETLPLGQLLELHRQHPERSLRLMNLATAPG
VAILGSCPSRPMASVCWWHLVTDQSKLDPTELGWRVSPSLGSPRDRAALIKALANGTLTAVAVHAIPLDEEDTQLPPNQL
EPGLAGHQLVLPALWQELVVKAGWSVEQLWHALSFGPSKMLNLPEERLTVGSRRWLMFDPDQLWIQDRHSDDAPKAANQP
WQGCQLQGRVVACGLRE

Specific function: Non-functional DHOase [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Type 2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004722 [H]

Pfam domain/function: NA

EC number: 3.5.2.3

Molecular weight: Translated: 45377; Mature: 45246

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAQLLDPIRILHGSDQPVVEDAVLIRDNHLIAFGAKARIQAQQLGLPPKSASQQLLAP
CCCCHHCCHHHHHCCCCCCHHHCEEEEECCEEEEECCCCEEEHHHCCCCCCHHHHHHHHH
CLVDPHSILEDPISGHCETLASLRHAAAAAGYGQLALLPRSSSWRDRPERLQGFLNPNSD
HHCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCCCC
VDIHLWGSFSRDGAGSELSPHADLVQHGAVGLANDDLILPIALLQRGLVLGEMGSAPVLI
EEEEEECCCCCCCCCCCCCCHHHHHHCCCCEECCCCEEEEHHHHHCCCEEECCCCCCEEE
APRDEKIQGGGMVREGVETLRAGWAPDPFASETLPLGQLLELHRQHPERSLRLMNLATAP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHEEHEECCCC
GVAILGSCPSRPMASVCWWHLVTDQSKLDPTELGWRVSPSLGSPRDRAALIKALANGTLT
CEEEECCCCCCCHHHHHHHHEECCCCCCCHHHCCEEECCCCCCCHHHHHHHHHHHCCCEE
AVAVHAIPLDEEDTQLPPNQLEPGLAGHQLVLPALWQELVVKAGWSVEQLWHALSFGPSK
EEEEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
MLNLPEERLTVGSRRWLMFDPDQLWIQDRHSDDAPKAANQPWQGCQLQGRVVACGLRE
HHCCCHHHHCCCCCEEEEECCHHHEEECCCCCCCCCCCCCCCCCCEECCEEEEEECCC
>Mature Secondary Structure 
PEAQLLDPIRILHGSDQPVVEDAVLIRDNHLIAFGAKARIQAQQLGLPPKSASQQLLAP
CCCHHCCHHHHHCCCCCCHHHCEEEEECCEEEEECCCCEEEHHHCCCCCCHHHHHHHHH
CLVDPHSILEDPISGHCETLASLRHAAAAAGYGQLALLPRSSSWRDRPERLQGFLNPNSD
HHCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCCCC
VDIHLWGSFSRDGAGSELSPHADLVQHGAVGLANDDLILPIALLQRGLVLGEMGSAPVLI
EEEEEECCCCCCCCCCCCCCHHHHHHCCCCEECCCCEEEEHHHHHCCCEEECCCCCCEEE
APRDEKIQGGGMVREGVETLRAGWAPDPFASETLPLGQLLELHRQHPERSLRLMNLATAP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHEEHEECCCC
GVAILGSCPSRPMASVCWWHLVTDQSKLDPTELGWRVSPSLGSPRDRAALIKALANGTLT
CEEEECCCCCCCHHHHHHHHEECCCCCCCHHHCCEEECCCCCCCHHHHHHHHHHHCCCEE
AVAVHAIPLDEEDTQLPPNQLEPGLAGHQLVLPALWQELVVKAGWSVEQLWHALSFGPSK
EEEEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
MLNLPEERLTVGSRRWLMFDPDQLWIQDRHSDDAPKAANQPWQGCQLQGRVVACGLRE
HHCCCHHHHCCCCCEEEEECCHHHEEECCCCCCCCCCCCCCCCCCEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-dihydroorotate; H2O

Specific reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]