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The map label for this gene is frr

Identifier: 33863513

GI number: 33863513

Start: 1332897

End: 1333445

Strand: Direct

Name: frr

Synonym: PMT1245

Alternate gene names: 33863513

Gene position: 1332897-1333445 (Clockwise)

Preceding gene: 33863512

Following gene: 33863514

Centisome position: 55.29

GC content: 46.99

Gene sequence:

>549_bases
ATGTCGAACCAGGAACTCAAAGACAACATGCACAAATCAGTGGAGGCCACACAGCGCAACTTCGCCACCATCCGTACTGG
ACGCGCCAACCCGTCACTACTTGATCGAATCAACGTTGAGTATTACGGCACAGAAACGCCCCTGAAATCTCTAGCAACAA
TATCCACCCCTGATTCACAGACGATTGCCATACAGCCCTTTGATAATGGATCAATGGGCCTGATTGAAAAAGCCATTGCC
ACTAGTGATTTGGGCTTGACACCCAACAATGACGGCAAGATCATTCGCATCAATGTGCCGCCGCTAACTGAAGAGCGCCG
CAAAGAGTTCTGCAAACTGGCAGCAAGATATGCAGAAGAAGGCAAAGTAGCCCTGCGCAACATCCGTCGCGATGCAATTG
ATAAAGTGAAAAAGCTAGAAAAAGATGCTGAGCTCTCTAAAGATCAGAGCCATGATGAACAGGATGGGATACAAAAACTC
ACCGACACATTCATCACTGAAATTGAAAAATACCTCGCCGAAAAAGAAGCCGACATTCTCAAGGTTTGA

Upstream 100 bases:

>100_bases
AAGCAGTGGCTGGCGAAGCAATCGGCTCCCGTATCAGCAATGCAACCTAAACAGGCCATCCCAACTCATCCCTTCACCCA
GCCTTCGCCTCTCTGAAGCC

Downstream 100 bases:

>100_bases
GCACTCGCGATGTGCTGGTCATCGGAGCAGGCGCCGCTGGATCTGCGGCAGCTTTCCATCTGGCTGCAGCCGGCCAACGC
GTCACACTGCTCGAACAGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSNQELKDNMHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDNGSMGLIEKAIA
TSDLGLTPNNDGKIIRINVPPLTEERRKEFCKLAARYAEEGKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKL
TDTFITEIEKYLAEKEADILKV

Sequences:

>Translated_182_residues
MSNQELKDNMHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDNGSMGLIEKAIA
TSDLGLTPNNDGKIIRINVPPLTEERRKEFCKLAARYAEEGKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKL
TDTFITEIEKYLAEKEADILKV
>Mature_181_residues
SNQELKDNMHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDNGSMGLIEKAIAT
SDLGLTPNNDGKIIRINVPPLTEERRKEFCKLAARYAEEGKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKLT
DTFITEIEKYLAEKEADILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=29.608938547486, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786368, Length=172, Percent_Identity=54.0697674418605, Blast_Score=182, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=29.5454545454545, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PROMM (Q7V6C1)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895073.1
- ProteinModelPortal:   Q7V6C1
- SMR:   Q7V6C1
- STRING:   Q7V6C1
- GeneID:   1728707
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1245
- NMPDR:   fig|74547.1.peg.1240
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   PMAR74547:PMT1245-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20476; Mature: 20345

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQELKDNMHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQ
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCEEECCCCHHHHHHCCCCCCCC
TIAIQPFDNGSMGLIEKAIATSDLGLTPNNDGKIIRINVPPLTEERRKEFCKLAARYAEE
EEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHC
GKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKLTDTFITEIEKYLAEKEADIL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC
>Mature Secondary Structure 
SNQELKDNMHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQ
CCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCEEECCCCHHHHHHCCCCCCCC
TIAIQPFDNGSMGLIEKAIATSDLGLTPNNDGKIIRINVPPLTEERRKEFCKLAARYAEE
EEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHC
GKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKLTDTFITEIEKYLAEKEADIL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642