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The map label for this gene is clpC [H]

Identifier: 33863332

GI number: 33863332

Start: 1143769

End: 1146348

Strand: Direct

Name: clpC [H]

Synonym: PMT1061

Alternate gene names: 33863332

Gene position: 1143769-1146348 (Clockwise)

Preceding gene: 33863331

Following gene: 33863333

Centisome position: 47.44

GC content: 50.27

Gene sequence:

>2580_bases
ATGTTCGAGCGGTTTACCGAGAAGGCCATCAAGGTGATCATGCTGGCCCAGGAAGAGGCCCGGCGTCTTGGTCATAATTT
CGTGGGCACCGAGCAGATTCTTTTGGGATTGATCGGTGAGGGCACAGGTGTGGCAGCGAAGGTTCTCAAGTCAATGAGCG
TGAACCTTAAAGACGCCCGCGTTGAAGTTGAAAAGATCATTGGCCGTGGTTCAGGCTTCGTCGCCGTAGAAATCCCCTTT
ACTCCCAGAGCAAAGCGCGTACTAGAACTCTCTCTAGAAGAAGCCCGACAACTTGGCCACAATTACATCGGTACAGAACA
TTTACTGCTTGGTCTCATCCGAGAAGGAGAGGGTGTAGCAGCCCGAGTCCTCGAAAACCTTGGTGTAGACCTAGCAAAGG
TGCGCACCCAAGTAATCCGCATGCTCGGAGAAACCGCCGAGGTCACTGCAGGCGGAGGTGGAGGCAAAGGCTCAACGAAA
ACAGCCACACTTGATGAATTCGGCAGCAACCTGACCCAGCTAGCCAATGAATCCAAGCTTGATCCTGTTGTCGGGCGACA
AAATGAAATCGATCGTGTTATTCAGATCCTCGGAAGACGCACAAAGAACAACCCTGTACTGATTGGAGAGCCTGGAGTTG
GGAAAACAGCAATTGCTGAAGGCCTAGCTCAACGCATCCAACAGGGAGATATTCCCGACATCCTTGAAGAAAAGAGAGTT
CTAACCCTCGACATCGGCCTGCTAGTTGCTGGAACCAAATACCGGGGAGAGTTCGAAGAACGGCTCAAAAAGATCATGGA
AGAGATCAAAGCCGCAGGCAACGTGATCCTTGTCATCGATGAAGTGCACACACTCATTGGGGCAGGCGCTGCAGAAGGTG
CCATCGATGCCGCCAACATTCTCAAACCAGCACTAGCTAGAGGAGAACTGCAGTGCATAGGTGCCACCACTCTTGACGAA
TATCGAAAACACATCGAACGTGATGCTGCCCTAGAACGCCGATTTCAGCCAGTCATGGTTGGCGAACCATCGATCGCTGA
AACCATTGAGATCCTGCAAGGATTGAGGGAGCGCTACGAACAGCATCACCGCCTAAAAATCACAGACGAAGCCCTAGATG
CCGCAGCAAACCTAGGCGATCGCTATATCTCTGATCGCTTCCTGCCGGATAAGGCCATCGACTTAATCGATGAAGCTGGC
AGCCGCGTGCGTTTGCTTAACTCCAAACTTCCCCCTGCGGCAAAAGAGGTTGACAAAGAATTACGCAAGGTTCAAAAGGA
AAAAGAAGATGCCGTTCGTGATCAGGACTTCGCCAAAGCCGGGGAATTACGTGAAAAAGAAGTTGAGCTAAGAGAAAAGA
TCCGCACTCTGCTTCAAAGCAGTCGCCAAGGCAGTGAGGAATCGCCCCCCGCTGAGGCGGAAAATGCTGTTCGTTCCAGC
GATGAGACTCCAACACCTCAACCTGAAAAAAACACAACAGCTGCATTAATTCCTCATCTCACCACACCACTGGTGACAGA
AGAAGATATTGCCAACATCGTGGCAGCTTGGACCGGAGTACCTGTACAAAAGCTCACCGAAAGCGAATCAGTGAAGCTCC
TAAACATGGAGGAAACCCTCCACCAGAGGCTGATTGGCCAAGATGAAGCCGTCAAAGCAGTCTCGAAAGCCATCCGTCGA
GCCAGGGTAGGCCTCAAAAACCCCAATCGCCCCATTGCCAGTTTCATCTTTTCAGGCCCTACTGGCGTCGGCAAAACCGA
ACTAACCAAAGCTCTAGCCACCTACTTCTTTGGTAGCGAAGAAGCCATGATCCGACTAGACATGTCGGAATTCATGGAGC
GACATACGGTCAGCAAGCTGATCGGATCACCTCCTGGCTATGTGGGGTTCAACGAAGGGGGACAACTCACCGAAGCTGTT
CGTCGCAGACCTTATACCGTTGTGCTCTTCGACGAAATCGAAAAGGCACACCCAGATGTTTTTAACCTGCTGCTTCAATT
ATTGGAAGATGGTCGACTAACTGACTCCAAAGGAAGAACAGTGGACTTCAAGAATACATTGATCATTATGACTTCGAATA
TCGGTTCAAAAGTGATTGAGAAAGGAGGCGGAGGACTTGGCTTCGAATTCTCAGGTGAAAACGCAGAAGACAGTCAATAC
AACCGAATCAAATCCCTTGTCAACGAAGAACTAAAACAATACTTCCGTCCTGAATTTCTGAACCGTCTCGATGAAATTAT
CGTCTTCCGCCAACTCAGTAGAAATGAGGTGAAAGAAATCGCTGAGATCATGCTTCAAGAAGTGTTCTCTCGCATGCAAG
ACAAAGGGATCACTCTCACTGTTTCAGATGCATTCAAAGAACGACTAGTGGAAGAGGGATACAACCCCTCTTATGGAGCG
AGGCCGCTACGAAGGGCCGTCATGCGACTCATGGAAGACAGTCTTGCTGAGGAAGTGCTTACTGGCCGCATCAAGGACGG
TGATGCTGCGGAGATGGATGTGGATGACAACAAGCAAATCGTTGTACGCCATGTCAGCAAAACTACTGCCACACCGGAAC
TCGCTGGAGCAGGAGTCTGA

Upstream 100 bases:

>100_bases
CTAACTCCCTTGCAGCAAAGGGACTAGGCCAAATAATCCAACAGCTCACATTCCAACACCAACCCTGATAAGTTAGAGAT
AGATTCACGTGCCCCGGACC

Downstream 100 bases:

>100_bases
CACCTCTCCTACATCAATGAACAAAAACAATTTGCCTGAGGAGGTGTCTCACTGCGCTCACTCCATAGCCCCCGAAAAGG
TTGTTAGGGGAGAAAGGGCG

Product: ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 859

Protein sequence:

>859_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDARVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTK
TATLDEFGSNLTQLANESKLDPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKAAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPAAKEVDKELRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQGSEESPPAEAENAVRSS
DETPTPQPEKNTTAALIPHLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETLHQRLIGQDEAVKAVSKAIRR
ARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAV
RRRPYTVVLFDEIEKAHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEDSQY
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRNEVKEIAEIMLQEVFSRMQDKGITLTVSDAFKERLVEEGYNPSYGA
RPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQIVVRHVSKTTATPELAGAGV

Sequences:

>Translated_859_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDARVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTK
TATLDEFGSNLTQLANESKLDPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKAAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPAAKEVDKELRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQGSEESPPAEAENAVRSS
DETPTPQPEKNTTAALIPHLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETLHQRLIGQDEAVKAVSKAIRR
ARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAV
RRRPYTVVLFDEIEKAHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEDSQY
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRNEVKEIAEIMLQEVFSRMQDKGITLTVSDAFKERLVEEGYNPSYGA
RPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQIVVRHVSKTTATPELAGAGV
>Mature_859_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDARVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTK
TATLDEFGSNLTQLANESKLDPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKAAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPAAKEVDKELRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQGSEESPPAEAENAVRSS
DETPTPQPEKNTTAALIPHLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETLHQRLIGQDEAVKAVSKAIRR
ARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAV
RRRPYTVVLFDEIEKAHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEDSQY
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRNEVKEIAEIMLQEVFSRMQDKGITLTVSDAFKERLVEEGYNPSYGA
RPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQIVVRHVSKTTATPELAGAGV

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=337, Percent_Identity=38.8724035608309, Blast_Score=209, Evalue=8e-54,
Organism=Escherichia coli, GI1788943, Length=885, Percent_Identity=46.1016949152542, Blast_Score=746, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=407, Percent_Identity=41.031941031941, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6320464, Length=709, Percent_Identity=48.6600846262341, Blast_Score=641, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=873, Percent_Identity=36.9988545246277, Blast_Score=545, Evalue=1e-155,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 94785; Mature: 94785

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
VEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTKTATLDEFGSNLTQLANESKL
HHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHCHHHHHHHCCCCC
DPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKAAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEHHHEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAGSRVRLLNSKLPPAAKEVDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHH
LRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQGSEESPPAEAENAVRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
DETPTPQPEKNTTAALIPHLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETL
CCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCEEEECHHHHH
HQRLIGQDEAVKAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSE
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
EAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEIEKAHPDV
CCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHH
FNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEDSQY
HHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEEECCCCCCCHHH
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRNEVKEIAEIMLQEVFSRMQDKGITLT
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VSDAFKERLVEEGYNPSYGARPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQI
EHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
VVRHVSKTTATPELAGAGV
EEEEHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
VEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTKTATLDEFGSNLTQLANESKL
HHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHCHHHHHHHCCCCC
DPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKAAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEHHHEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAGSRVRLLNSKLPPAAKEVDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHH
LRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQGSEESPPAEAENAVRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
DETPTPQPEKNTTAALIPHLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETL
CCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCEEEECHHHHH
HQRLIGQDEAVKAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSE
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
EAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEIEKAHPDV
CCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHH
FNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEDSQY
HHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEEECCCCCCCHHH
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRNEVKEIAEIMLQEVFSRMQDKGITLT
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VSDAFKERLVEEGYNPSYGARPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQI
EHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
VVRHVSKTTATPELAGAGV
EEEEHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]