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The map label for this gene is ompR [H]

Identifier: 33863077

GI number: 33863077

Start: 882443

End: 883168

Strand: Reverse

Name: ompR [H]

Synonym: PMT0805

Alternate gene names: 33863077

Gene position: 883168-882443 (Counterclockwise)

Preceding gene: 33863079

Following gene: 33863076

Centisome position: 36.63

GC content: 52.89

Gene sequence:

>726_bases
ATGGAACGCTCCTCGATGATCTGGGTTGTGGACGATGACCCAGAACTGCGTCAGATGGTGGGTACCTATCTGATTGACCA
GGGTTATGACGTTCGCTGTCTCAGCGATGTCAAGCAACTGGAAGCACGGTTGGAATTTCAACGACCTGATCTTGTTGTCC
TTGACTTGATGCTGCCGGGTGATGATGGCCTTTCCGCTCTGCGTCGTTTGCGTGATGCAGGGGATGATTTGCCTGTTGTG
ATGCTTACCGCGAGGGGGGAGGCCGTTGATCGGATCATCGGTCTCGAGCAAGGTGCAGACGATTACCTCGGCAAGCCATT
CCTTCCACGAGAGCTTTCTGCTCGTATTGAAGCCGTTTTGAGACGGCGCTGTGCGCTTCCCGCTGGCACCCCTTTAGCCG
AGGGTGGCGATGTGGTTTTTGGTGGGAATGTGTTGAATCTTTCCGCTCGTACCCTGACCCAAAATGGTTCTCCAGTTGTG
ATTACGAGTGGAGAATTCAGCTTGTTGTCCGCCTTTGTACAACATCCTCATCGCCCTCTTTCTAGGGAAAGATTGATTGA
ACTCGCACGTGGGCCAGCTTGTGATACAGATAGTCGAAGCATGGATGTTCAGGTTTCGAGGGTGAGAAGGTTGGTCGAAC
CCGATTCCAGTCGACCTCGCTATATCCAGACGGTATGGGGCTATGGATATGTTTTTGTCCCTGATGGTGAGCCCAGGTCT
CGCTGA

Upstream 100 bases:

>100_bases
AAAGCTCTTTGAGCTGTGACATGCTCCAACCCCTTTAAAAAAAGCGATAGAGATTGTCTATACCATCGAGGAACAGTGGC
TTCTAGAGCACGCAATAGTG

Downstream 100 bases:

>100_bases
TGACGCGGACACAACGCAGGGCGGCGATCGTGTTCACTGCTTTGGGCTGGAGTGGCGTTGGTCTTGGCAGTTGGGCGCTT
TGTTTATTGGTTTTGCAGGT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MERSSMIWVVDDDPELRQMVGTYLIDQGYDVRCLSDVKQLEARLEFQRPDLVVLDLMLPGDDGLSALRRLRDAGDDLPVV
MLTARGEAVDRIIGLEQGADDYLGKPFLPRELSARIEAVLRRRCALPAGTPLAEGGDVVFGGNVLNLSARTLTQNGSPVV
ITSGEFSLLSAFVQHPHRPLSRERLIELARGPACDTDSRSMDVQVSRVRRLVEPDSSRPRYIQTVWGYGYVFVPDGEPRS
R

Sequences:

>Translated_241_residues
MERSSMIWVVDDDPELRQMVGTYLIDQGYDVRCLSDVKQLEARLEFQRPDLVVLDLMLPGDDGLSALRRLRDAGDDLPVV
MLTARGEAVDRIIGLEQGADDYLGKPFLPRELSARIEAVLRRRCALPAGTPLAEGGDVVFGGNVLNLSARTLTQNGSPVV
ITSGEFSLLSAFVQHPHRPLSRERLIELARGPACDTDSRSMDVQVSRVRRLVEPDSSRPRYIQTVWGYGYVFVPDGEPRS
R
>Mature_241_residues
MERSSMIWVVDDDPELRQMVGTYLIDQGYDVRCLSDVKQLEARLEFQRPDLVVLDLMLPGDDGLSALRRLRDAGDDLPVV
MLTARGEAVDRIIGLEQGADDYLGKPFLPRELSARIEAVLRRRCALPAGTPLAEGGDVVFGGNVLNLSARTLTQNGSPVV
ITSGEFSLLSAFVQHPHRPLSRERLIELARGPACDTDSRSMDVQVSRVRRLVEPDSSRPRYIQTVWGYGYVFVPDGEPRS
R

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=52.9661016949153, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=39.0350877192982, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.4782608695652, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=33.4745762711864, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786784, Length=189, Percent_Identity=38.6243386243386, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=33.1877729257642, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=33.9055793991416, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=33.6170212765957, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=34.4827586206897, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.5309734513274, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=35.7446808510638, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.6283185840708, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=30.379746835443, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=31.1688311688312, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=31.304347826087, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=32.4786324786325, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26818; Mature: 26818

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSSMIWVVDDDPELRQMVGTYLIDQGYDVRCLSDVKQLEARLEFQRPDLVVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECC
DDGLSALRRLRDAGDDLPVVMLTARGEAVDRIIGLEQGADDYLGKPFLPRELSARIEAVL
CHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHH
RRRCALPAGTPLAEGGDVVFGGNVLNLSARTLTQNGSPVVITSGEFSLLSAFVQHPHRPL
HHHHCCCCCCCCCCCCCEEECCCEEEEEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCC
SRERLIELARGPACDTDSRSMDVQVSRVRRLVEPDSSRPRYIQTVWGYGYVFVPDGEPRS
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEEECCCCCCC
R
C
>Mature Secondary Structure
MERSSMIWVVDDDPELRQMVGTYLIDQGYDVRCLSDVKQLEARLEFQRPDLVVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECC
DDGLSALRRLRDAGDDLPVVMLTARGEAVDRIIGLEQGADDYLGKPFLPRELSARIEAVL
CHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHH
RRRCALPAGTPLAEGGDVVFGGNVLNLSARTLTQNGSPVVITSGEFSLLSAFVQHPHRPL
HHHHCCCCCCCCCCCCCEEECCCEEEEEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCC
SRERLIELARGPACDTDSRSMDVQVSRVRRLVEPDSSRPRYIQTVWGYGYVFVPDGEPRS
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEEECCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]