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The map label for this gene is nadA [H]

Identifier: 33862934

GI number: 33862934

Start: 717593

End: 718594

Strand: Reverse

Name: nadA [H]

Synonym: PMT0661

Alternate gene names: 33862934

Gene position: 718594-717593 (Counterclockwise)

Preceding gene: 33862937

Following gene: 33862931

Centisome position: 29.81

GC content: 44.61

Gene sequence:

>1002_bases
ATGGTCCGAATGACCGCTGTTTGCACCGCCAAGACGGTCTCTCCAGTGCCATCAACTAGGAAAGAATTAAAGGGTGCCAT
TGCTGAACTACGCAAAAAACTCAATGCCGTGATCCTGGCTCACTACTACCAGGATCCAGAGATCCAAGACATCGCAGATT
TCATTGGGGACTCCCTGGAACTATCACGTAGAGCTGCTAGCACAAATGCTGATGTAATCGTGTTCTGCGGGGTTCACTTC
ATGGCTGAAACAGCAAAGATTCTCAGCCCGGAAAAAATTGTATTGCTACCAGATCTCGAAGCGGGGTGCTCCCTTGCTGA
TGACTGCCCAGCCGATGAGTTTGCTGCTTTCAGAGACAAGCACCCAGACCACATTGTGGTGAGCTATATCAACTGCACAG
CTGCTGTTAAGGCCCAAAGCGATCTGATCTGTACAAGTAGCAACGCTGTAGAACTTGTAAATCAATTACCGAAGGATCAA
CCAATCCTTTTTGCTCCAGATCAAAACTTGGGCAGATGGGTTCAAAAGCAGAGCGGCAGAAAACTGACGATCTGGCCTGG
ACGCTGCATGGTGCATGAAACATTCAGCGAAGAAGCTCTACTGAAATTAAAAATCATGCACCCCGAGGCAAAGGTAATAG
CCCATCCGGAGTGCCTAGAAAATTTACTAGAGTTGGCGGATTATATTGGCTCAACGAGCAAATTACTTGAATTTACCGAG
ATAAGTTCATGCACAAAATTTATCGTACTAACAGAGCCAGGAATCCTACACCAGATGAAATTGAAGAACCCAAAAAAAGA
ATTTATGGATGTTCCAGGTATTGACGGATGTAGTTGCAATGAATGCCCATATATGCGATTGAATACATTAGAAAAGCTAT
GGAGCTGCTTAAGCACAATGAAGCCATCAATAGAAATCGAAGAGGGGGTACGTCAAAAGGCTTTTATTCCTATTCAACGA
ATGCTAAACATGAAAGAAACACAGGAGGCTAGTGAACATTAA

Upstream 100 bases:

>100_bases
GTTCTGATCATCAGGTGTCCATACACCATGGAGGTCTCCAACAATGGCGAGGCTCTGGTGTGACGTGGCAAATGTCTAGG
CTATGGCCATACTGCCCTAG

Downstream 100 bases:

>100_bases
TTGTTCACTGTAAAGCTGAAGGTCAACACAACAAGAGAGAACTCTGAGAAATAATTCTTATTAGTTTAAAGATGGCGTGG
AGAAAACTAGCCAATACTAC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MVRMTAVCTAKTVSPVPSTRKELKGAIAELRKKLNAVILAHYYQDPEIQDIADFIGDSLELSRRAASTNADVIVFCGVHF
MAETAKILSPEKIVLLPDLEAGCSLADDCPADEFAAFRDKHPDHIVVSYINCTAAVKAQSDLICTSSNAVELVNQLPKDQ
PILFAPDQNLGRWVQKQSGRKLTIWPGRCMVHETFSEEALLKLKIMHPEAKVIAHPECLENLLELADYIGSTSKLLEFTE
ISSCTKFIVLTEPGILHQMKLKNPKKEFMDVPGIDGCSCNECPYMRLNTLEKLWSCLSTMKPSIEIEEGVRQKAFIPIQR
MLNMKETQEASEH

Sequences:

>Translated_333_residues
MVRMTAVCTAKTVSPVPSTRKELKGAIAELRKKLNAVILAHYYQDPEIQDIADFIGDSLELSRRAASTNADVIVFCGVHF
MAETAKILSPEKIVLLPDLEAGCSLADDCPADEFAAFRDKHPDHIVVSYINCTAAVKAQSDLICTSSNAVELVNQLPKDQ
PILFAPDQNLGRWVQKQSGRKLTIWPGRCMVHETFSEEALLKLKIMHPEAKVIAHPECLENLLELADYIGSTSKLLEFTE
ISSCTKFIVLTEPGILHQMKLKNPKKEFMDVPGIDGCSCNECPYMRLNTLEKLWSCLSTMKPSIEIEEGVRQKAFIPIQR
MLNMKETQEASEH
>Mature_333_residues
MVRMTAVCTAKTVSPVPSTRKELKGAIAELRKKLNAVILAHYYQDPEIQDIADFIGDSLELSRRAASTNADVIVFCGVHF
MAETAKILSPEKIVLLPDLEAGCSLADDCPADEFAAFRDKHPDHIVVSYINCTAAVKAQSDLICTSSNAVELVNQLPKDQ
PILFAPDQNLGRWVQKQSGRKLTIWPGRCMVHETFSEEALLKLKIMHPEAKVIAHPECLENLLELADYIGSTSKLLEFTE
ISSCTKFIVLTEPGILHQMKLKNPKKEFMDVPGIDGCSCNECPYMRLNTLEKLWSCLSTMKPSIEIEEGVRQKAFIPIQR
MLNMKETQEASEH

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=312, Percent_Identity=42.6282051282051, Blast_Score=259, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37174; Mature: 37174

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRMTAVCTAKTVSPVPSTRKELKGAIAELRKKLNAVILAHYYQDPEIQDIADFIGDSLE
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCCHHH
LSRRAASTNADVIVFCGVHFMAETAKILSPEKIVLLPDLEAGCSLADDCPADEFAAFRDK
HHHHHCCCCCCEEEEECHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCC
HPDHIVVSYINCTAAVKAQSDLICTSSNAVELVNQLPKDQPILFAPDQNLGRWVQKQSGR
CCCEEEEEEEEHEEEEECCCCEEEECCHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCC
KLTIWPGRCMVHETFSEEALLKLKIMHPEAKVIAHPECLENLLELADYIGSTSKLLEFTE
EEEEECCCEEEECCCCCCCEEEEEEECCCHHEEECHHHHHHHHHHHHHHCCHHHHHHHHH
ISSCTKFIVLTEPGILHQMKLKNPKKEFMDVPGIDGCSCNECPYMRLNTLEKLWSCLSTM
HHCCEEEEEECCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
KPSIEIEEGVRQKAFIPIQRMLNMKETQEASEH
CCCCCHHHCCHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MVRMTAVCTAKTVSPVPSTRKELKGAIAELRKKLNAVILAHYYQDPEIQDIADFIGDSLE
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCCHHH
LSRRAASTNADVIVFCGVHFMAETAKILSPEKIVLLPDLEAGCSLADDCPADEFAAFRDK
HHHHHCCCCCCEEEEECHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCC
HPDHIVVSYINCTAAVKAQSDLICTSSNAVELVNQLPKDQPILFAPDQNLGRWVQKQSGR
CCCEEEEEEEEHEEEEECCCCEEEECCHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCC
KLTIWPGRCMVHETFSEEALLKLKIMHPEAKVIAHPECLENLLELADYIGSTSKLLEFTE
EEEEECCCEEEECCCCCCCEEEEEEECCCHHEEECHHHHHHHHHHHHHHCCHHHHHHHHH
ISSCTKFIVLTEPGILHQMKLKNPKKEFMDVPGIDGCSCNECPYMRLNTLEKLWSCLSTM
HHCCEEEEEECCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
KPSIEIEEGVRQKAFIPIQRMLNMKETQEASEH
CCCCCHHHCCHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA