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The map label for this gene is 33862755

Identifier: 33862755

GI number: 33862755

Start: 533429

End: 534643

Strand: Reverse

Name: 33862755

Synonym: PMT0482

Alternate gene names: NA

Gene position: 534643-533429 (Counterclockwise)

Preceding gene: 33862756

Following gene: 33862754

Centisome position: 22.18

GC content: 39.75

Gene sequence:

>1215_bases
GTGGCGCTAGAGACTCCTGAAGCCATGGCAAATGAGTCATCCAATCATTCAGTATCTGGGAAAAGTGCAAATGACTACTT
CAAAGATGGTGAAAAAAAATTTCGTTCAAATGATTATCAAGGGGCAATTGATAGTTACAGCAAAGCAATTGACATCAATC
CAAATAATGCCATTGCATACAATAATCGAGGGAATGCAAAAGATGAACTAGGTGATTATCAAAGTGCACTGAATGATTAC
AACAAAGCAATTGATATCAACGGACTCGATGCCAGCTTTTACATCAATAGAGGTGTTGTTAAGAGGCACTCGAAAAACAT
CAAAGGGGCAATCGATGACTACACAAAAGCTATTGAACTAGATCAACAACATGCAACTGCCTATTACAATAGGGGGTTTG
CTAAATTCAATCAAAGCGACAACAAAGGTGCTATCAATGATTACAATAAGGCTCTTGCCCTAAATCCAAAACATGCAAAA
TCATACTACAATAGAGCGATTATCAAAAACAATATTAATGATATCAAAGGTGCAATTTCTGACTACACAAAGGCAATTGA
GGCCATGCCTCTTTTTGCCTTTGCCTATTACAATCGCGGCAATTTAATGGAGAGGCTGGGCCGAAGGCAAGCAGCTGTTA
CTGACCATGAGAAGGCACTAGAAATAAATCCACAACTTATCACTGCGATGAACGAGCGTGCTGAAAATAAAAACTTAGTT
GAGAATAAGGTTGTAAATAATATGAGCAATGAAGAAGACAGAAATCATCAGGATGCATTTTATTATTACAGCCAAGGCAA
TGCAGAACAAAAGCGAAGCAACAATCAATCAGCGATCGACTATTATACAAAGGCGATAGAAGTCAATCCATACTATGCCG
AGGCATACAACTACAGGGGCCTTGCTAAATACAACCTTTATGACTATCAAGCCGCACTTGATGATTACAGTAAGGCAATA
GAAATTAACTCGATATACGAAGATGCCTACATTGGATGCGGTCTTGCAAAGTCTGCATTAAGTGATTATCAAGGTGCCAT
TCGAGCCTATGAGAGGGTACTAGTCATTAACCCCAAGAATGTTGCTGCTTATAGAAATCGTGGTATTGCTAAAGAATTGG
AGGGAAATCTAGAGGGTGCTTGTTCTGATTGGAGGGAGGCCGCCTCTCTAGGAGATGCAGATGCTGCAGAATGGGTCAAG
GCACAATGTTGTTAA

Upstream 100 bases:

>100_bases
TCGAGCAATCACAGAGTTGGCGATTGCCAAGCCAGTCCTCTGAATGATTGAGTTAAAATACTGCCAGAAGCTTGGTTATG
GCGGGTAGAATCCGAATGAA

Downstream 100 bases:

>100_bases
GGTACTCGCTTCTGCAAACTGTGGAATCACAAAAAAGAAGCTGGGCAAAGCCAGTAAATGCTTCTTTCAATTTAACGCTG
AAGCCATGTTAATGACATGG

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MALETPEAMANESSNHSVSGKSANDYFKDGEKKFRSNDYQGAIDSYSKAIDINPNNAIAYNNRGNAKDELGDYQSALNDY
NKAIDINGLDASFYINRGVVKRHSKNIKGAIDDYTKAIELDQQHATAYYNRGFAKFNQSDNKGAINDYNKALALNPKHAK
SYYNRAIIKNNINDIKGAISDYTKAIEAMPLFAFAYYNRGNLMERLGRRQAAVTDHEKALEINPQLITAMNERAENKNLV
ENKVVNNMSNEEDRNHQDAFYYYSQGNAEQKRSNNQSAIDYYTKAIEVNPYYAEAYNYRGLAKYNLYDYQAALDDYSKAI
EINSIYEDAYIGCGLAKSALSDYQGAIRAYERVLVINPKNVAAYRNRGIAKELEGNLEGACSDWREAASLGDADAAEWVK
AQCC

Sequences:

>Translated_404_residues
MALETPEAMANESSNHSVSGKSANDYFKDGEKKFRSNDYQGAIDSYSKAIDINPNNAIAYNNRGNAKDELGDYQSALNDY
NKAIDINGLDASFYINRGVVKRHSKNIKGAIDDYTKAIELDQQHATAYYNRGFAKFNQSDNKGAINDYNKALALNPKHAK
SYYNRAIIKNNINDIKGAISDYTKAIEAMPLFAFAYYNRGNLMERLGRRQAAVTDHEKALEINPQLITAMNERAENKNLV
ENKVVNNMSNEEDRNHQDAFYYYSQGNAEQKRSNNQSAIDYYTKAIEVNPYYAEAYNYRGLAKYNLYDYQAALDDYSKAI
EINSIYEDAYIGCGLAKSALSDYQGAIRAYERVLVINPKNVAAYRNRGIAKELEGNLEGACSDWREAASLGDADAAEWVK
AQCC
>Mature_403_residues
ALETPEAMANESSNHSVSGKSANDYFKDGEKKFRSNDYQGAIDSYSKAIDINPNNAIAYNNRGNAKDELGDYQSALNDYN
KAIDINGLDASFYINRGVVKRHSKNIKGAIDDYTKAIELDQQHATAYYNRGFAKFNQSDNKGAINDYNKALALNPKHAKS
YYNRAIIKNNINDIKGAISDYTKAIEAMPLFAFAYYNRGNLMERLGRRQAAVTDHEKALEINPQLITAMNERAENKNLVE
NKVVNNMSNEEDRNHQDAFYYYSQGNAEQKRSNNQSAIDYYTKAIEVNPYYAEAYNYRGLAKYNLYDYQAALDDYSKAIE
INSIYEDAYIGCGLAKSALSDYQGAIRAYERVLVINPKNVAAYRNRGIAKELEGNLEGACSDWREAASLGDADAAEWVKA
QCC

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=355, Percent_Identity=29.2957746478873, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI32307150, Length=355, Percent_Identity=29.2957746478873, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310123097, Length=186, Percent_Identity=31.1827956989247, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI310131789, Length=186, Percent_Identity=31.1827956989247, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI310110582, Length=186, Percent_Identity=31.1827956989247, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI24308141, Length=188, Percent_Identity=29.7872340425532, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=299, Percent_Identity=28.7625418060201, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115532690, Length=299, Percent_Identity=28.7625418060201, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17647755, Length=295, Percent_Identity=28.135593220339, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24585827, Length=295, Percent_Identity=28.135593220339, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24585829, Length=295, Percent_Identity=28.135593220339, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 45434; Mature: 45303

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALETPEAMANESSNHSVSGKSANDYFKDGEKKFRSNDYQGAIDSYSKAIDINPNNAIAY
CCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCEEEECCCCEEEE
NNRGNAKDELGDYQSALNDYNKAIDINGLDASFYINRGVVKRHSKNIKGAIDDYTKAIEL
CCCCCCHHHHHHHHHHHHHHHCEEECCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHH
DQQHATAYYNRGFAKFNQSDNKGAINDYNKALALNPKHAKSYYNRAIIKNNINDIKGAIS
CHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHH
DYTKAIEAMPLFAFAYYNRGNLMERLGRRQAAVTDHEKALEINPQLITAMNERAENKNLV
HHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCCHHEECCHHHHHHHHHHHCCCHHH
ENKVVNNMSNEEDRNHQDAFYYYSQGNAEQKRSNNQSAIDYYTKAIEVNPYYAEAYNYRG
HHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHCCCCHHHHHHHHEEECCCHHHHHHCCCC
LAKYNLYDYQAALDDYSKAIEINSIYEDAYIGCGLAKSALSDYQGAIRAYERVLVINPKN
EEEECCHHHHHHHHHHHHHEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEECCCC
VAAYRNRGIAKELEGNLEGACSDWREAASLGDADAAEWVKAQCC
HHHHHCCCCHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ALETPEAMANESSNHSVSGKSANDYFKDGEKKFRSNDYQGAIDSYSKAIDINPNNAIAY
CCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCEEEECCCCEEEE
NNRGNAKDELGDYQSALNDYNKAIDINGLDASFYINRGVVKRHSKNIKGAIDDYTKAIEL
CCCCCCHHHHHHHHHHHHHHHCEEECCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHH
DQQHATAYYNRGFAKFNQSDNKGAINDYNKALALNPKHAKSYYNRAIIKNNINDIKGAIS
CHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHH
DYTKAIEAMPLFAFAYYNRGNLMERLGRRQAAVTDHEKALEINPQLITAMNERAENKNLV
HHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCCHHEECCHHHHHHHHHHHCCCHHH
ENKVVNNMSNEEDRNHQDAFYYYSQGNAEQKRSNNQSAIDYYTKAIEVNPYYAEAYNYRG
HHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHCCCCHHHHHHHHEEECCCHHHHHHCCCC
LAKYNLYDYQAALDDYSKAIEINSIYEDAYIGCGLAKSALSDYQGAIRAYERVLVINPKN
EEEECCHHHHHHHHHHHHHEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEECCCC
VAAYRNRGIAKELEGNLEGACSDWREAASLGDADAAEWVKAQCC
HHHHHCCCCHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]