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The map label for this gene is spoU [C]

Identifier: 33862607

GI number: 33862607

Start: 381328

End: 382155

Strand: Direct

Name: spoU [C]

Synonym: PMT0334

Alternate gene names: 33862607

Gene position: 381328-382155 (Clockwise)

Preceding gene: 33862606

Following gene: 33862608

Centisome position: 15.82

GC content: 57.85

Gene sequence:

>828_bases
TTGATTTCAAGTCGCCGCAATCCTCTGGTGCGGAGATTGAAATTCCTCGCTAGCAGCGAAGGTCGTCAAGAGCAGGCTTT
GTTGCTGCTTGAGGGAACCCACCTGCTTCAGGAAGTGTTGCGAACCACACACCGTCCTAAAGAGATTGTGGCGACCAACT
TTTGGCTGGAGCGTCATGGGGATCTTGTGCAGGCTTTGCCTGCAGAAACCTTGATTCATCAGGTCACCCCAAGTGTTTTG
GAGGCTTCGTTGACGACAGTCAGCCCAGATGGTGTCGCCAGCCTTGTGCCCCTTGACTCTCTTCCGCAGGCTGTTAATCA
AGCCAAGTTTGTGTTGGCTTTGGATCGGCTGCAGGATCCTGGCAACCTTGGCACCTTGCTGCGAACAGCCTTGGCGGCAG
AGGTGGAGGCGGTTTGGCTTGCGTCCGGGGCGGATCCCCTTAGCCCAAAAGTGTTGAGGGCTTCGGCGGGGGCCATCCTG
CAGTTGCCCTATCAGCGCTTCGGGTCATCAGGGCAGGAGGCCGTGGAGCAGTTGGCTGAGCAGCTTGAATGGGCTGCTAG
TCACGGTTTACAGGTCGTGGCCACCATGGTGCCGGGCTCTTCTGCAGCCCATTCTTGTTTGCCTTATTGGCAGCTGGACT
GGAGAAAACCGACTGTGTTGGTGCTGGGCAATGAGGGATCCGGCCTGCATCCGCGTCTGCAGGCGTGTTGTACTGATTGC
GTGACCTTGCCGCATAGCGCAGCAGTTGAGTCGCTCAATGTGGCGGCGGTGGCGGTGCCACTACTGCTTGAGCGGCGACG
AGCCACAATGACCTTCTCCACGCAGTAG

Upstream 100 bases:

>100_bases
CTTGATATTGATGGTGAACAGCTTGTCCTGAATGAAGGATTGAAGGTGCGTCAGCAAGCAACATTCTGAGGTTCTGTAGA
TCGGAGTTCATGCCTCGCTA

Downstream 100 bases:

>100_bases
TTCGGGTGAGCGAAGCCAGTTTCGACTTCGATGTGATCGTGATCGGTGCGGGTTACGGCGGTTTTGATGCCGCCAAGCAT
GCCGCTGATGATGGCCTCAA

Product: tRNA/rRNA methyltransferase (SpoU)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MISSRRNPLVRRLKFLASSEGRQEQALLLLEGTHLLQEVLRTTHRPKEIVATNFWLERHGDLVQALPAETLIHQVTPSVL
EASLTTVSPDGVASLVPLDSLPQAVNQAKFVLALDRLQDPGNLGTLLRTALAAEVEAVWLASGADPLSPKVLRASAGAIL
QLPYQRFGSSGQEAVEQLAEQLEWAASHGLQVVATMVPGSSAAHSCLPYWQLDWRKPTVLVLGNEGSGLHPRLQACCTDC
VTLPHSAAVESLNVAAVAVPLLLERRRATMTFSTQ

Sequences:

>Translated_275_residues
MISSRRNPLVRRLKFLASSEGRQEQALLLLEGTHLLQEVLRTTHRPKEIVATNFWLERHGDLVQALPAETLIHQVTPSVL
EASLTTVSPDGVASLVPLDSLPQAVNQAKFVLALDRLQDPGNLGTLLRTALAAEVEAVWLASGADPLSPKVLRASAGAIL
QLPYQRFGSSGQEAVEQLAEQLEWAASHGLQVVATMVPGSSAAHSCLPYWQLDWRKPTVLVLGNEGSGLHPRLQACCTDC
VTLPHSAAVESLNVAAVAVPLLLERRRATMTFSTQ
>Mature_275_residues
MISSRRNPLVRRLKFLASSEGRQEQALLLLEGTHLLQEVLRTTHRPKEIVATNFWLERHGDLVQALPAETLIHQVTPSVL
EASLTTVSPDGVASLVPLDSLPQAVNQAKFVLALDRLQDPGNLGTLLRTALAAEVEAVWLASGADPLSPKVLRASAGAIL
QLPYQRFGSSGQEAVEQLAEQLEWAASHGLQVVATMVPGSSAAHSCLPYWQLDWRKPTVLVLGNEGSGLHPRLQACCTDC
VTLPHSAAVESLNVAAVAVPLLLERRRATMTFSTQ

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=158, Percent_Identity=37.3417721518987, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29699; Mature: 29699

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSRRNPLVRRLKFLASSEGRQEQALLLLEGTHLLQEVLRTTHRPKEIVATNFWLERHG
CCCCCCCHHHHHHHHHHCCCCCCHHEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
DLVQALPAETLIHQVTPSVLEASLTTVSPDGVASLVPLDSLPQAVNQAKFVLALDRLQDP
HHHHHCCHHHHHHHHCHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCC
GNLGTLLRTALAAEVEAVWLASGADPLSPKVLRASAGAILQLPYQRFGSSGQEAVEQLAE
CHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCEEECCHHHCCCCHHHHHHHHHH
QLEWAASHGLQVVATMVPGSSAAHSCLPYWQLDWRKPTVLVLGNEGSGLHPRLQACCTDC
HHHHHHHCCCEEEEEECCCCCCHHHCCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHH
VTLPHSAAVESLNVAAVAVPLLLERRRATMTFSTQ
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCC
>Mature Secondary Structure
MISSRRNPLVRRLKFLASSEGRQEQALLLLEGTHLLQEVLRTTHRPKEIVATNFWLERHG
CCCCCCCHHHHHHHHHHCCCCCCHHEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
DLVQALPAETLIHQVTPSVLEASLTTVSPDGVASLVPLDSLPQAVNQAKFVLALDRLQDP
HHHHHCCHHHHHHHHCHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCC
GNLGTLLRTALAAEVEAVWLASGADPLSPKVLRASAGAILQLPYQRFGSSGQEAVEQLAE
CHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCEEECCHHHCCCCHHHHHHHHHH
QLEWAASHGLQVVATMVPGSSAAHSCLPYWQLDWRKPTVLVLGNEGSGLHPRLQACCTDC
HHHHHHHCCCEEEEEECCCCCCHHHCCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHH
VTLPHSAAVESLNVAAVAVPLLLERRRATMTFSTQ
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]