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The map label for this gene is codA [H]

Identifier: 33862599

GI number: 33862599

Start: 371353

End: 372606

Strand: Direct

Name: codA [H]

Synonym: PMT0326

Alternate gene names: 33862599

Gene position: 371353-372606 (Clockwise)

Preceding gene: 33862598

Following gene: 33862600

Centisome position: 15.4

GC content: 57.02

Gene sequence:

>1254_bases
GTGAGCCAGGAGCGCAAGGGATGCCTAGAGGCTTGGGTGCCGCGTGGTTTGTTGACACGGGAAGTGGATGTCTTATCAGC
ACGGGTCACCGCTGAGGGTCTATGTCCTCTGCGCATTTGTTGGCAGGACGGGCGCCTTTGCTCTTTTGAGCTGATTGATG
CTGATGTTTTATCGCCGAAGCGGCTGCTTTTGCCGAGGTTGGCAGAGCCCCATGCTCACCTCGACAAGGCATTCACCTGG
CTTGATTTTCCCAACCTGCATGGCACCTATGGCGGTGCCATGGTTGCGAACTTTAAGGAGCGTCAAAGCCGCACTTTGAT
TGGGGTGAGGCAGCGTGCTGAGAGATCTCTCAAGCTTGCGTTGAGGCATGGCTTGAGAGCCATGCGCAGTCATGTCGACA
GCCTTGGTCCAGCTACCGATAGCAGCTGGGAGGCTTTGCTGGATTTACAGCGTCAGTGGCAGGAGTGGATGGAGTTGCAA
TGGGTCGCTCTGGTGCCGATTGAGCACTGGAGCACCCGCGAAGGCGATCAGCTAGCGGGTCGGGTCGCAGAGGTAGGAGG
TCTGCTGGGTGGTGTGGTTGTGCCCCCTTTTGATCCGGGGAAGACGCGAGATTCATTGCGGCAGATGCTGCAACTTGCCG
ATCGCTTGGGCTGTGGCATTGACCTTCACATTGATGAGTCGCAAAGCCATCCTGCGGCTGGCTTAAAGCAACTGCTTTTA
GTGCTTGATCGCATGTCAATCACAGTGCCGATCACTTGTAGTCATGCCAGCAGCATGGGGTTGTTGCCGCCGGGAGCAGT
GAGTCGTTTGGCTGATCGGATGGCGCATCATCGACTCAATGTGGTTTCTCTGCCGCTGACCAATGGCTGGTTGTTGTCAA
AGCAACCTCGTCGCACTCCTGTGGAGCGACCTCTGGCACCCATCCATCAACTCCAGCTGGCAGGCGTAACGGTGGCTGTG
GGAGGCGACAACGTTCAAGATCCCTGGTTCCCGGTTGGCAACTTTGACCCTTTGGCATTGATGGCTTTTTCGTTGCCTTT
GGCTCATCTGGCACCTTGGCAGCGCTTAGGGCTTGCTCCTTTCACAACAGCGGCGGCCAGGGTGATGAGCCTATCTTGGG
AGGGAACATTGCAGCCAGGCAGCCCAGCCAACCTGCTGCTTTTGGAGGCTGGCAGCTGGGCTGAGGCCCTAGCTGTTCCA
CCCCGCCGGGAGGTGATTGTTGATGGAAACTGTCTGCAAGACCTAGACCAATAA

Upstream 100 bases:

>100_bases
TGCTCCCTAAGATGCGTCTGCCCTCCTATACCGTGACAACCATTGCGGGCGCTGGGCATTTCTTGACTATTCAGACTCGG
ACGGAACCGGGCAAATTGGA

Downstream 100 bases:

>100_bases
GCGTCTTTCCTCAATCAAGAAAGAGCAGGTGTTTTATTGTTTGAATGTCGAAGTCTTTTGGGTTGCTATTCAACATTATT
GTTTTTTTGATCCTTGTTTT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSQERKGCLEAWVPRGLLTREVDVLSARVTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHAHLDKAFTW
LDFPNLHGTYGGAMVANFKERQSRTLIGVRQRAERSLKLALRHGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQ
WVALVPIEHWSTREGDQLAGRVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLL
VLDRMSITVPITCSHASSMGLLPPGAVSRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQLAGVTVAV
GGDNVQDPWFPVGNFDPLALMAFSLPLAHLAPWQRLGLAPFTTAAARVMSLSWEGTLQPGSPANLLLLEAGSWAEALAVP
PRREVIVDGNCLQDLDQ

Sequences:

>Translated_417_residues
MSQERKGCLEAWVPRGLLTREVDVLSARVTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHAHLDKAFTW
LDFPNLHGTYGGAMVANFKERQSRTLIGVRQRAERSLKLALRHGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQ
WVALVPIEHWSTREGDQLAGRVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLL
VLDRMSITVPITCSHASSMGLLPPGAVSRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQLAGVTVAV
GGDNVQDPWFPVGNFDPLALMAFSLPLAHLAPWQRLGLAPFTTAAARVMSLSWEGTLQPGSPANLLLLEAGSWAEALAVP
PRREVIVDGNCLQDLDQ
>Mature_416_residues
SQERKGCLEAWVPRGLLTREVDVLSARVTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHAHLDKAFTWL
DFPNLHGTYGGAMVANFKERQSRTLIGVRQRAERSLKLALRHGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQW
VALVPIEHWSTREGDQLAGRVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLLV
LDRMSITVPITCSHASSMGLLPPGAVSRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQLAGVTVAVG
GDNVQDPWFPVGNFDPLALMAFSLPLAHLAPWQRLGLAPFTTAAARVMSLSWEGTLQPGSPANLLLLEAGSWAEALAVPP
RREVIVDGNCLQDLDQ

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=406, Percent_Identity=26.8472906403941, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786517, Length=363, Percent_Identity=25.068870523416, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 45908; Mature: 45776

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQERKGCLEAWVPRGLLTREVDVLSARVTAEGLCPLRICWQDGRLCSFELIDADVLSPK
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCH
RLLLPRLAEPHAHLDKAFTWLDFPNLHGTYGGAMVANFKERQSRTLIGVRQRAERSLKLA
HHHHHCCCCCHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRHGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQWVALVPIEHWSTREGDQLAG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHH
RVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLL
HHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
VLDRMSITVPITCSHASSMGLLPPGAVSRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTP
HHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCC
VERPLAPIHQLQLAGVTVAVGGDNVQDPWFPVGNFDPLALMAFSLPLAHLAPWQRLGLAP
CCCCCHHHHHEEECCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCCHHHCCCCH
FTTAAARVMSLSWEGTLQPGSPANLLLLEAGSWAEALAVPPRREVIVDGNCLQDLDQ
HHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCHHHHCCCCCCEEEECCHHHHHHCC
>Mature Secondary Structure 
SQERKGCLEAWVPRGLLTREVDVLSARVTAEGLCPLRICWQDGRLCSFELIDADVLSPK
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCH
RLLLPRLAEPHAHLDKAFTWLDFPNLHGTYGGAMVANFKERQSRTLIGVRQRAERSLKLA
HHHHHCCCCCHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRHGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQWVALVPIEHWSTREGDQLAG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHH
RVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLL
HHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
VLDRMSITVPITCSHASSMGLLPPGAVSRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTP
HHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCC
VERPLAPIHQLQLAGVTVAVGGDNVQDPWFPVGNFDPLALMAFSLPLAHLAPWQRLGLAP
CCCCCHHHHHEEECCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCCHHHCCCCH
FTTAAARVMSLSWEGTLQPGSPANLLLLEAGSWAEALAVPPRREVIVDGNCLQDLDQ
HHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCHHHHCCCCCCEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]