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The map label for this gene is 33862568

Identifier: 33862568

GI number: 33862568

Start: 334288

End: 336471

Strand: Direct

Name: 33862568

Synonym: PMT0295

Alternate gene names: NA

Gene position: 334288-336471 (Clockwise)

Preceding gene: 33862565

Following gene: 33862569

Centisome position: 13.87

GC content: 38.23

Gene sequence:

>2184_bases
ATGTCCCGTCGTCGTACTGGTGCCATTGCGATAGGGGTTGGTGCTCTTACTGCTGTTGTGTTGTCTCTAGTAGGAGCAAA
GACACCAGTGGTTATTGGGAGTGCTGCTGCCTTAGGAGTCGCTGGTGGGGTTGTTGCTGGTCGTAAGGGGATTGGAAAGA
GTGCTGATGAATTGATGGAAAGCGGAAAATCAAAGTTAGAAAATAAGGATTTTCATGGGGCGATTGATGATTTCAATAAG
TTATTAGATAGTCACCCTTACAATGCTGATTCATATTATAATCGTGGACTTGCTAAAGCAAAATTAGGCAATAATCAAGG
AGCAATTGAAGATTACAGCAAAGCAATTGAAATAAATCCTTTACATGCTATTGCGTATACAAAAAGAGGTAATGCTAAGT
TTGACTTAAAGGATCATCAAGGAGCACTTATTGACTGCAGCAAAGCAATTGAAATAGATGACAATAATGCTGAATTCTTC
TTTAATCGAGGATTCCCAAAGTTGAAGTTGGAAGATCAAGAAGGGACCAAATCGGACTGGTTTAAAGCAGCAGCATTAGG
AGATAAGCATGCAAGTATTTGTTTGAGAGATTTATTTTATAGTCACTCTCAAAGTATGATAGATGCTCAATCTGATGACC
TAACAGAAGTTGAAAGGCACTCAAGGCGGTGCCTTCTCCTAGAGGATTTTGATCCTCTGGAGGCAATTGATGGATACTTA
ACACTACTAAGTATCGAACCTTCTAATGCCGAACACTATATCTCTATCGGCAAGTTAAAAAGGAGAATAGGAGACAATGA
AGGGGCGTTGATTGATTTAAGCACGGCGATTGAACTTGACCCGAAGAGTTCTACTGCTTATGGAGAGCGTGGTCTTGTAA
AGAGCATAATGGAAGACTATATGGGAGCAATTAATGACTATAATCATTGCTTATGTGTTAAAAGAGAGAAAGTGCTTGAG
AAGCGTTATCAAACTTTTATCAAGAGATTACTGGGTGATCTTTTAAGGCAAAATACAGATATCAATCCAAAGGATTCGCT
TAACTATACTTATCGTGCTGCGAGTAAATGTAGTGAAGGTGATTATCAAGGCGCTATAGAAGATTATACTAAAGCACTAG
AATTAGACAGTAAGAACTCTTTGGCATATATGTTCAGAGGTGCTTGCCATGATTTAAGTGGAGATTCAAAAGCAGCGCTT
GATGATTATTCAGAATCCATAGAACTGAATCCCTCTAATGCAGATATCTATTACACCCGTGGAGTTACATTAAGGGACTC
CGGTGATGATATAGGTGCACTTTCAGATTTTACCCTAACTATTAAATTAGACAGATGGAATGCATTAGCATATAGGAATC
GAGGGAATCTCCACTTTAGACATTCAGAATTAAAAAGTGCTTGTTGCGATTGGAATGAAGCGTCAGACTTAGGAGATGAA
ATAGCAAAAGGGTTATTAGAAGAGCATTGTGACTCTTGTGAATTGCAAACCACTTCATATCAATTTGCCAAACTAGGAGA
TGAAAATTTTGATGATGATTATGCTTCTGCAATAGATGCTTACAGTAAGGCATTGGAAATTAACCCCAATGTTGAGATTT
ATCTTATGCGTGCTGCTGCAAAAGTTGAATTAGAAGATCTTGAAGGAGCAATGTATGATTATGAGAAGGCATTGGAAATT
AATCCATACTGTCACGATGCATATTTCTATCGTGGAATTAGCAAAGAAGATTTAGGAGATTATCCTGGGGCAATTGATGA
TTTTACCAAGGCAATAGACATCTCTCCTGATATACGTAGTTACATGAATCGTGCCTCTCTTAAATCAGATCTTGGTGATT
ACCAAGGGGCAATTTCTGATTATACGAAAGTATTAGAAATTGACCCTTATGAAGATGAAATACGTTTCATCGTAGGTGCA
TATAATCGCCGTGGAGAAGCAAAAGCAAGGATTAATGATAGAGAAGGAGCATTAGAGGATTTTACTGAATCTATTGAAAT
CGACCCAGAGAACATATATGCCTATATAAATCGAATATTAGTTAAAAAAGAACTAGGAGACCTCAATGGAGCATGTGAGG
ACTGGAAGAAAGCAGCAGAACTTGGCAATCAATATCCATATATGAAGGTGCGGTTGGAAAACAATAAAGAAGTAACCAAG
TTTGTGACGGAGCACTGTCAGTGA

Upstream 100 bases:

>100_bases
TCCGATGCGGGTGCCCTTCTTCATGTCATGCAGTTGCTGCCCTAATGGTGAGACTGTTTGCTCTACCTAGTCTGAAGACA
TCGGAGTACGCCACCACTTG

Downstream 100 bases:

>100_bases
CCTAGGCGTTGCTTCAGAGGGGTCGCTAACGGGCAAGAAGTCTTTCCCCACCTAGTCTGAAGGCATCGGAGTACGCCACC
TCTTGATGTCTCGCCGTCGT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MSRRRTGAIAIGVGALTAVVLSLVGAKTPVVIGSAAALGVAGGVVAGRKGIGKSADELMESGKSKLENKDFHGAIDDFNK
LLDSHPYNADSYYNRGLAKAKLGNNQGAIEDYSKAIEINPLHAIAYTKRGNAKFDLKDHQGALIDCSKAIEIDDNNAEFF
FNRGFPKLKLEDQEGTKSDWFKAAALGDKHASICLRDLFYSHSQSMIDAQSDDLTEVERHSRRCLLLEDFDPLEAIDGYL
TLLSIEPSNAEHYISIGKLKRRIGDNEGALIDLSTAIELDPKSSTAYGERGLVKSIMEDYMGAINDYNHCLCVKREKVLE
KRYQTFIKRLLGDLLRQNTDINPKDSLNYTYRAASKCSEGDYQGAIEDYTKALELDSKNSLAYMFRGACHDLSGDSKAAL
DDYSESIELNPSNADIYYTRGVTLRDSGDDIGALSDFTLTIKLDRWNALAYRNRGNLHFRHSELKSACCDWNEASDLGDE
IAKGLLEEHCDSCELQTTSYQFAKLGDENFDDDYASAIDAYSKALEINPNVEIYLMRAAAKVELEDLEGAMYDYEKALEI
NPYCHDAYFYRGISKEDLGDYPGAIDDFTKAIDISPDIRSYMNRASLKSDLGDYQGAISDYTKVLEIDPYEDEIRFIVGA
YNRRGEAKARINDREGALEDFTESIEIDPENIYAYINRILVKKELGDLNGACEDWKKAAELGNQYPYMKVRLENNKEVTK
FVTEHCQ

Sequences:

>Translated_727_residues
MSRRRTGAIAIGVGALTAVVLSLVGAKTPVVIGSAAALGVAGGVVAGRKGIGKSADELMESGKSKLENKDFHGAIDDFNK
LLDSHPYNADSYYNRGLAKAKLGNNQGAIEDYSKAIEINPLHAIAYTKRGNAKFDLKDHQGALIDCSKAIEIDDNNAEFF
FNRGFPKLKLEDQEGTKSDWFKAAALGDKHASICLRDLFYSHSQSMIDAQSDDLTEVERHSRRCLLLEDFDPLEAIDGYL
TLLSIEPSNAEHYISIGKLKRRIGDNEGALIDLSTAIELDPKSSTAYGERGLVKSIMEDYMGAINDYNHCLCVKREKVLE
KRYQTFIKRLLGDLLRQNTDINPKDSLNYTYRAASKCSEGDYQGAIEDYTKALELDSKNSLAYMFRGACHDLSGDSKAAL
DDYSESIELNPSNADIYYTRGVTLRDSGDDIGALSDFTLTIKLDRWNALAYRNRGNLHFRHSELKSACCDWNEASDLGDE
IAKGLLEEHCDSCELQTTSYQFAKLGDENFDDDYASAIDAYSKALEINPNVEIYLMRAAAKVELEDLEGAMYDYEKALEI
NPYCHDAYFYRGISKEDLGDYPGAIDDFTKAIDISPDIRSYMNRASLKSDLGDYQGAISDYTKVLEIDPYEDEIRFIVGA
YNRRGEAKARINDREGALEDFTESIEIDPENIYAYINRILVKKELGDLNGACEDWKKAAELGNQYPYMKVRLENNKEVTK
FVTEHCQ
>Mature_726_residues
SRRRTGAIAIGVGALTAVVLSLVGAKTPVVIGSAAALGVAGGVVAGRKGIGKSADELMESGKSKLENKDFHGAIDDFNKL
LDSHPYNADSYYNRGLAKAKLGNNQGAIEDYSKAIEINPLHAIAYTKRGNAKFDLKDHQGALIDCSKAIEIDDNNAEFFF
NRGFPKLKLEDQEGTKSDWFKAAALGDKHASICLRDLFYSHSQSMIDAQSDDLTEVERHSRRCLLLEDFDPLEAIDGYLT
LLSIEPSNAEHYISIGKLKRRIGDNEGALIDLSTAIELDPKSSTAYGERGLVKSIMEDYMGAINDYNHCLCVKREKVLEK
RYQTFIKRLLGDLLRQNTDINPKDSLNYTYRAASKCSEGDYQGAIEDYTKALELDSKNSLAYMFRGACHDLSGDSKAALD
DYSESIELNPSNADIYYTRGVTLRDSGDDIGALSDFTLTIKLDRWNALAYRNRGNLHFRHSELKSACCDWNEASDLGDEI
AKGLLEEHCDSCELQTTSYQFAKLGDENFDDDYASAIDAYSKALEINPNVEIYLMRAAAKVELEDLEGAMYDYEKALEIN
PYCHDAYFYRGISKEDLGDYPGAIDDFTKAIDISPDIRSYMNRASLKSDLGDYQGAISDYTKVLEIDPYEDEIRFIVGAY
NRRGEAKARINDREGALEDFTESIEIDPENIYAYINRILVKKELGDLNGACEDWKKAAELGNQYPYMKVRLENNKEVTKF
VTEHCQ

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310123097, Length=399, Percent_Identity=25.31328320802, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI310110582, Length=516, Percent_Identity=23.6434108527132, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI310131789, Length=516, Percent_Identity=23.6434108527132, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI32307148, Length=471, Percent_Identity=24.416135881104, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI32307150, Length=471, Percent_Identity=24.416135881104, Blast_Score=75, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115532690, Length=411, Percent_Identity=21.8978102189781, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=411, Percent_Identity=21.8978102189781, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17647755, Length=281, Percent_Identity=24.1992882562278, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24585827, Length=281, Percent_Identity=24.1992882562278, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24585829, Length=281, Percent_Identity=24.1992882562278, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 81205; Mature: 81074

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRTGAIAIGVGALTAVVLSLVGAKTPVVIGSAAALGVAGGVVAGRKGIGKSADELME
CCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEECHHHHHHHCCHHHCCCCCCCCHHHHHH
SGKSKLENKDFHGAIDDFNKLLDSHPYNADSYYNRGLAKAKLGNNQGAIEDYSKAIEINP
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHEEECCC
LHAIAYTKRGNAKFDLKDHQGALIDCSKAIEIDDNNAEFFFNRGFPKLKLEDQEGTKSDW
EEEEEEEECCCCEEEECCCCCCEEECCCEEEECCCCCEEEEECCCCCEEEECCCCCHHHH
FKAAALGDKHASICLRDLFYSHSQSMIDAQSDDLTEVERHSRRCLLLEDFDPLEAIDGYL
HHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCEEEEECCCHHHHHCCEE
TLLSIEPSNAEHYISIGKLKRRIGDNEGALIDLSTAIELDPKSSTAYGERGLVKSIMEDY
EEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
MGAINDYNHCLCVKREKVLEKRYQTFIKRLLGDLLRQNTDINPKDSLNYTYRAASKCSEG
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCCC
DYQGAIEDYTKALELDSKNSLAYMFRGACHDLSGDSKAALDDYSESIELNPSNADIYYTR
CCCCHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCHHHHHCCCCEEECCCCCEEEEEC
GVTLRDSGDDIGALSDFTLTIKLDRWNALAYRNRGNLHFRHSELKSACCDWNEASDLGDE
CEEEECCCCCCCCCCCEEEEEEEECCCEEEEECCCCEEEEHHHHHHHHCCCCCHHHHHHH
IAKGLLEEHCDSCELQTTSYQFAKLGDENFDDDYASAIDAYSKALEINPNVEIYLMRAAA
HHHHHHHHCCCCCCEECCCCHHHHCCCCCCCHHHHHHHHHHHHHEECCCCEEEEEEEECC
KVELEDLEGAMYDYEKALEINPYCHDAYFYRGISKEDLGDYPGAIDDFTKAIDISPDIRS
EEEHHHHCCHHHHHHHHEECCCCCCCHHHHCCCCHHHCCCCCCCHHHHHHHCCCCHHHHH
YMNRASLKSDLGDYQGAISDYTKVLEIDPYEDEIRFIVGAYNRRGEAKARINDREGALED
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHEEEEECCCCCCCCCEEECCCCCHHHH
FTESIEIDPENIYAYINRILVKKELGDLNGACEDWKKAAELGNQYPYMKVRLENNKEVTK
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
FVTEHCQ
HHHHHCC
>Mature Secondary Structure 
SRRRTGAIAIGVGALTAVVLSLVGAKTPVVIGSAAALGVAGGVVAGRKGIGKSADELME
CCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEECHHHHHHHCCHHHCCCCCCCCHHHHHH
SGKSKLENKDFHGAIDDFNKLLDSHPYNADSYYNRGLAKAKLGNNQGAIEDYSKAIEINP
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHEEECCC
LHAIAYTKRGNAKFDLKDHQGALIDCSKAIEIDDNNAEFFFNRGFPKLKLEDQEGTKSDW
EEEEEEEECCCCEEEECCCCCCEEECCCEEEECCCCCEEEEECCCCCEEEECCCCCHHHH
FKAAALGDKHASICLRDLFYSHSQSMIDAQSDDLTEVERHSRRCLLLEDFDPLEAIDGYL
HHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCEEEEECCCHHHHHCCEE
TLLSIEPSNAEHYISIGKLKRRIGDNEGALIDLSTAIELDPKSSTAYGERGLVKSIMEDY
EEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
MGAINDYNHCLCVKREKVLEKRYQTFIKRLLGDLLRQNTDINPKDSLNYTYRAASKCSEG
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCCC
DYQGAIEDYTKALELDSKNSLAYMFRGACHDLSGDSKAALDDYSESIELNPSNADIYYTR
CCCCHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCHHHHHCCCCEEECCCCCEEEEEC
GVTLRDSGDDIGALSDFTLTIKLDRWNALAYRNRGNLHFRHSELKSACCDWNEASDLGDE
CEEEECCCCCCCCCCCEEEEEEEECCCEEEEECCCCEEEEHHHHHHHHCCCCCHHHHHHH
IAKGLLEEHCDSCELQTTSYQFAKLGDENFDDDYASAIDAYSKALEINPNVEIYLMRAAA
HHHHHHHHCCCCCCEECCCCHHHHCCCCCCCHHHHHHHHHHHHHEECCCCEEEEEEEECC
KVELEDLEGAMYDYEKALEINPYCHDAYFYRGISKEDLGDYPGAIDDFTKAIDISPDIRS
EEEHHHHCCHHHHHHHHEECCCCCCCHHHHCCCCHHHCCCCCCCHHHHHHHCCCCHHHHH
YMNRASLKSDLGDYQGAISDYTKVLEIDPYEDEIRFIVGAYNRRGEAKARINDREGALED
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHEEEEECCCCCCCCCEEECCCCCHHHH
FTESIEIDPENIYAYINRILVKKELGDLNGACEDWKKAAELGNQYPYMKVRLENNKEVTK
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
FVTEHCQ
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]