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The map label for this gene is aroK [H]

Identifier: 33862436

GI number: 33862436

Start: 187847

End: 188425

Strand: Reverse

Name: aroK [H]

Synonym: PMT0163

Alternate gene names: 33862436

Gene position: 188425-187847 (Counterclockwise)

Preceding gene: 33862440

Following gene: 33862435

Centisome position: 7.82

GC content: 51.3

Gene sequence:

>579_bases
ATGAACGAAAGCCCAGCCCCTCACCCCCTCAAGCAAAGGCTTGGTGGTCGCAACCTCTATTTGGTGGGAATGATGGCCAG
TGGCAAGAGCAGCACAGGCAGGCCTCTAGCCGAACAACTCAGCTATGGGTTTGTTGATACAGATGCCGTCATCGAACAAC
TTGCTGGCCAACCAATCCCGAAGATCTTTAGCGAAGAAGGAGAAGCAGGGTTTCGAACAATGGAGTCTCAAGTACTCAAT
GCCATTGGCCAACGCCATTCACTTGTTGTTGCTACTGGCGGAGGGATAGTGAGTAAGCCAGAAAACTGGGGGGTCTTGCA
TCAGGGCATCGTGATCTGGCTAAACCCTGGGCGAGAAGAGCTACTCAGACGCTTAAATGCCGACAGCGGCAATAGGCCTT
TACTGCAAACAGAAGATCCAGAAGCAGCCTTCGACTGTTTATTTGCCGAGCGCCTACCGCTTTATTGCGAAGCAGACTTG
CATGTGGAAGTGGGAGCAGAGGAACCAGACGGGATTGCGCTAAAGATTATTGAGTTCCTGCCCCAGTTATTATCGCCACC
TCCACAAATGAATGGTTAA

Upstream 100 bases:

>100_bases
ACAGCCGCGGCCATGACCATGGCGTTCCAAATCGGGGACGTCAGTCATCGCTCTCTCTGCCTAGAAGTCATCCTAGAGAT
CTATAGACATTTGCGAACCA

Downstream 100 bases:

>100_bases
AGCAACTATTTTGACAATACTGAAAGAATAGAATATTTAAGTACGGAGGGTTGGTCTGATAGCTAATCCCAATCAAAACA
GACGATCCATCCTCAACTTG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNESPAPHPLKQRLGGRNLYLVGMMASGKSSTGRPLAEQLSYGFVDTDAVIEQLAGQPIPKIFSEEGEAGFRTMESQVLN
AIGQRHSLVVATGGGIVSKPENWGVLHQGIVIWLNPGREELLRRLNADSGNRPLLQTEDPEAAFDCLFAERLPLYCEADL
HVEVGAEEPDGIALKIIEFLPQLLSPPPQMNG

Sequences:

>Translated_192_residues
MNESPAPHPLKQRLGGRNLYLVGMMASGKSSTGRPLAEQLSYGFVDTDAVIEQLAGQPIPKIFSEEGEAGFRTMESQVLN
AIGQRHSLVVATGGGIVSKPENWGVLHQGIVIWLNPGREELLRRLNADSGNRPLLQTEDPEAAFDCLFAERLPLYCEADL
HVEVGAEEPDGIALKIIEFLPQLLSPPPQMNG
>Mature_192_residues
MNESPAPHPLKQRLGGRNLYLVGMMASGKSSTGRPLAEQLSYGFVDTDAVIEQLAGQPIPKIFSEEGEAGFRTMESQVLN
AIGQRHSLVVATGGGIVSKPENWGVLHQGIVIWLNPGREELLRRLNADSGNRPLLQTEDPEAAFDCLFAERLPLYCEADL
HVEVGAEEPDGIALKIIEFLPQLLSPPPQMNG

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=167, Percent_Identity=39.5209580838323, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786587, Length=170, Percent_Identity=31.1764705882353, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20863; Mature: 20863

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESPAPHPLKQRLGGRNLYLVGMMASGKSSTGRPLAEQLSYGFVDTDAVIEQLAGQPIP
CCCCCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCH
KIFSEEGEAGFRTMESQVLNAIGQRHSLVVATGGGIVSKPENWGVLHQGIVIWLNPGREE
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECCCHHH
LLRRLNADSGNRPLLQTEDPEAAFDCLFAERLPLYCEADLHVEVGAEEPDGIALKIIEFL
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCEEEEECCCCCCCHHHHHHHHH
PQLLSPPPQMNG
HHHHCCCCCCCC
>Mature Secondary Structure
MNESPAPHPLKQRLGGRNLYLVGMMASGKSSTGRPLAEQLSYGFVDTDAVIEQLAGQPIP
CCCCCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCH
KIFSEEGEAGFRTMESQVLNAIGQRHSLVVATGGGIVSKPENWGVLHQGIVIWLNPGREE
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECCCHHH
LLRRLNADSGNRPLLQTEDPEAAFDCLFAERLPLYCEADLHVEVGAEEPDGIALKIIEFL
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCEEEEECCCCCCCHHHHHHHHH
PQLLSPPPQMNG
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA