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The map label for this gene is pilC [H]

Identifier: 33862291

GI number: 33862291

Start: 20646

End: 21926

Strand: Reverse

Name: pilC [H]

Synonym: PMT0018

Alternate gene names: 33862291

Gene position: 21926-20646 (Counterclockwise)

Preceding gene: 33862292

Following gene: 33862288

Centisome position: 0.91

GC content: 48.4

Gene sequence:

>1281_bases
ATGACATCCTTCGTCGCCACCTACGAATCCGCAAGTGGTCAAACACGCACAATAACCATCAAAGCGGCCGACCTAACAAC
CGCAAAAAAATTACTACGTCGTCGTGGAATACGAGCAACTGACCTGAAAGCAGCGCTCAGCAATAAAGGACAAGAAAGTA
GCAAAAAAATTGACCGCCAAAAGAATACAAAATCATCAAATCTTGGACTATTTTCCATCGATCTAAGTGCCGCTTTCGAA
AAGTCCCCAGGTGTAAAAGACAAAGCAGTTTTCGCAAGCAAATTGGCAACTCTGGTGGATGCAGGCGTTCCGATCGTGCG
CAGTCTCGACCTAATGGCTAGTCAGCAGCACTTGCCTATGTTCAAACGTGCACTGATGAAGGTGAGTCTTGATGTAAATG
AAGGCAGTGCCATGGGCACTGCTATGAGCAAGTGGCCAAAGGTATTCGACCAACTCAGTATCGCAATGGTGGAAGCCGGA
GAAGCTGGTGGTGTTTTGGATGAATCTCTCAAGAGACTCGCCAAGTTATTAGAAGACAATGCCCGACTCAAGAACCAAAT
CAAAGGGGCCCTTGGTTACCCAATCACTGTGCTGGTGATAGCCATCCTCGTCTTCCTAGGCATGACAATCTTCTTGATCC
CGACCTTTGCAGAAATCTTTGAAGATTTAGGCGCCGAACTGCCCCTGTTCACTCAGTTCATGGTCGACCTAAGCAAATTA
TTGCGTTCCTCCTTTTCCCTGCTATTAACAGGTGTCCTACTGGCGTGCGCTTGGATTTTCAACCGCTACTACTCCACTCA
CCAAGGACGCCGTCAGATCGATCGACTGAAACTGAGAATCCCCCTATTCGGCACTCTGATCATCAAAACTGCCACCGCTC
AATTCTGCAGAATCTTCAGCTCATTGATCAAAGCAGGCGTACCAATCCTGATGTCACTAGAAATTGCCAGCGAAACCGCT
GGCAATGCGATCATTTCCGACGCCATTCTTGAATCACGCACCCTTGTTCAAGAAGGAGTGCTCCTTAGTGCTGCCTTAAT
TCGCCAAAAAGTGCTTCCAGACATGGCCTTAAACATGCTGGCCATTGGCGAGGAAACCGGAGAGATGGATCAAATGCTCA
GCAAGGTGGCTGATTTTTACGAGGATGAGGTCTCTTCCTCGGTGAAGACTCTGACCTCAATGCTTGAACCCGCGATGATC
GTTGTAGTGGGTGTCATCGTGGGCTCCATCCTGCTAGCGATGTATCTCCCGATGTTCACCGTGTTTGATCAGATCCAGTA
G

Upstream 100 bases:

>100_bases
AAACAGGGTGAAATTAGCCGCTCTGAAGCCATCGCCAAAGCCAGTAAACCCAGCGAACTGGAGCAACTCCTCAACGATGG
CTAAGAGACAGGCCTAAGCG

Downstream 100 bases:

>100_bases
CGAACTGCAAACTCTTTGCAATGGCCTGACCAGCAAGCCAACCACTGGTCCAACAATGCTGGAAGTTGAACCCCCCCGTC
AGCCCATCCACATCGAGAAG

Product: pili biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTSFVATYESASGQTRTITIKAADLTTAKKLLRRRGIRATDLKAALSNKGQESSKKIDRQKNTKSSNLGLFSIDLSAAFE
KSPGVKDKAVFASKLATLVDAGVPIVRSLDLMASQQHLPMFKRALMKVSLDVNEGSAMGTAMSKWPKVFDQLSIAMVEAG
EAGGVLDESLKRLAKLLEDNARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKL
LRSSFSLLLTGVLLACAWIFNRYYSTHQGRRQIDRLKLRIPLFGTLIIKTATAQFCRIFSSLIKAGVPILMSLEIASETA
GNAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNMLAIGEETGEMDQMLSKVADFYEDEVSSSVKTLTSMLEPAMI
VVVGVIVGSILLAMYLPMFTVFDQIQ

Sequences:

>Translated_426_residues
MTSFVATYESASGQTRTITIKAADLTTAKKLLRRRGIRATDLKAALSNKGQESSKKIDRQKNTKSSNLGLFSIDLSAAFE
KSPGVKDKAVFASKLATLVDAGVPIVRSLDLMASQQHLPMFKRALMKVSLDVNEGSAMGTAMSKWPKVFDQLSIAMVEAG
EAGGVLDESLKRLAKLLEDNARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKL
LRSSFSLLLTGVLLACAWIFNRYYSTHQGRRQIDRLKLRIPLFGTLIIKTATAQFCRIFSSLIKAGVPILMSLEIASETA
GNAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNMLAIGEETGEMDQMLSKVADFYEDEVSSSVKTLTSMLEPAMI
VVVGVIVGSILLAMYLPMFTVFDQIQ
>Mature_425_residues
TSFVATYESASGQTRTITIKAADLTTAKKLLRRRGIRATDLKAALSNKGQESSKKIDRQKNTKSSNLGLFSIDLSAAFEK
SPGVKDKAVFASKLATLVDAGVPIVRSLDLMASQQHLPMFKRALMKVSLDVNEGSAMGTAMSKWPKVFDQLSIAMVEAGE
AGGVLDESLKRLAKLLEDNARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKLL
RSSFSLLLTGVLLACAWIFNRYYSTHQGRRQIDRLKLRIPLFGTLIIKTATAQFCRIFSSLIKAGVPILMSLEIASETAG
NAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNMLAIGEETGEMDQMLSKVADFYEDEVSSSVKTLTSMLEPAMIV
VVGVIVGSILLAMYLPMFTVFDQIQ

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=396, Percent_Identity=27.020202020202, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786295, Length=341, Percent_Identity=29.9120234604106, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 46473; Mature: 46342

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFVATYESASGQTRTITIKAADLTTAKKLLRRRGIRATDLKAALSNKGQESSKKIDRQ
CCCHHEEHHCCCCCEEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
KNTKSSNLGLFSIDLSAAFEKSPGVKDKAVFASKLATLVDAGVPIVRSLDLMASQQHLPM
HCCCCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
FKRALMKVSLDVNEGSAMGTAMSKWPKVFDQLSIAMVEAGEAGGVLDESLKRLAKLLEDN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ARLKNQIKGALGYPITVLVIAILVFLGMTIFLIPTFAEIFEDLGAELPLFTQFMVDLSKL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LRSSFSLLLTGVLLACAWIFNRYYSTHQGRRQIDRLKLRIPLFGTLIIKTATAQFCRIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SLIKAGVPILMSLEIASETAGNAIISDAILESRTLVQEGVLLSAALIRQKVLPDMALNML
HHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGEETGEMDQMLSKVADFYEDEVSSSVKTLTSMLEPAMIVVVGVIVGSILLAMYLPMFT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFDQIQ
HHHCCC
>Mature Secondary Structure 
TSFVATYESASGQTRTITIKAADLTTAKKLLRRRGIRATDLKAALSNKGQESSKKIDRQ
CCHHEEHHCCCCCEEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH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HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]