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The map label for this gene is msrB

Identifier: 326424140

GI number: 326424140

Start: 3210181

End: 3210645

Strand: Reverse

Name: msrB

Synonym: NA

Alternate gene names: 326424140

Gene position: 3210645-3210181 (Counterclockwise)

Preceding gene: 27366408

Following gene: 27366402

Centisome position: 97.83

GC content: 43.01

Gene sequence:

>465_bases
TTGCACAAAAAGTCGTCAACATTAATAAGAAAAAGGGAAATTAGTGACGTGACAAAAGAAAGTAAAGTTGTGCTCAAGTC
AGACCAGCAATGGCGTGAGCAGTTGTCTGAACAGGAATATCATGTGTGTCGTGAGCAAGGAACCGAACCTCCTTTTAGTG
GCAAGCTACTGCACAATAAAGACAGCGGAGAATATGCATGCACTTGCTGTCATGCGCCGCTGTTTTCTTCTGTTAACAAA
TACGACTCAGGCTGTGGTTGGCCAAGTTTTGATGCGCCGATTAATGAGACGGCTGTCCTGTATTTAGATGATTTTAGTCA
CGGAATGAAGCGAGTAGAGATCCGCTGTGCACGATGCGATAGCCACTTAGGGCACGTTTTTCCTGATGGACCTAAAACAA
CCGGAGAACGTTTTTGTGTCAATTCAGTGTCGTTAATTTTCAACAAAATTGAAACTAATGAGTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: peptide methionine sulfoxide reductase msrB

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:
NA

Sequences:

>Translated_154_residues
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNKDSGEYACTCCHAPLFSSVNK
YDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCDSHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE
>Mature_154_residues
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNKDSGEYACTCCHAPLFSSVNK
YDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCDSHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI37620216, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI301336164, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI301336162, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI73089054, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=49.21875, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788077, Length=128, Percent_Identity=58.59375, Blast_Score=172, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17553450, Length=122, Percent_Identity=48.3606557377049, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=122, Percent_Identity=48.3606557377049, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=131, Percent_Identity=42.7480916030534, Blast_Score=101, Evalue=6e-23,
Organism=Drosophila melanogaster, GI221378664, Length=134, Percent_Identity=44.7761194029851, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24645799, Length=129, Percent_Identity=44.9612403100775, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI45553335, Length=129, Percent_Identity=44.9612403100775, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21356369, Length=129, Percent_Identity=44.9612403100775, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221378662, Length=141, Percent_Identity=42.5531914893617, Blast_Score=119, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24645801, Length=142, Percent_Identity=42.9577464788732, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24645804, Length=142, Percent_Identity=42.9577464788732, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_VIBVU (Q8D849)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_761932.1
- ProteinModelPortal:   Q8D849
- SMR:   Q8D849
- GeneID:   1179968
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_3139
- HOGENOM:   HBG715255
- OMA:   EVRCNHC
- ProtClustDB:   PRK00222
- BioCyc:   VVUL216895:VV1_3139-MONOMER
- BRENDA:   1.8.4.12
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 17501; Mature: 17501

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: ACT_SITE 139-139

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNK
CCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECC
DSGEYACTCCHAPLFSSVNKYDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCD
CCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
SHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNK
CCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECC
DSGEYACTCCHAPLFSSVNKYDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCD
CCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
SHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA