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The map label for this gene is rstB [H]

Identifier: 326423919

GI number: 326423919

Start: 2004310

End: 2005944

Strand: Reverse

Name: rstB [H]

Synonym: NA

Alternate gene names: 326423919

Gene position: 2005944-2004310 (Counterclockwise)

Preceding gene: 326423920

Following gene: 27365349

Centisome position: 61.12

GC content: 48.07

Gene sequence:

>1635_bases
GTGTGCCTCTTCTTGGGAGGTTTCATTATGATTCGCGCATTTGCCATCTTATGGTTGGCGGTGTTTGTACCGACTACTTT
GTTGATCATCCCCAGTGGTGTAAACCCGGTTTTAAAACTCAACGAGCAGTTTTCCGAAGATTTCTATAAGCCGATCTATC
GGGTGAACTTTGAGGTGTTGTCCAACAAACTCTTGCAGCAACCCACGACTCAGTGGCAACAAACGATCGACCACTATGCC
AAAAGCTTTGCCTATCCTGTGAAGCTCCAAACGTTGGCAGATTACCAAGCCGACAAAGCCATCTATGCTTCACTACAACA
AGGCCAAGTAACGTTTCTTTATGCCGACCCAATGGCGCTCTTACAACGAGTTGGTGACAGTGACCAAGTGCTGTATATCG
CTCTTAACGAATCCACCGAGCATGCAGTGCTCAATCAGGCCAAGGGTACACTCTCATTAGCGATTGAAGATCTGCGTCAA
CTGCCTAAAAGTGAGTGGAAAAACACGCTAGCACAAACCAACGCCAAACTCCCTGTCCACATTAGTTTGACCAACGAAAC
GCAACTTAGCGAGACTGCCAAGCTCGCTTTGTTGAACTCCCCCGACGAGATTGTTAGTTATATCAATGATGAGGGACGCG
TCGAGCTGCTTGCCCCCATCGATGATGGCTTGTGGTTACACGTCCAAGATAACTTATCGCAAGCCGTACAACTCAAGTTG
AGCACCACCATCGCGCTGATGTTCTTCCTACTGATTTCGCTTGCTTTGATTTTGTGGGTTTATCCACTTTGGCGTGACTT
AACTCGACTGGTGGCAACCGCCACCGAATTTGGCCAAGGCAAACTGTCACAACGGGCGCGAGCTTCCAAGCTCTCGGTGG
TTTCTCAACTCAGTGACTCCTTCAACAACATGGCCGACAATATCGAGAGTCTCATTGCTCGGCAGCGTGAACTGACCAAC
GCCGTCGCACACGATTTACGTACGCCATTGTATCGGCTGCGCTTTGCGATTGAGATGCTGGAAGATCCTCACACCAGCGA
CGCGCAAAAAGAGAAATATCAACGCGCACTGCACACAAGCATTGATGATCTCGACCATCTCATCAATCAGAATTTACTGC
TCTCTCGCTACAATCGGATTGCCGATATCACCCATTTTTCACCATGTTGCTTTGCTAGGGAGTTGCTCAATGAAATCGAT
GATTTCAAACTTCAGCATCCCGATCTCGATATCCAGTTTTACTGCTCGCCAGAGTTAAAACAGCACCGCATGTTCATCGA
CAACAAAGGATTGATGCGCGCGGTGAAAAACCTTCTTACCAATGCAAGCCGATTTGCTCAAAGTACCATTATTGTCTCGT
TTAAATACAGTGGCAGCGCATTTCACATTACGGTGGAAGACGATGGCCAAGGTGTGCCCAATGAACACGCAGAACGCATT
TTTGAACCTTTCACTCAGCTTGATAACCAAGCACGCAGTAGCGAAAAAGGACATGGGTTAGGATTGGCGATCGTTAAACA
AATCATGCTTTGGCACAAAGGCAACGCGAAAGTGGTGTCATCGACTTTGGGTGGTGCTGCGTTTGAACTGCAGTGGCCTG
AGCTGCATCCGAATACTGCCGAGTCGGAATTGTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:
NA

Sequences:

>Translated_544_residues
MCLFLGGFIMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVLSNKLLQQPTTQWQQTIDHYA
KSFAYPVKLQTLADYQADKAIYASLQQGQVTFLYADPMALLQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQ
LPKSEWKNTLAQTNAKLPVHISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDSFNNMADNIESLIARQRELTN
AVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTSIDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEID
DFKLQHPDLDIQFYCSPELKQHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTAESEL
>Mature_544_residues
MCLFLGGFIMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVLSNKLLQQPTTQWQQTIDHYA
KSFAYPVKLQTLADYQADKAIYASLQQGQVTFLYADPMALLQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQ
LPKSEWKNTLAQTNAKLPVHISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDSFNNMADNIESLIARQRELTN
AVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTSIDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEID
DFKLQHPDLDIQFYCSPELKQHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTAESEL

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=398, Percent_Identity=32.4120603015075, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI1790346, Length=266, Percent_Identity=30.8270676691729, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789808, Length=346, Percent_Identity=28.0346820809249, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=29.4871794871795, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=27.7533039647577, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789403, Length=247, Percent_Identity=27.9352226720648, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=28.3950617283951, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87082128, Length=305, Percent_Identity=24.5901639344262, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61554; Mature: 61554

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLFLGGFIMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVL
CEEEEHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SNKLLQQPTTQWQQTIDHYAKSFAYPVKLQTLADYQADKAIYASLQQGQVTFLYADPMAL
HHHHHHCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
LQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQLPKSEWKNTLAQTNAKLPVH
HHHCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
EEECCCHHHHHHHHEEEECCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCHHHHHHHHH
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FNNMADNIESLIARQRELTNAVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
IDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEIDDFKLQHPDLDIQFYCSPELK
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHH
QHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
HHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHH
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHCCCCEEEEECCCCCCCCC
ESEL
CCCC
>Mature Secondary Structure
MCLFLGGFIMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVL
CEEEEHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SNKLLQQPTTQWQQTIDHYAKSFAYPVKLQTLADYQADKAIYASLQQGQVTFLYADPMAL
HHHHHHCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
LQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQLPKSEWKNTLAQTNAKLPVH
HHHCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
EEECCCHHHHHHHHEEEECCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCHHHHHHHHH
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FNNMADNIESLIARQRELTNAVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
IDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEIDDFKLQHPDLDIQFYCSPELK
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHH
QHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
HHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHH
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHCCCCEEEEECCCCCCCCC
ESEL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]