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The map label for this gene is coaE [H]

Identifier: 326423858

GI number: 326423858

Start: 1589639

End: 1590247

Strand: Reverse

Name: coaE [H]

Synonym: NA

Alternate gene names: 326423858

Gene position: 1590247-1589639 (Counterclockwise)

Preceding gene: 27364987

Following gene: 27364984

Centisome position: 48.46

GC content: 48.28

Gene sequence:

>609_bases
ATGGCTTTAGTGATTGGATTGACTGGTGGTATCGCCAGCGGAAAAACAACGGTGGCCAATCTTTTTCAACAACACTTTGC
TATCGATATCGTCGACGCAGACATTGTCGCTCGTCAGGTAGTTGCCCCCGGAAGTGCGGGACTGGCCGCGATTGTTGACC
ATTTCGGTGCTGATATTCTGACTTGTGAAGGCGAACTCGATCGTGGACAACTTCGTCAGCGTATCTTTGCCCATAGCGAA
GAAAAGCAATGGCTCAACGCGCTACTGCACCCTATGATCCGTCGTAAAATGATCGAGGATCTGGCGCAGGTCTCATCCCC
TTACGCTTTGCTCGTTGTACCGCTGTTGGTAGAAAACCAACTACAGACTCTGTGCGACCGCGTTTTGGTCGTGGATGTTG
AAGAAAAAACACAATTACAGCGAACCATGGATCGTGACAGTGTTGATGAACAACAAGTTCGTGCCATACTCAAGGCTCAG
GCAAGCAGACACGAACGTCTCGCCTTGGCAGACGATGTGATTAAAAATGAGTCAAAAGACCAAGATCTTTTGCAGCAAAT
CACAGATTTACACCAAAAGTACCTAGCCATGAGCAAGCAAAATCGGTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:
NA

Sequences:

>Translated_202_residues
MALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADILTCEGELDRGQLRQRIFAHSE
EKQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQLQTLCDRVLVVDVEEKTQLQRTMDRDSVDEQQVRAILKAQ
ASRHERLALADDVIKNESKDQDLLQQITDLHQKYLAMSKQNR
>Mature_201_residues
ALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADILTCEGELDRGQLRQRIFAHSEE
KQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQLQTLCDRVLVVDVEEKTQLQRTMDRDSVDEQQVRAILKAQA
SRHERLALADDVIKNESKDQDLLQQITDLHQKYLAMSKQNR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=34.1968911917098, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=34.1968911917098, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI110227607, Length=162, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227605, Length=162, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI110227603, Length=162, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI110227601, Length=162, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI205277394, Length=162, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1786292, Length=200, Percent_Identity=53, Blast_Score=211, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17554944, Length=190, Percent_Identity=31.5789473684211, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320402, Length=198, Percent_Identity=37.3737373737374, Blast_Score=125, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24644728, Length=204, Percent_Identity=27.9411764705882, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24658602, Length=188, Percent_Identity=28.7234042553192, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22555; Mature: 22424

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADIL
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEE
TCEGELDRGQLRQRIFAHSEEKQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQ
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQTLCDRVLVVDVEEKTQLQRTMDRDSVDEQQVRAILKAQASRHERLALADDVIKNESKD
HHHHHHHHHEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QDLLQQITDLHQKYLAMSKQNR
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADIL
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEE
TCEGELDRGQLRQRIFAHSEEKQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQ
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQTLCDRVLVVDVEEKTQLQRTMDRDSVDEQQVRAILKAQASRHERLALADDVIKNESKD
HHHHHHHHHEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QDLLQQITDLHQKYLAMSKQNR
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA