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The map label for this gene is dsbC [H]

Identifier: 326423727

GI number: 326423727

Start: 530310

End: 531095

Strand: Reverse

Name: dsbC [H]

Synonym: NA

Alternate gene names: 326423727

Gene position: 531095-530310 (Counterclockwise)

Preceding gene: 27363993

Following gene: 161501843

Centisome position: 16.18

GC content: 49.24

Gene sequence:

>786_bases
ATGAGCGTATTACGCCGATTAACTCTTTTAACTCTTCCTCTCTTTGTGACGGCCTGCGGTGCTGAAGAAAGCCAAGCTGT
CGAAACAGCTCAGCCAGCGGCACAAGTGGCGGCGAGCACGCATTTTGATAGCGAGGCTCTCAAAGCTCGTTTTTCCAAGC
TGGGCCTGAACATCATGGATATTCAACCTTCGGATGTGGCTGGTTTAGTCGAAATTCAAACCAGTGGCGGGGTGTTATTT
GCGTCTAATGACGGTAGCCACTTTATCGCAGGAACCTTGTATGCCATTGACGAAAATGGTCAATACAAGGATGTGATTGC
AGAACGCCAAGCGCCGCTCAACGCCAAGAAAATTGCCGAATTTGCTGACAGCGCGATCGAGTACAAAGCCAAAGATGAAA
AATACGTGGTGACAGTGTTTACCGACATTACTTGTGGTTACTGCGTTCGTCTACACAGCCAGATGCAGGGCTACAATGAC
TTAGGTATCACCGTGCGTTACATGGCATACCCACGCCAAGGTGGCACGGGCCCAGTGGCAGAACAAATGGCGGGCATCTG
GTGTGCCGCTAATCCGCAAGAAGCGATGCATGATGCTAAAGTGAACCGCAAATTTGCCCCAGCGAAAAATGATTTACAAC
AGTGCAAGCAGACCGTGGCTCAACATTACCAACTTGGTCAGCAACTCGGTATTACAGGCACGCCTGCAATTTTCTTGCCA
AATGGTGAACTGGTTGCTGGTTACTTGCCACCAGAAAAACTGCTAGAGCGCTTACAGCAACAATAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: Thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:
NA

Sequences:

>Translated_261_residues
MSVLRRLTLLTLPLFVTACGAEESQAVETAQPAAQVAASTHFDSEALKARFSKLGLNIMDIQPSDVAGLVEIQTSGGVLF
ASNDGSHFIAGTLYAIDENGQYKDVIAERQAPLNAKKIAEFADSAIEYKAKDEKYVVTVFTDITCGYCVRLHSQMQGYND
LGITVRYMAYPRQGGTGPVAEQMAGIWCAANPQEAMHDAKVNRKFAPAKNDLQQCKQTVAQHYQLGQQLGITGTPAIFLP
NGELVAGYLPPEKLLERLQQQ
>Mature_260_residues
SVLRRLTLLTLPLFVTACGAEESQAVETAQPAAQVAASTHFDSEALKARFSKLGLNIMDIQPSDVAGLVEIQTSGGVLFA
SNDGSHFIAGTLYAIDENGQYKDVIAERQAPLNAKKIAEFADSAIEYKAKDEKYVVTVFTDITCGYCVRLHSQMQGYNDL
GITVRYMAYPRQGGTGPVAEQMAGIWCAANPQEAMHDAKVNRKFAPAKNDLQQCKQTVAQHYQLGQQLGITGTPAIFLPN
GELVAGYLPPEKLLERLQQQ

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=225, Percent_Identity=43.1111111111111, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 28384; Mature: 28252

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLRRLTLLTLPLFVTACGAEESQAVETAQPAAQVAASTHFDSEALKARFSKLGLNIMD
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEE
IQPSDVAGLVEIQTSGGVLFASNDGSHFIAGTLYAIDENGQYKDVIAERQAPLNAKKIAE
CCCCCCEEEEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHCCCCCCHHHHHH
FADSAIEYKAKDEKYVVTVFTDITCGYCVRLHSQMQGYNDLGITVRYMAYPRQGGTGPVA
HHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHH
EQMAGIWCAANPQEAMHDAKVNRKFAPAKNDLQQCKQTVAQHYQLGQQLGITGTPAIFLP
HHHCCEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
NGELVAGYLPPEKLLERLQQQ
CCCEEEECCCHHHHHHHHHCC
>Mature Secondary Structure 
SVLRRLTLLTLPLFVTACGAEESQAVETAQPAAQVAASTHFDSEALKARFSKLGLNIMD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEE
IQPSDVAGLVEIQTSGGVLFASNDGSHFIAGTLYAIDENGQYKDVIAERQAPLNAKKIAE
CCCCCCEEEEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHCCCCCCHHHHHH
FADSAIEYKAKDEKYVVTVFTDITCGYCVRLHSQMQGYNDLGITVRYMAYPRQGGTGPVA
HHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHH
EQMAGIWCAANPQEAMHDAKVNRKFAPAKNDLQQCKQTVAQHYQLGQQLGITGTPAIFLP
HHHCCEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
NGELVAGYLPPEKLLERLQQQ
CCCEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]