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The map label for this gene is ispH [H]

Identifier: 326423722

GI number: 326423722

Start: 502725

End: 503687

Strand: Reverse

Name: ispH [H]

Synonym: NA

Alternate gene names: 326423722

Gene position: 503687-502725 (Counterclockwise)

Preceding gene: 326423723

Following gene: 27363964

Centisome position: 15.35

GC content: 49.64

Gene sequence:

>963_bases
ATGAGCAATGAAATGAAAATCTTGTTAGCGAACCCACGTGGATTCTGTGCGGGTGTCGACCGTGCCATCAGTATTGTTGA
GCGTGCACTGGAACTGTATCAACCGCCTATCTACGTACGCCATGAAGTGGTGCACAACCGTTTTGTGGTGGAAGGCTTAA
AGCAGCGCGGCGCGATCTTTGTCGAAGAGTTGCATGAAGTGCCAGACGACAATATTGTTATTTTCTCTGCTCATGGCGTG
TCTCAAGCGGTGCGTCAGGAAGCCAAAGAGCGTGCGCTAACTGTGTTTGATGCGACATGCCCATTGGTGACGAAAGTGCA
TATGGAAGTGGCGAGAGCCAGCCGTAAGCATATGGAAGTGGTGCTGATCGGCCATGCGGGCCACCCAGAGGTAGAAGGCA
CCATGGGTCAATATGCCAGCTTGCAGGGTGGCATGTACCTTGTAGAAAAACCGGAAGATGTACTTGGCTTGAAAGCCATT
GTTAAAGATCCGAGCAACTTGCACTACGTAAGCCAAACGACCTTATCGGTGGATGAAACCGCGGACGTGATTGATGAGTT
GCGTCGAGTTTTCCCAGAGATCCAAGGCCCACGCAAAGACGATATCTGCTATGCGACACAAAACCGCCAGGATGCGGTGC
GTGAATTGGCGAAAGATGTCGACGTGGTAGTGGTAGTTGGTTCAAAGAACTCCTCAAACTCGACCCGACTAAAAGAGTTG
GCGGAAAAACTAGGCACACCTGCTTACTTAACAGATTGTCCGCAAGACATTGAGCCACAATGGTTTGATGGCAAAGTCAA
AGTGGGCGTAACGGCAGGGGCCTCTGCACCAGAAGAACTGGTCAATCAAATCCTAACTCGCATTAAAGAGTTGGGTGCTC
AATCGGTTGAAGAAGTGCTAGGCCGTGAAGAGAACATGTTCTTTGAAGTGCCTAAAGAGCTGCAAATTAAGCAGATTGAC
TAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:
NA

Sequences:

>Translated_320_residues
MSNEMKILLANPRGFCAGVDRAISIVERALELYQPPIYVRHEVVHNRFVVEGLKQRGAIFVEELHEVPDDNIVIFSAHGV
SQAVRQEAKERALTVFDATCPLVTKVHMEVARASRKHMEVVLIGHAGHPEVEGTMGQYASLQGGMYLVEKPEDVLGLKAI
VKDPSNLHYVSQTTLSVDETADVIDELRRVFPEIQGPRKDDICYATQNRQDAVRELAKDVDVVVVVGSKNSSNSTRLKEL
AEKLGTPAYLTDCPQDIEPQWFDGKVKVGVTAGASAPEELVNQILTRIKELGAQSVEEVLGREENMFFEVPKELQIKQID
>Mature_319_residues
SNEMKILLANPRGFCAGVDRAISIVERALELYQPPIYVRHEVVHNRFVVEGLKQRGAIFVEELHEVPDDNIVIFSAHGVS
QAVRQEAKERALTVFDATCPLVTKVHMEVARASRKHMEVVLIGHAGHPEVEGTMGQYASLQGGMYLVEKPEDVLGLKAIV
KDPSNLHYVSQTTLSVDETADVIDELRRVFPEIQGPRKDDICYATQNRQDAVRELAKDVDVVVVVGSKNSSNSTRLKELA
EKLGTPAYLTDCPQDIEPQWFDGKVKVGVTAGASAPEELVNQILTRIKELGAQSVEEVLGREENMFFEVPKELQIKQID

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=318, Percent_Identity=66.3522012578616, Blast_Score=429, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 35576; Mature: 35445

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEMKILLANPRGFCAGVDRAISIVERALELYQPPIYVRHEVVHNRFVVEGLKQRGAIF
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHH
VEELHEVPDDNIVIFSAHGVSQAVRQEAKERALTVFDATCPLVTKVHMEVARASRKHMEV
HHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCEEE
VLIGHAGHPEVEGTMGQYASLQGGMYLVEKPEDVLGLKAIVKDPSNLHYVSQTTLSVDET
EEEECCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECEECHHHH
ADVIDELRRVFPEIQGPRKDDICYATQNRQDAVRELAKDVDVVVVVGSKNSSNSTRLKEL
HHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AEKLGTPAYLTDCPQDIEPQWFDGKVKVGVTAGASAPEELVNQILTRIKELGAQSVEEVL
HHHHCCCCEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHH
GREENMFFEVPKELQIKQID
CCCCCEEEECCCCCCEEECC
>Mature Secondary Structure 
SNEMKILLANPRGFCAGVDRAISIVERALELYQPPIYVRHEVVHNRFVVEGLKQRGAIF
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHH
VEELHEVPDDNIVIFSAHGVSQAVRQEAKERALTVFDATCPLVTKVHMEVARASRKHMEV
HHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCEEE
VLIGHAGHPEVEGTMGQYASLQGGMYLVEKPEDVLGLKAIVKDPSNLHYVSQTTLSVDET
EEEECCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECEECHHHH
ADVIDELRRVFPEIQGPRKDDICYATQNRQDAVRELAKDVDVVVVVGSKNSSNSTRLKEL
HHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AEKLGTPAYLTDCPQDIEPQWFDGKVKVGVTAGASAPEELVNQILTRIKELGAQSVEEVL
HHHHCCCCEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHH
GREENMFFEVPKELQIKQID
CCCCCEEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]