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The map label for this gene is thiL [H]

Identifier: 326423688

GI number: 326423688

Start: 307132

End: 308136

Strand: Reverse

Name: thiL [H]

Synonym: NA

Alternate gene names: 326423688

Gene position: 308136-307132 (Counterclockwise)

Preceding gene: 27363793

Following gene: 27363791

Centisome position: 9.39

GC content: 50.65

Gene sequence:

>1005_bases
ATGCTGGCCTTTTTTATAACAAAGGAAAGGATTTTGATGTCAGGCGAGTTTAATCTGATTGAAAAATACTTCGTTGGCCG
TCAGGCACAACGTAAAGATGTACACCTAGCCGCTGGAGACGACTGCGCGCTAGTTAAGCCACCAAGCAACGTGCAAATTG
CCATTAGCACCGATACCCTAGTATGTGGCACTCATTTCTTAGCCGATGCCGATCCCGCTTGGGTGGCGCATAAGGCGCTA
GCATCGAACATCAGCGATTTGGCGGCCATGGGGGCAACACCTGCGTGGGTCTCATTTGCTCTGACTATGCCGCTAGCCGA
CGAAGCCTGGTTGGCTCCCTTTTGTGATGGTTTTTTTAAGCTGGCGGATTACTTCGGCATACAGCTCATTGGTGGTGACA
CGACGAAAGGTCCACTGAGTTTGACCATGACGGTGCAAGGGTTTGTCCCTGAAGGGAAAGCGATCACGCGCAGTGGTGCC
AAACCGGGCGACTATGTGTTTGTTACGGGGACGCTAGGCGATGCAAAGGCGGGATTGGATGTGATTCTCGATAGCAACTT
GCGTACTCGCCCAGCCGCACAAGCGCTAGAAAAAGCGCACTATATGAGTATGCCGCGGATTTTAGCAGGGCAAGCGTTGG
TCGGATTAGCCTCGGCGGCGATCGATATCTCCGATGGCTTAATTGCGGATTTAGGGCACATCTTAAACCGCTCTCAGGTT
GGTGTTAGCCTGGATGTCTCTAAGCTGCCGATTTCATCTGAACTGCTCTCTTTTTTGACCGAGCGCGAAATGGCACTTCA
ATATGCGCTGACCAGCGGCGAAGAATACGAGCTTTGTTTTACCGTGCCCGAAGAGGCAAGAGGAACAATCGAAAGTGCCT
TGGCACACGTTGGTTGCAAAGTGACGTGTATCGGGCAAATTCGTCCACATGGTTTTTTTGAACTCCATGATGATGGCACA
AAATTAAACTGGGATTTGAGTGGCTTTGACCACTTTAAGGCGTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:
NA

Sequences:

>Translated_334_residues
MLAFFITKERILMSGEFNLIEKYFVGRQAQRKDVHLAAGDDCALVKPPSNVQIAISTDTLVCGTHFLADADPAWVAHKAL
ASNISDLAAMGATPAWVSFALTMPLADEAWLAPFCDGFFKLADYFGIQLIGGDTTKGPLSLTMTVQGFVPEGKAITRSGA
KPGDYVFVTGTLGDAKAGLDVILDSNLRTRPAAQALEKAHYMSMPRILAGQALVGLASAAIDISDGLIADLGHILNRSQV
GVSLDVSKLPISSELLSFLTEREMALQYALTSGEEYELCFTVPEEARGTIESALAHVGCKVTCIGQIRPHGFFELHDDGT
KLNWDLSGFDHFKA
>Mature_334_residues
MLAFFITKERILMSGEFNLIEKYFVGRQAQRKDVHLAAGDDCALVKPPSNVQIAISTDTLVCGTHFLADADPAWVAHKAL
ASNISDLAAMGATPAWVSFALTMPLADEAWLAPFCDGFFKLADYFGIQLIGGDTTKGPLSLTMTVQGFVPEGKAITRSGA
KPGDYVFVTGTLGDAKAGLDVILDSNLRTRPAAQALEKAHYMSMPRILAGQALVGLASAAIDISDGLIADLGHILNRSQV
GVSLDVSKLPISSELLSFLTEREMALQYALTSGEEYELCFTVPEEARGTIESALAHVGCKVTCIGQIRPHGFFELHDDGT
KLNWDLSGFDHFKA

Specific function: Thiamine biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=322, Percent_Identity=54.9689440993789, Blast_Score=333, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35839; Mature: 35839

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00079 MULTICOPPER_OXIDASE1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAFFITKERILMSGEFNLIEKYFVGRQAQRKDVHLAAGDDCALVKPPSNVQIAISTDTL
CEEEEEECCEEEECCCHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCEEEEEECCEE
VCGTHFLADADPAWVAHKALASNISDLAAMGATPAWVSFALTMPLADEAWLAPFCDGFFK
EECCHHCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHEEEEEECCCCCCHHHHHHHHHHHH
LADYFGIQLIGGDTTKGPLSLTMTVQGFVPEGKAITRSGAKPGDYVFVTGTLGDAKAGLD
HHHHCCEEEECCCCCCCCEEEEEEEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCCEE
VILDSNLRTRPAAQALEKAHYMSMPRILAGQALVGLASAAIDISDGLIADLGHILNRSQV
EEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCC
GVSLDVSKLPISSELLSFLTEREMALQYALTSGEEYELCFTVPEEARGTIESALAHVGCK
CEEEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCE
VTCIGQIRPHGFFELHDDGTKLNWDLSGFDHFKA
EEEEECCCCCCEEEECCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MLAFFITKERILMSGEFNLIEKYFVGRQAQRKDVHLAAGDDCALVKPPSNVQIAISTDTL
CEEEEEECCEEEECCCHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCEEEEEECCEE
VCGTHFLADADPAWVAHKALASNISDLAAMGATPAWVSFALTMPLADEAWLAPFCDGFFK
EECCHHCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHEEEEEECCCCCCHHHHHHHHHHHH
LADYFGIQLIGGDTTKGPLSLTMTVQGFVPEGKAITRSGAKPGDYVFVTGTLGDAKAGLD
HHHHCCEEEECCCCCCCCEEEEEEEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCCEE
VILDSNLRTRPAAQALEKAHYMSMPRILAGQALVGLASAAIDISDGLIADLGHILNRSQV
EEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCC
GVSLDVSKLPISSELLSFLTEREMALQYALTSGEEYELCFTVPEEARGTIESALAHVGCK
CEEEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCE
VTCIGQIRPHGFFELHDDGTKLNWDLSGFDHFKA
EEEEECCCCCCEEEECCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]