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The map label for this gene is ttdA

Identifier: 32267291

GI number: 32267291

Start: 1712563

End: 1713408

Strand: Direct

Name: ttdA

Synonym: HH1792

Alternate gene names: 32267291

Gene position: 1712563-1713408 (Clockwise)

Preceding gene: 32267290

Following gene: 32267292

Centisome position: 95.19

GC content: 43.85

Gene sequence:

>846_bases
ATGAGAGAAGTGCGATATGAAGATATTAAATCTGCTGTTGCTAAACTTGCCATTAATGCGTGTTGTATCCAAACGCCCGA
TATTAAACGCGCCTTTAGTGCTGCAAAGGGAAGTGAAAAGTCTGCATTAGGACAAAATATCCTAGATACGCTCATTGAAA
ATGGCAAGATTGCGGAAAGCAATATGATGCCTATCTGCCAAGATACAGGTATGACCGTGGTGTTTGTAGAAATCGGGCAA
GATGTGCATATCACAGGAGGCTACCTTGAAGATGCCATTAATGAGGGTATTAAAGAGGGCTATACGAATGGTTATTTGCG
TAAATCTGTCGTAGAAGAGCCACTCTATGAGCGCAAAAATACGACAAATAACTCTCCTGCAGTCATTCATACGCGAATAA
TCAAGGGCGATAAGTTGCATTTAAAAGTTTGCCCTAAAGGCTTTGGGAGCGAGAATAAAAGTGTGCTTAAAATGCTTGTC
CCAGCCGATGGCATTGAGGGTGTGAAAAAAGTCTTTACCGAAGCGGTGAAACTCGCAGGTCCCAATGCTTGTCCTCCTAT
GGTGATTGGCGTAGGTATTGGTGGGACAATGGAAAAAGCAGCAATTTTAGCCAAACAGGCGGCTGTGCGCGAAATAGATT
CTAAAAATAAAGACCCACGCTATGCCAAGCTCGAAGAAGAATTGCTTGAAATTGCGAATCAAACAGGCGTAGGACCACAA
GGATTAGGTGGCACTACGACTGCGTTTAAAGTCAATGTGGAATGGTATCCTACACACATTGCGGGGCTTCCTGTGGCAGT
AAATATCAACTGCCACGCCGCACGACACGCTGATATTGAGCTTTAA

Upstream 100 bases:

>100_bases
GCTTAGAGTTTGGCTTTGGATTTAATAAATGGCTTTAAGTCTTTTTTACATTATATTAGAGTAGAATGGTGTGTTTTCAA
ACAAAAATAAGGAGGAAGTA

Downstream 100 bases:

>100_bases
GGAGGAAAAAATGGGAGAGCCAAAAAAAATCACTGCACCTATAAGTAAAGAAGTGGCAAAAAGCCTCAAAGCAGGGGAGA
GTGTGCTAATCTCTGGCACA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MREVRYEDIKSAVAKLAINACCIQTPDIKRAFSAAKGSEKSALGQNILDTLIENGKIAESNMMPICQDTGMTVVFVEIGQ
DVHITGGYLEDAINEGIKEGYTNGYLRKSVVEEPLYERKNTTNNSPAVIHTRIIKGDKLHLKVCPKGFGSENKSVLKMLV
PADGIEGVKKVFTEAVKLAGPNACPPMVIGVGIGGTMEKAAILAKQAAVREIDSKNKDPRYAKLEEELLEIANQTGVGPQ
GLGGTTTAFKVNVEWYPTHIAGLPVAVNINCHAARHADIEL

Sequences:

>Translated_281_residues
MREVRYEDIKSAVAKLAINACCIQTPDIKRAFSAAKGSEKSALGQNILDTLIENGKIAESNMMPICQDTGMTVVFVEIGQ
DVHITGGYLEDAINEGIKEGYTNGYLRKSVVEEPLYERKNTTNNSPAVIHTRIIKGDKLHLKVCPKGFGSENKSVLKMLV
PADGIEGVKKVFTEAVKLAGPNACPPMVIGVGIGGTMEKAAILAKQAAVREIDSKNKDPRYAKLEEELLEIANQTGVGPQ
GLGGTTTAFKVNVEWYPTHIAGLPVAVNINCHAARHADIEL
>Mature_281_residues
MREVRYEDIKSAVAKLAINACCIQTPDIKRAFSAAKGSEKSALGQNILDTLIENGKIAESNMMPICQDTGMTVVFVEIGQ
DVHITGGYLEDAINEGIKEGYTNGYLRKSVVEEPLYERKNTTNNSPAVIHTRIIKGDKLHLKVCPKGFGSENKSVLKMLV
PADGIEGVKKVFTEAVKLAGPNACPPMVIGVGIGGTMEKAAILAKQAAVREIDSKNKDPRYAKLEEELLEIANQTGVGPQ
GLGGTTTAFKVNVEWYPTHIAGLPVAVNINCHAARHADIEL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=263, Percent_Identity=33.0798479087452, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790564, Length=236, Percent_Identity=33.0508474576271, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787897, Length=264, Percent_Identity=32.9545454545455, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30253; Mature: 30253

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVRYEDIKSAVAKLAINACCIQTPDIKRAFSAAKGSEKSALGQNILDTLIENGKIAES
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
NMMPICQDTGMTVVFVEIGQDVHITGGYLEDAINEGIKEGYTNGYLRKSVVEEPLYERKN
CCCCEECCCCCEEEEEEECCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
TTNNSPAVIHTRIIKGDKLHLKVCPKGFGSENKSVLKMLVPADGIEGVKKVFTEAVKLAG
CCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHCC
PNACPPMVIGVGIGGTMEKAAILAKQAAVREIDSKNKDPRYAKLEEELLEIANQTGVGPQ
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
GLGGTTTAFKVNVEWYPTHIAGLPVAVNINCHAARHADIEL
CCCCCCEEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MREVRYEDIKSAVAKLAINACCIQTPDIKRAFSAAKGSEKSALGQNILDTLIENGKIAES
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
NMMPICQDTGMTVVFVEIGQDVHITGGYLEDAINEGIKEGYTNGYLRKSVVEEPLYERKN
CCCCEECCCCCEEEEEEECCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
TTNNSPAVIHTRIIKGDKLHLKVCPKGFGSENKSVLKMLVPADGIEGVKKVFTEAVKLAG
CCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHCC
PNACPPMVIGVGIGGTMEKAAILAKQAAVREIDSKNKDPRYAKLEEELLEIANQTGVGPQ
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
GLGGTTTAFKVNVEWYPTHIAGLPVAVNINCHAARHADIEL
CCCCCCEEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]