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The map label for this gene is aspB [H]

Identifier: 32267170

GI number: 32267170

Start: 1598650

End: 1599837

Strand: Direct

Name: aspB [H]

Synonym: HH1671

Alternate gene names: 32267170

Gene position: 1598650-1599837 (Clockwise)

Preceding gene: 32267169

Following gene: 32267171

Centisome position: 88.86

GC content: 37.37

Gene sequence:

>1188_bases
ATGAAAAAGACAACTTATGCAAAACGTGTAGAGCTTTTAGGAGAATCTACCACAATTGCTATTAGCACACTTGCACGAGA
ATTAAAAGCTGCGGGGCAAGATATATTAAGTTTTTCGGCTGGAGAACCTGATTTTGATACGCCAGAAATTATAAAAGATG
AGGCTATTAGAGCGTTAAAAAGTGGTTTTACTAAATATACTGCGGTGGCAGGGATTCCAGAATTACTTGAGGCGATTAAA
GATAAACTTTTGCGTGAAAATACTCTTGCTTATGAGCGTAATGAAATACTTGTAAGCAATGGAGCAAAACACTCACTTTT
TAATGTTTTTCAAGCTCTTGTTGATAAAGATGATGAGGTGATTATCCCCTCTCCTTATTGGGTTACCTATCCTGAACTTG
TAACCTTTAGCGGCGGTAAATCTGTCATTGTGCAAACAACGCAAGCAAATAATTTTAAAATTACACCAAAACAGCTCCGT
GAAGCCATCACACCCAAGACAAAAGTATTTGTGCTTAATACCCCATCTAATCCTACCGGTATGGTTTATACTAAAGAAGA
ACTAGAATCTCTTGCTGAAGTCTTAAAAGACACAAACATATGGGTTGTGAGTGATGAAATGTATGAAAAACTTGTTTATG
GAGTGAAATTTTTCTCTGTTGCAGCTGTAAATGAGGATATGATGCAGCGCACTATCACAATTAATGGACTAAGTAAGTCT
GTGGCGATGACAGGGTGGCGTATAGGCTATCTCGCGTGTAAAGACAAAAAACTTGTTAAATTAATGAACAATCTTCAAAG
CCAATGCACTTCTAATATTAATTCTATCACGCAAAAAGCTGCCATAGTAGCACTTAAAGGAGAGGCAAATAATGATATTG
AGGATATGAGAAAGGCATTTGAAGAGCGTATGCGTTTTGCGTGCGATGCGATTAATAATATTCAAAACCTTAATGTGTGT
GAGCCTCAAGGTGCATTTTATCTCTTTATTAATATTTCTACATTACCTCGGTATGGTACAGATTCTATGGGATTTTGCCA
AGCATTACTTAAGGAGCAAGGAGTAGCACTTGTGCCCGGAGTTGCTTTTGGTATGGAGGGATTTGTGCGACTTTCTTTTG
CGTGTTCTTTAGAGCAGCTTAAAGAAGGCATTACACGCATTTCGCAATTTGTTAAAACGCTTTTTTAA

Upstream 100 bases:

>100_bases
TGATGCGATTGCAAAAGAAATGCGTTTAAGCAAGGGTGAGATTGAATTTACACTCAAACTTGCGGATATTAAAGAGTAAT
CTTAAGCACAAGGAGAAAAG

Downstream 100 bases:

>100_bases
GTAATGAAAATGCGAGATCTCTTTTACACATATTCGAAGCATAGCATATTTGTGTTTTTGCTTTGTTTGTGTGCTTGGTG
GTGTCTTATTAATGATGAGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKKTTYAKRVELLGESTTIAISTLARELKAAGQDILSFSAGEPDFDTPEIIKDEAIRALKSGFTKYTAVAGIPELLEAIK
DKLLRENTLAYERNEILVSNGAKHSLFNVFQALVDKDDEVIIPSPYWVTYPELVTFSGGKSVIVQTTQANNFKITPKQLR
EAITPKTKVFVLNTPSNPTGMVYTKEELESLAEVLKDTNIWVVSDEMYEKLVYGVKFFSVAAVNEDMMQRTITINGLSKS
VAMTGWRIGYLACKDKKLVKLMNNLQSQCTSNINSITQKAAIVALKGEANNDIEDMRKAFEERMRFACDAINNIQNLNVC
EPQGAFYLFINISTLPRYGTDSMGFCQALLKEQGVALVPGVAFGMEGFVRLSFACSLEQLKEGITRISQFVKTLF

Sequences:

>Translated_395_residues
MKKTTYAKRVELLGESTTIAISTLARELKAAGQDILSFSAGEPDFDTPEIIKDEAIRALKSGFTKYTAVAGIPELLEAIK
DKLLRENTLAYERNEILVSNGAKHSLFNVFQALVDKDDEVIIPSPYWVTYPELVTFSGGKSVIVQTTQANNFKITPKQLR
EAITPKTKVFVLNTPSNPTGMVYTKEELESLAEVLKDTNIWVVSDEMYEKLVYGVKFFSVAAVNEDMMQRTITINGLSKS
VAMTGWRIGYLACKDKKLVKLMNNLQSQCTSNINSITQKAAIVALKGEANNDIEDMRKAFEERMRFACDAINNIQNLNVC
EPQGAFYLFINISTLPRYGTDSMGFCQALLKEQGVALVPGVAFGMEGFVRLSFACSLEQLKEGITRISQFVKTLF
>Mature_395_residues
MKKTTYAKRVELLGESTTIAISTLARELKAAGQDILSFSAGEPDFDTPEIIKDEAIRALKSGFTKYTAVAGIPELLEAIK
DKLLRENTLAYERNEILVSNGAKHSLFNVFQALVDKDDEVIIPSPYWVTYPELVTFSGGKSVIVQTTQANNFKITPKQLR
EAITPKTKVFVLNTPSNPTGMVYTKEELESLAEVLKDTNIWVVSDEMYEKLVYGVKFFSVAAVNEDMMQRTITINGLSKS
VAMTGWRIGYLACKDKKLVKLMNNLQSQCTSNINSITQKAAIVALKGEANNDIEDMRKAFEERMRFACDAINNIQNLNVC
EPQGAFYLFINISTLPRYGTDSMGFCQALLKEQGVALVPGVAFGMEGFVRLSFACSLEQLKEGITRISQFVKTLF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=392, Percent_Identity=28.8265306122449, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI169881279, Length=392, Percent_Identity=28.8265306122449, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI56713254, Length=409, Percent_Identity=28.361858190709, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI56713256, Length=409, Percent_Identity=28.361858190709, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI169881281, Length=387, Percent_Identity=25.0645994832041, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4507369, Length=426, Percent_Identity=23.0046948356808, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1786816, Length=388, Percent_Identity=25.7731958762887, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1788627, Length=349, Percent_Identity=28.9398280802292, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=28.8359788359788, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=390, Percent_Identity=28.7179487179487, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17567663, Length=347, Percent_Identity=25.0720461095101, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=390, Percent_Identity=28.7179487179487, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17567369, Length=397, Percent_Identity=28.2115869017632, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71981209, Length=346, Percent_Identity=22.5433526011561, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=332, Percent_Identity=26.2048192771084, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI18859735, Length=312, Percent_Identity=24.6794871794872, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573069, Length=430, Percent_Identity=24.8837209302326, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24646114, Length=430, Percent_Identity=24.8837209302326, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28573067, Length=430, Percent_Identity=24.8837209302326, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28573065, Length=430, Percent_Identity=24.8837209302326, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641770, Length=368, Percent_Identity=26.3586956521739, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641760, Length=368, Percent_Identity=26.3586956521739, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641768, Length=368, Percent_Identity=26.3586956521739, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641766, Length=368, Percent_Identity=26.3586956521739, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641764, Length=368, Percent_Identity=26.3586956521739, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551451, Length=368, Percent_Identity=26.3586956521739, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43937; Mature: 43937

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTTYAKRVELLGESTTIAISTLARELKAAGQDILSFSAGEPDFDTPEIIKDEAIRALK
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHH
SGFTKYTAVAGIPELLEAIKDKLLRENTLAYERNEILVSNGAKHSLFNVFQALVDKDDEV
HCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCEEEEECCCHHHHHHHHHHHHCCCCCE
IIPSPYWVTYPELVTFSGGKSVIVQTTQANNFKITPKQLREAITPKTKVFVLNTPSNPTG
EECCCCEEECCCEEEECCCCEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCC
MVYTKEELESLAEVLKDTNIWVVSDEMYEKLVYGVKFFSVAAVNEDMMQRTITINGLSKS
EEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCHH
VAMTGWRIGYLACKDKKLVKLMNNLQSQCTSNINSITQKAAIVALKGEANNDIEDMRKAF
HHHCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
EERMRFACDAINNIQNLNVCEPQGAFYLFINISTLPRYGTDSMGFCQALLKEQGVALVPG
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEECC
VAFGMEGFVRLSFACSLEQLKEGITRISQFVKTLF
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKKTTYAKRVELLGESTTIAISTLARELKAAGQDILSFSAGEPDFDTPEIIKDEAIRALK
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHH
SGFTKYTAVAGIPELLEAIKDKLLRENTLAYERNEILVSNGAKHSLFNVFQALVDKDDEV
HCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCEEEEECCCHHHHHHHHHHHHCCCCCE
IIPSPYWVTYPELVTFSGGKSVIVQTTQANNFKITPKQLREAITPKTKVFVLNTPSNPTG
EECCCCEEECCCEEEECCCCEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCC
MVYTKEELESLAEVLKDTNIWVVSDEMYEKLVYGVKFFSVAAVNEDMMQRTITINGLSKS
EEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCHH
VAMTGWRIGYLACKDKKLVKLMNNLQSQCTSNINSITQKAAIVALKGEANNDIEDMRKAF
HHHCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
EERMRFACDAINNIQNLNVCEPQGAFYLFINISTLPRYGTDSMGFCQALLKEQGVALVPG
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEECC
VAFGMEGFVRLSFACSLEQLKEGITRISQFVKTLF
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]