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The map label for this gene is qacA [H]

Identifier: 32266963

GI number: 32266963

Start: 1407211

End: 1408713

Strand: Direct

Name: qacA [H]

Synonym: HH1464

Alternate gene names: 32266963

Gene position: 1407211-1408713 (Clockwise)

Preceding gene: 32266961

Following gene: 32266964

Centisome position: 78.22

GC content: 41.18

Gene sequence:

>1503_bases
ATGAATCTCATTCTTTTTACTATTCTACTTGCTGTATTTGTCGTGCCTAGCTCTATTTCTGGCACAGCTATTGCCTTACC
CTATATCGCAGAGGATATTGGAAGTGATACCACGCTCTTACAATGGGTTGTGAATAGCTTTAATCTATTTTTTGCGTGTT
TTACGCTCATTTGGGGTGCTATAAGTGATAGATTAGGTGCAAAAACTTGTCTTATTGCTGGGGTGGCAACCTATCTTTTA
GGCTCAATACTCTCATTTCTCGCTCCTAGCCTACTTTGGCTTGATGTGGGTAGAGCCTTAGCGGGGATTGGTGGGGCAAG
TGTTTTTGCGTGTGGAAGTGCTATTTTAATCCGCACTTTTGAAGACAAGGAACGAGTGAAAGCCTTTGCATTTTTTGGCA
CAACCGCAGGGCTTGGCATTACCTTAGGACCCACATTAAGTGGATTCCTCATTGATCTTTTTGCGTGGAGGGCGATTTTT
GTCTTTCATTTTCTCACACTTGGGGTTGTTTTGCTCCTTTCACCTATGTTGCCAAAAGACCCACAAAAACAACAAAAAGC
CTTTAAGTTTGATAAAATGGGTGCACTTCTCTTTATCGCTTTTATGTCAAGCTTTATGCTTTTTATCACCAAAATCCACG
CTTTCAAAGAGCCTCAAACACTTGGAATATTAGCCTTTTGTCTCATTGTAGGGATAGTTTTTGGGGTGCATCAGAGAAGT
TTGCACTATAAAAATATTACACCAAATCCTACCCTGCACATTCCTCAACCGCTTTTAGACTTTGAAGTGCTTAAAAATGC
TTCGTTTTTTGGATTTAGCCTTGTAGCAGTGATTGCTGGATTTAGCTTTGTCGTATTACTCACTTATTTTCCTACTTTTC
TCTCTATAAACTTTGGATTCTCTGCCTCTTTTTCTGGGCTTTTTATGCTCTCCCTCACTACGCCTATGCTATTTTGTCCA
ATTCTTGCAGGAAAAATGCTAAACAAAGGGGTAGATTCTAAAGCTCTTGCCCTTGCAATGTCTTTGATGATGAGCTTAGG
AATCTTTGCACTTTTAATCATCTTGCATACTCTAAGCGGTGTTACGCTTCAGCTAATGACGCTTTTAGTGCTTTTTGTTA
TTGGCTGTGGTATGGGATTACACGCAGGGGCGATTGATGGATTGGCTCTTGGGAGTGTAGAATCTGCTAAAAGTGGCTTA
GGCGCAGGAGTGCTTAATTCCTTGCGTTTAGGCTCTGAAGCGGTGGGAGTAAGCCTCTATGGCGCACTTATGGTGGTGTT
TATTACCGCAAATCTCTCCTATCTTTTGGATAGTGAAGATTCTGTGTATCCCATTGTGGAAAGTATCGCAAGTGGAAATC
TTAGTGCGGTTGAGAATCCGCTGATTTCAGCAAATGCACCCTCTATTTATCTGCAATCTTTTTCTTACACTTTGGGAATA
TTGGGGCTTATAAGCCTTGCTTTAAGCTTAGGTGTTTGGAGATTGCTTGGGAGGGTAAAATAG

Upstream 100 bases:

>100_bases
TTGTAATACTTGACATTATAACAAAACTGCTTTATACTTCCTCTATTACTAGTTGTAATATTATTTATTACATTAAAAAG
GCTAAAATCAAGGAGACCCA

Downstream 100 bases:

>100_bases
AGTGCTTAAACTGCATTAAGCACTTTGAAAAATCTCAATTACTCTTATTATCTTAAGCAAGATTTGCTGTTTTTCTCACT
CTACATTTTACCAAATCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MNLILFTILLAVFVVPSSISGTAIALPYIAEDIGSDTTLLQWVVNSFNLFFACFTLIWGAISDRLGAKTCLIAGVATYLL
GSILSFLAPSLLWLDVGRALAGIGGASVFACGSAILIRTFEDKERVKAFAFFGTTAGLGITLGPTLSGFLIDLFAWRAIF
VFHFLTLGVVLLLSPMLPKDPQKQQKAFKFDKMGALLFIAFMSSFMLFITKIHAFKEPQTLGILAFCLIVGIVFGVHQRS
LHYKNITPNPTLHIPQPLLDFEVLKNASFFGFSLVAVIAGFSFVVLLTYFPTFLSINFGFSASFSGLFMLSLTTPMLFCP
ILAGKMLNKGVDSKALALAMSLMMSLGIFALLIILHTLSGVTLQLMTLLVLFVIGCGMGLHAGAIDGLALGSVESAKSGL
GAGVLNSLRLGSEAVGVSLYGALMVVFITANLSYLLDSEDSVYPIVESIASGNLSAVENPLISANAPSIYLQSFSYTLGI
LGLISLALSLGVWRLLGRVK

Sequences:

>Translated_500_residues
MNLILFTILLAVFVVPSSISGTAIALPYIAEDIGSDTTLLQWVVNSFNLFFACFTLIWGAISDRLGAKTCLIAGVATYLL
GSILSFLAPSLLWLDVGRALAGIGGASVFACGSAILIRTFEDKERVKAFAFFGTTAGLGITLGPTLSGFLIDLFAWRAIF
VFHFLTLGVVLLLSPMLPKDPQKQQKAFKFDKMGALLFIAFMSSFMLFITKIHAFKEPQTLGILAFCLIVGIVFGVHQRS
LHYKNITPNPTLHIPQPLLDFEVLKNASFFGFSLVAVIAGFSFVVLLTYFPTFLSINFGFSASFSGLFMLSLTTPMLFCP
ILAGKMLNKGVDSKALALAMSLMMSLGIFALLIILHTLSGVTLQLMTLLVLFVIGCGMGLHAGAIDGLALGSVESAKSGL
GAGVLNSLRLGSEAVGVSLYGALMVVFITANLSYLLDSEDSVYPIVESIASGNLSAVENPLISANAPSIYLQSFSYTLGI
LGLISLALSLGVWRLLGRVK
>Mature_500_residues
MNLILFTILLAVFVVPSSISGTAIALPYIAEDIGSDTTLLQWVVNSFNLFFACFTLIWGAISDRLGAKTCLIAGVATYLL
GSILSFLAPSLLWLDVGRALAGIGGASVFACGSAILIRTFEDKERVKAFAFFGTTAGLGITLGPTLSGFLIDLFAWRAIF
VFHFLTLGVVLLLSPMLPKDPQKQQKAFKFDKMGALLFIAFMSSFMLFITKIHAFKEPQTLGILAFCLIVGIVFGVHQRS
LHYKNITPNPTLHIPQPLLDFEVLKNASFFGFSLVAVIAGFSFVVLLTYFPTFLSINFGFSASFSGLFMLSLTTPMLFCP
ILAGKMLNKGVDSKALALAMSLMMSLGIFALLIILHTLSGVTLQLMTLLVLFVIGCGMGLHAGAIDGLALGSVESAKSGL
GAGVLNSLRLGSEAVGVSLYGALMVVFITANLSYLLDSEDSVYPIVESIASGNLSAVENPLISANAPSIYLQSFSYTLGI
LGLISLALSLGVWRLLGRVK

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=409, Percent_Identity=23.2273838630807, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790195, Length=407, Percent_Identity=26.5356265356265, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790146, Length=177, Percent_Identity=26.5536723163842, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323735, Length=324, Percent_Identity=26.8518518518519, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53359; Mature: 53359

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLILFTILLAVFVVPSSISGTAIALPYIAEDIGSDTTLLQWVVNSFNLFFACFTLIWGA
CHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISDRLGAKTCLIAGVATYLLGSILSFLAPSLLWLDVGRALAGIGGASVFACGSAILIRTF
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEC
EDKERVKAFAFFGTTAGLGITLGPTLSGFLIDLFAWRAIFVFHFLTLGVVLLLSPMLPKD
CHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PQKQQKAFKFDKMGALLFIAFMSSFMLFITKIHAFKEPQTLGILAFCLIVGIVFGVHQRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
LHYKNITPNPTLHIPQPLLDFEVLKNASFFGFSLVAVIAGFSFVVLLTYFPTFLSINFGF
CEECCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
SASFSGLFMLSLTTPMLFCPILAGKMLNKGVDSKALALAMSLMMSLGIFALLIILHTLSG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTLQLMTLLVLFVIGCGMGLHAGAIDGLALGSVESAKSGLGAGVLNSLRLGSEAVGVSLY
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHH
GALMVVFITANLSYLLDSEDSVYPIVESIASGNLSAVENPLISANAPSIYLQSFSYTLGI
HHHHHHHHHHCHHHEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHH
LGLISLALSLGVWRLLGRVK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLILFTILLAVFVVPSSISGTAIALPYIAEDIGSDTTLLQWVVNSFNLFFACFTLIWGA
CHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISDRLGAKTCLIAGVATYLLGSILSFLAPSLLWLDVGRALAGIGGASVFACGSAILIRTF
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEC
EDKERVKAFAFFGTTAGLGITLGPTLSGFLIDLFAWRAIFVFHFLTLGVVLLLSPMLPKD
CHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PQKQQKAFKFDKMGALLFIAFMSSFMLFITKIHAFKEPQTLGILAFCLIVGIVFGVHQRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
LHYKNITPNPTLHIPQPLLDFEVLKNASFFGFSLVAVIAGFSFVVLLTYFPTFLSINFGF
CEECCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
SASFSGLFMLSLTTPMLFCPILAGKMLNKGVDSKALALAMSLMMSLGIFALLIILHTLSG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTLQLMTLLVLFVIGCGMGLHAGAIDGLALGSVESAKSGLGAGVLNSLRLGSEAVGVSLY
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHH
GALMVVFITANLSYLLDSEDSVYPIVESIASGNLSAVENPLISANAPSIYLQSFSYTLGI
HHHHHHHHHHCHHHEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHH
LGLISLALSLGVWRLLGRVK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]