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The map label for this gene is ykkC [H]

Identifier: 32266950

GI number: 32266950

Start: 1398440

End: 1398871

Strand: Direct

Name: ykkC [H]

Synonym: HH1451

Alternate gene names: 32266950

Gene position: 1398440-1398871 (Clockwise)

Preceding gene: 32266949

Following gene: 32266951

Centisome position: 77.73

GC content: 41.2

Gene sequence:

>432_bases
ATGAAAAATATCAAACTTACCCACAATCTCGCGTGGGGATTGGTGCTTTTTGGTGGCATTGTAGAATGCTTTTGGGCGAG
TGGGTTAAAATATTCCGATAATCTCTTTTTTTACACACTCACAGGAATTGGGATTCTCATATCCTTTGTAAGTATGATTC
TAGCGATAAAAGTCTTAGAGATTGGTATTGCTTATAGCGTGTTTGTGGGGATTGGCACAGCGGGCATTACACTTGCTGAA
ATCCTTATCTTTGGTGAGCCTTTCTCACCTCTTAAAATCCTCTTTATCGCGACCTTACTTCTTGGCGTGGTGGGGCTAAA
GCTTTCAGCAGATAAGACAGAGGAATCTCAAGGAGAAAAACTTGCAGAAACGCTCTCACACGATTTGGGAATTGATGAAA
TCGTGCAAGATTCTATCAAGGAGGCAAAATGA

Upstream 100 bases:

>100_bases
TAATCATTTCACATAAATTCTAATCACATTTATGGGCTTTGGCTTTTTAAACCCATAAAATGTATAAAATAAAACATATA
AAATAAAACAAAGGAAACAA

Downstream 100 bases:

>100_bases
GTTGGGTGTATCTCATAATGGCTGGTTGTATGGAAATCATAGGCGTAATTACGATGAAAAAATACTCCCTAAGTGGGCGA
AAAATCTTTTTGCTTGGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKNIKLTHNLAWGLVLFGGIVECFWASGLKYSDNLFFYTLTGIGILISFVSMILAIKVLEIGIAYSVFVGIGTAGITLAE
ILIFGEPFSPLKILFIATLLLGVVGLKLSADKTEESQGEKLAETLSHDLGIDEIVQDSIKEAK

Sequences:

>Translated_143_residues
MKNIKLTHNLAWGLVLFGGIVECFWASGLKYSDNLFFYTLTGIGILISFVSMILAIKVLEIGIAYSVFVGIGTAGITLAE
ILIFGEPFSPLKILFIATLLLGVVGLKLSADKTEESQGEKLAETLSHDLGIDEIVQDSIKEAK
>Mature_143_residues
MKNIKLTHNLAWGLVLFGGIVECFWASGLKYSDNLFFYTLTGIGILISFVSMILAIKVLEIGIAYSVFVGIGTAGITLAE
ILIFGEPFSPLKILFIATLLLGVVGLKLSADKTEESQGEKLAETLSHDLGIDEIVQDSIKEAK

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=36.1904761904762, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 15450; Mature: 15450

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIKLTHNLAWGLVLFGGIVECFWASGLKYSDNLFFYTLTGIGILISFVSMILAIKVLE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
IGIAYSVFVGIGTAGITLAEILIFGEPFSPLKILFIATLLLGVVGLKLSADKTEESQGEK
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LAETLSHDLGIDEIVQDSIKEAK
HHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKNIKLTHNLAWGLVLFGGIVECFWASGLKYSDNLFFYTLTGIGILISFVSMILAIKVLE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
IGIAYSVFVGIGTAGITLAEILIFGEPFSPLKILFIATLLLGVVGLKLSADKTEESQGEK
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LAETLSHDLGIDEIVQDSIKEAK
HHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA