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The map label for this gene is engD [H]

Identifier: 32266872

GI number: 32266872

Start: 1326545

End: 1327645

Strand: Direct

Name: engD [H]

Synonym: HH1373

Alternate gene names: 32266872

Gene position: 1326545-1327645 (Clockwise)

Preceding gene: 32266871

Following gene: 32266876

Centisome position: 73.73

GC content: 38.87

Gene sequence:

>1101_bases
ATGGGATTATCAATCGGTATTGTAGGGTTGCCAAATGTTGGTAAATCTACGACTTTTAATGCTCTCACAAAAGCACAAAA
TGCGGAGGCAGCAAATTATCCTTTTTGCACGATTGAGCCAAATAAGGCAGTTGTGAGTGTGCCTGATGTAAGGTTGCAAG
AGTTGGCTAAAATTGTCAATCCTCAAAAGATTCAGCACTCTGTCGTGGAGTTTGTGGATATTGCCGGACTTGTGCGAGGT
GCGAGTAAAGGTGAGGGATTAGGCAATCAATTTTTAGCAAATATTAAAGAATGTAATATGATTTTGCATATCGTGCGGTG
TTTTGAGGATTCTAATATCACGCATATTGAGGGGCGCATTGACCCGATTGATGATATTGAAATTATTGAGTTAGAACTGC
TTTTTGCCGATATGGCAAGTTTAAATAAACGCATTGAGAAACTCCAAAGAGAGAGCAAATCTCAAAAAGGCGTAAATACT
CAACTTACTCTCTGCCAAGAGCTTTTAGCGCATTTAGAATCTAATAAGCCCGTGCGAAGCTTTGCTAAACGTGAAAGTGA
GGAATTTATCGCACTCAATAAGGATTTAAGATTTTTAACCAATAAAGAAGTGATTTATGGGGCAAATGTCAATGAAGAGG
GCTTAGAATCTGATAATGAGTTTGTGCAAAAAGTGCGTGAATATGCAGCGCAAAATGATGGTATAGCAATTAAGCTGTGT
GCAAAGATTGAAGAGGAAATGGTAGATATGAGTGATGATGAGCGCACAGAGTTTTTAGTAAGTCTTGGAGCAAAGCAGAG
TGGATTAACGCAGATTATTAGAGAGGGATTTGCACGACTTGGGCTTATAAGTTATTTTACTGCAGGTGTCAAAGAAGTGC
GAGCTTGGAGCATTAGAAAAGGAGATAGTGCGCCAAAAGCTGCAAGTGTGATACATAAAGACTTTGAAAAAGGTTTTATT
CGTGCGGAGTGTATCAGTTATGCAGATTTTATTAAATATGGTGGCGAGGCAAAAGCAAAAGAAGCTGGGGCTATGCGTAT
TGAAGGTAAAGAATATATCGTGCAAGATGGTGATGTAATGCACTTTAGATTCAATGTCTAA

Upstream 100 bases:

>100_bases
CGCGTATGTGGAAAAAGAGTGGGATATTAACCCAAGTGGAGCGAGTGGTGCAGGCGTGAGGGCAGGAATAGAATTTATTT
TAGCACAAGGAAAAGCATAA

Downstream 100 bases:

>100_bases
CCTTGCATTTACAAAAAAAAAAAAAAAACGATACAATACGCAGATGAAAGATGCTTCATACAGAGAGGGGTATAATGCAA
AACACACAAGAAAAGATAGT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGLSIGIVGLPNVGKSTTFNALTKAQNAEAANYPFCTIEPNKAVVSVPDVRLQELAKIVNPQKIQHSVVEFVDIAGLVRG
ASKGEGLGNQFLANIKECNMILHIVRCFEDSNITHIEGRIDPIDDIEIIELELLFADMASLNKRIEKLQRESKSQKGVNT
QLTLCQELLAHLESNKPVRSFAKRESEEFIALNKDLRFLTNKEVIYGANVNEEGLESDNEFVQKVREYAAQNDGIAIKLC
AKIEEEMVDMSDDERTEFLVSLGAKQSGLTQIIREGFARLGLISYFTAGVKEVRAWSIRKGDSAPKAASVIHKDFEKGFI
RAECISYADFIKYGGEAKAKEAGAMRIEGKEYIVQDGDVMHFRFNV

Sequences:

>Translated_366_residues
MGLSIGIVGLPNVGKSTTFNALTKAQNAEAANYPFCTIEPNKAVVSVPDVRLQELAKIVNPQKIQHSVVEFVDIAGLVRG
ASKGEGLGNQFLANIKECNMILHIVRCFEDSNITHIEGRIDPIDDIEIIELELLFADMASLNKRIEKLQRESKSQKGVNT
QLTLCQELLAHLESNKPVRSFAKRESEEFIALNKDLRFLTNKEVIYGANVNEEGLESDNEFVQKVREYAAQNDGIAIKLC
AKIEEEMVDMSDDERTEFLVSLGAKQSGLTQIIREGFARLGLISYFTAGVKEVRAWSIRKGDSAPKAASVIHKDFEKGFI
RAECISYADFIKYGGEAKAKEAGAMRIEGKEYIVQDGDVMHFRFNV
>Mature_365_residues
GLSIGIVGLPNVGKSTTFNALTKAQNAEAANYPFCTIEPNKAVVSVPDVRLQELAKIVNPQKIQHSVVEFVDIAGLVRGA
SKGEGLGNQFLANIKECNMILHIVRCFEDSNITHIEGRIDPIDDIEIIELELLFADMASLNKRIEKLQRESKSQKGVNTQ
LTLCQELLAHLESNKPVRSFAKRESEEFIALNKDLRFLTNKEVIYGANVNEEGLESDNEFVQKVREYAAQNDGIAIKLCA
KIEEEMVDMSDDERTEFLVSLGAKQSGLTQIIREGFARLGLISYFTAGVKEVRAWSIRKGDSAPKAASVIHKDFEKGFIR
AECISYADFIKYGGEAKAKEAGAMRIEGKEYIVQDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=372, Percent_Identity=44.6236559139785, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI58761502, Length=206, Percent_Identity=40.7766990291262, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=53.9509536784741, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1789574, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=42.3913043478261, Blast_Score=287, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=36.9973190348526, Blast_Score=228, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=35.7894736842105, Blast_Score=212, Evalue=9e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=426, Percent_Identity=26.2910798122066, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=41.3978494623656, Blast_Score=278, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=41.3978494623656, Blast_Score=278, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=41.3978494623656, Blast_Score=278, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24640879, Length=330, Percent_Identity=38.4848484848485, Blast_Score=224, Evalue=6e-59,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40708; Mature: 40577

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSIGIVGLPNVGKSTTFNALTKAQNAEAANYPFCTIEPNKAVVSVPDVRLQELAKIVN
CCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHC
PQKIQHSVVEFVDIAGLVRGASKGEGLGNQFLANIKECNMILHIVRCFEDSNITHIEGRI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
DPIDDIEIIELELLFADMASLNKRIEKLQRESKSQKGVNTQLTLCQELLAHLESNKPVRS
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
FAKRESEEFIALNKDLRFLTNKEVIYGANVNEEGLESDNEFVQKVREYAAQNDGIAIKLC
HHHCCCHHEEEECCCHHHCCCCCEEEECCCCHHCCCCHHHHHHHHHHHHCCCCCEEEEEH
AKIEEEMVDMSDDERTEFLVSLGAKQSGLTQIIREGFARLGLISYFTAGVKEVRAWSIRK
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDSAPKAASVIHKDFEKGFIRAECISYADFIKYGGEAKAKEAGAMRIEGKEYIVQDGDVM
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC
>Mature Secondary Structure 
GLSIGIVGLPNVGKSTTFNALTKAQNAEAANYPFCTIEPNKAVVSVPDVRLQELAKIVN
CCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHC
PQKIQHSVVEFVDIAGLVRGASKGEGLGNQFLANIKECNMILHIVRCFEDSNITHIEGRI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
DPIDDIEIIELELLFADMASLNKRIEKLQRESKSQKGVNTQLTLCQELLAHLESNKPVRS
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
FAKRESEEFIALNKDLRFLTNKEVIYGANVNEEGLESDNEFVQKVREYAAQNDGIAIKLC
HHHCCCHHEEEECCCHHHCCCCCEEEECCCCHHCCCCHHHHHHHHHHHHCCCCCEEEEEH
AKIEEEMVDMSDDERTEFLVSLGAKQSGLTQIIREGFARLGLISYFTAGVKEVRAWSIRK
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDSAPKAASVIHKDFEKGFIRAECISYADFIKYGGEAKAKEAGAMRIEGKEYIVQDGDVM
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA