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The map label for this gene is groES

Identifier: 32266699

GI number: 32266699

Start: 1168356

End: 1168628

Strand: Direct

Name: groES

Synonym: HH1200

Alternate gene names: 32266699

Gene position: 1168356-1168628 (Clockwise)

Preceding gene: 32266694

Following gene: 32266700

Centisome position: 64.94

GC content: 34.07

Gene sequence:

>273_bases
ATGAAGTTTAGACCTTTGGGAGAGAGAGTTCTCGTAGAACGCGTGGAAGAAGATACTAAAACAAGTTCGGGTATTATTAT
TCCTGATAATGCTAAAGAAAAACCTCTTATGGGTATAGTAAAGGCAGTAAGTGCTAAAATCAAAGACGACAAAATATTGA
AAGAAAATGATAAAGTCGTATTTGGTAAATATAAGGGCGCAGAAATCAAGCTAGATTCAAAGGAGTTTATTGTCCTAGAG
CTAGATGATATTTTGGGCGTTATTGAAAAATAA

Upstream 100 bases:

>100_bases
AATATAAAGTATTGACTTGTTTAACAAAAAAATATAAAATTTCGCACTTCAAAAATTAAGTGCTAAAATTTTTGATTAAT
TATTTATAAAGGAGTTGATT

Downstream 100 bases:

>100_bases
ATTTTAGAATCTTAAACATTAAAGGAGTAAAAAATGGCAAGCAAAGAAATTAACTTTTCAGATTCGGCAAGGAATAAGCT
CTATGAGGGCATTAAGCAAT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MKFRPLGERVLVERVEEDTKTSSGIIIPDNAKEKPLMGIVKAVSAKIKDDKILKENDKVVFGKYKGAEIKLDSKEFIVLE
LDDILGVIEK

Sequences:

>Translated_90_residues
MKFRPLGERVLVERVEEDTKTSSGIIIPDNAKEKPLMGIVKAVSAKIKDDKILKENDKVVFGKYKGAEIKLDSKEFIVLE
LDDILGVIEK
>Mature_90_residues
MKFRPLGERVLVERVEEDTKTSSGIIIPDNAKEKPLMGIVKAVSAKIKDDKILKENDKVVFGKYKGAEIKLDSKEFIVLE
LDDILGVIEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=34.4086021505376, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_HELHP (Q7U318)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860731.1
- ProteinModelPortal:   Q7U318
- SMR:   Q7U318
- GeneID:   1492888
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1200
- NMPDR:   fig|235279.1.peg.1200
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- ProtClustDB:   PRK00364
- BioCyc:   HHEP235279:HH_1200-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10114; Mature: 10114

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRPLGERVLVERVEEDTKTSSGIIIPDNAKEKPLMGIVKAVSAKIKDDKILKENDKVV
CCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCEE
FGKYKGAEIKLDSKEFIVLELDDILGVIEK
EEECCCCEEEECCCCEEEEEECHHHHHCCC
>Mature Secondary Structure
MKFRPLGERVLVERVEEDTKTSSGIIIPDNAKEKPLMGIVKAVSAKIKDDKILKENDKVV
CCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCEE
FGKYKGAEIKLDSKEFIVLELDDILGVIEK
EEECCCCEEEECCCCEEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954