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The map label for this gene is neuA

Identifier: 32266399

GI number: 32266399

Start: 876702

End: 877409

Strand: Direct

Name: neuA

Synonym: HH0900

Alternate gene names: 32266399

Gene position: 876702-877409 (Clockwise)

Preceding gene: 32266398

Following gene: 32266405

Centisome position: 48.73

GC content: 39.55

Gene sequence:

>708_bases
GTGAGAAAAGTCGCTCTTATCCCTGCTCGTGGTGGAAGTAAAAGGATACCTGATAAAAATATCAAGCCCTTTTGTGGCAA
ACCTATCATTGCTTATCCTATTATTACAGCATTAGAATCTGCACTTTTTGATGAAGTCATAGTCAGCACAGATTCTACAC
AAATCGCACAAGTTGCGTGTGAATATGGAGCAAAAGTGCCCTTTATGCGCCCAAAAGAGCTAAGTGATGACTTTACCCCC
ACTGCACCTGTGGCAAAACACGCCGTAGAATCACTAAAATTACACAAAGAGGATTTGCTCTGCGTGATTTATCCCACTGC
ACCTTTGCTTACTCAAAAAACACTCTCTCTTGGACTAAAGGCTCTTTTAGAAAATCCGCACAAACTCTTTGCTTTTTGTG
CTGTAAGCTATTATTATAATCCTTATCGGAGTTTTTGCATCAAAAATGATGAGATAGAAATGCTTTTTCCAAAGCATTAT
CTCACGCGCTCACAAGATTTAGAGCAAGTCTATCACGATGCGGGGCAGTGCTATTGGGGATATGTGAATGCGTGGAGAGA
ATCTCTGCCTATTTTTGCACCTCATTCAAGTGCAATAATTGTGCCAAGTAAAGAAGTCCAAGACATTGATACACTTGAGG
ATTGGGCAATGGCAGAGATGAAGTATAGACTTTTAGAAGATTCTATAAACAAGAATATAGAATCTTAA

Upstream 100 bases:

>100_bases
AAATTGCCTACACTTCGCTAGGACCAATCAGTGATACAAATCATAAAAAACCTGTAAGCGATGGCATAGAATCTCTGTAT
CCCTTTTAGTCGGTAAGTGT

Downstream 100 bases:

>100_bases
AGCTATACCAATGAACAAATATACTCAAATTGCTCTTTTGTCGTAGCAAAATATGTCCCAAAGAGTAAATTATTTTGGCT
TTCATTAAATGGAGCATATT

Product: acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRKVALIPARGGSKRIPDKNIKPFCGKPIIAYPIITALESALFDEVIVSTDSTQIAQVACEYGAKVPFMRPKELSDDFTP
TAPVAKHAVESLKLHKEDLLCVIYPTAPLLTQKTLSLGLKALLENPHKLFAFCAVSYYYNPYRSFCIKNDEIEMLFPKHY
LTRSQDLEQVYHDAGQCYWGYVNAWRESLPIFAPHSSAIIVPSKEVQDIDTLEDWAMAEMKYRLLEDSINKNIES

Sequences:

>Translated_235_residues
MRKVALIPARGGSKRIPDKNIKPFCGKPIIAYPIITALESALFDEVIVSTDSTQIAQVACEYGAKVPFMRPKELSDDFTP
TAPVAKHAVESLKLHKEDLLCVIYPTAPLLTQKTLSLGLKALLENPHKLFAFCAVSYYYNPYRSFCIKNDEIEMLFPKHY
LTRSQDLEQVYHDAGQCYWGYVNAWRESLPIFAPHSSAIIVPSKEVQDIDTLEDWAMAEMKYRLLEDSINKNIES
>Mature_235_residues
MRKVALIPARGGSKRIPDKNIKPFCGKPIIAYPIITALESALFDEVIVSTDSTQIAQVACEYGAKVPFMRPKELSDDFTP
TAPVAKHAVESLKLHKEDLLCVIYPTAPLLTQKTLSLGLKALLENPHKLFAFCAVSYYYNPYRSFCIKNDEIEMLFPKHY
LTRSQDLEQVYHDAGQCYWGYVNAWRESLPIFAPHSSAIIVPSKEVQDIDTLEDWAMAEMKYRLLEDSINKNIES

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=107, Percent_Identity=42.9906542056075, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 26647; Mature: 26647

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVALIPARGGSKRIPDKNIKPFCGKPIIAYPIITALESALFDEVIVSTDSTQIAQVAC
CCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EYGAKVPFMRPKELSDDFTPTAPVAKHAVESLKLHKEDLLCVIYPTAPLLTQKTLSLGLK
HHCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHH
ALLENPHKLFAFCAVSYYYNPYRSFCIKNDEIEMLFPKHYLTRSQDLEQVYHDAGQCYWG
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHHHHHHHCCCEEHH
YVNAWRESLPIFAPHSSAIIVPSKEVQDIDTLEDWAMAEMKYRLLEDSINKNIES
HHHHHHHCCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKVALIPARGGSKRIPDKNIKPFCGKPIIAYPIITALESALFDEVIVSTDSTQIAQVAC
CCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EYGAKVPFMRPKELSDDFTPTAPVAKHAVESLKLHKEDLLCVIYPTAPLLTQKTLSLGLK
HHCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHH
ALLENPHKLFAFCAVSYYYNPYRSFCIKNDEIEMLFPKHYLTRSQDLEQVYHDAGQCYWG
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHHHHHHHCCCEEHH
YVNAWRESLPIFAPHSSAIIVPSKEVQDIDTLEDWAMAEMKYRLLEDSINKNIES
HHHHHHHCCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]