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The map label for this gene is fur

Identifier: 32266392

GI number: 32266392

Start: 870931

End: 871392

Strand: Direct

Name: fur

Synonym: HH0893

Alternate gene names: 32266392

Gene position: 870931-871392 (Clockwise)

Preceding gene: 32266386

Following gene: 32266398

Centisome position: 48.41

GC content: 34.85

Gene sequence:

>462_bases
ATGAATATGAATGCAAATCATCGCGTGGAAACACTAGATTCTATACTTGAAAGGTTAAGAAGCTCAATTAAAAAAAATGG
GCTTAAAAATTCTAAACAACGCGAAGAAATCATTGCTGTGCTATATAAAAGTGGTACACATCTTAGCCCTGAAGAGATTA
CTAATATTATCAAAACAACTGATAAAAATGCAAGTATCTCCTCTGTATATAGAATCCTAAGCTTCCTTGAAAAAGAGGGA
TTTATTACTGCTCTTGAGGCTGATAAAAGTGGAAGACGCTATGAAATTGCTGCCAAAGAACATCACGACCATATTATTTG
TTTAGCTTGTGGCGACATTATAGAGTTTGTAGATGCAGATATTGAACGTTTGCAACTTGATATTGCACAACAATTTGGCG
CAAAACTCATCAGCCACGATATGAGATTATTTGTCAAATGCTCGAAATGTCAAGGACTCTAA

Upstream 100 bases:

>100_bases
TATTTAATGATAAGCTTTCTTATTTGCATTTTTGTATTTTGTTGCTATAATCCTGCATAAAATAAGAATCGCAATCCTAA
AAGCGCAACAAGGAGCGTAT

Downstream 100 bases:

>100_bases
AGGTTTAATTAAAAACTAAAATTCATTTGTGTATAATCACGCTTTGCTAAAACTTAAGCAATAAAGGACGTGTAGCTCAG
CTGGTAGAGCAACTGACTCT

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MNMNANHRVETLDSILERLRSSIKKNGLKNSKQREEIIAVLYKSGTHLSPEEITNIIKTTDKNASISSVYRILSFLEKEG
FITALEADKSGRRYEIAAKEHHDHIICLACGDIIEFVDADIERLQLDIAQQFGAKLISHDMRLFVKCSKCQGL

Sequences:

>Translated_153_residues
MNMNANHRVETLDSILERLRSSIKKNGLKNSKQREEIIAVLYKSGTHLSPEEITNIIKTTDKNASISSVYRILSFLEKEG
FITALEADKSGRRYEIAAKEHHDHIICLACGDIIEFVDADIERLQLDIAQQFGAKLISHDMRLFVKCSKCQGL
>Mature_153_residues
MNMNANHRVETLDSILERLRSSIKKNGLKNSKQREEIIAVLYKSGTHLSPEEITNIIKTTDKNASISSVYRILSFLEKEG
FITALEADKSGRRYEIAAKEHHDHIICLACGDIIEFVDADIERLQLDIAQQFGAKLISHDMRLFVKCSKCQGL

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=130, Percent_Identity=32.3076923076923, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17345; Mature: 17345

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMNANHRVETLDSILERLRSSIKKNGLKNSKQREEIIAVLYKSGTHLSPEEITNIIKTT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
DKNASISSVYRILSFLEKEGFITALEADKSGRRYEIAAKEHHDHIICLACGDIIEFVDAD
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHH
IERLQLDIAQQFGAKLISHDMRLFVKCSKCQGL
HHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCC
>Mature Secondary Structure
MNMNANHRVETLDSILERLRSSIKKNGLKNSKQREEIIAVLYKSGTHLSPEEITNIIKTT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
DKNASISSVYRILSFLEKEGFITALEADKSGRRYEIAAKEHHDHIICLACGDIIEFVDAD
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHH
IERLQLDIAQQFGAKLISHDMRLFVKCSKCQGL
HHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]